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Brief Title: QUILT-2.015: A Study of AMG 479 With Exemestane or Fulvestrant in Postmenopausal Women With Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer
Official Title: An International, Randomized, Double-blind, Placebo-controlled, Phase 2 Study of AMG 479 With Exemestane or Fulvestrant in Postmenopausal Women With Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer
Study ID: NCT00626106
Brief Summary: This is a randomized, double-blind, placebo-controlled, phase 2 study. Subjects will include postmenopausal women with confirmed HR-positive, locally advanced or metastatic breast cancer, who have disease progression during or within 12 months after completing prior adjuvant endocrine therapy or during the first prior endocrine therapy for metastatic disease.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Research Site, Chandler, Arizona, United States
Research Site, Anaheim, California, United States
Research Site, Beverly Hills, California, United States
Research Site, Concord, California, United States
Research Site, Duarte, California, United States
Research Site, Montebello, California, United States
Research Site, San Francisco, California, United States
Research Site, Sylmar, California, United States
Research Site, Stamford, Connecticut, United States
Research Site, Boca Raton, Florida, United States
Research Site, Boynton Beach, Florida, United States
Research Site, Coral Springs, Florida, United States
Research Site, Gainesville, Florida, United States
Research Site, Lake Worth, Florida, United States
Research Site, Atlanta, Georgia, United States
Research Site, Marietta, Georgia, United States
Research Site, Chicago, Illinois, United States
Research Site, Lebanon, New Hampshire, United States
Research Site, Denville, New Jersey, United States
Research Site, High Point, North Carolina, United States
Research Site, Hershey, Pennsylvania, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, Memphis, Tennessee, United States
Research Site, American Fork, Utah, United States
Research Site, Tacoma, Washington, United States
Research Site, Waratah, New South Wales, Australia
Research Site, Woodville South, South Australia, Australia
Research Site, Footscray, Victoria, Australia
Research Site, Geelong, Victoria, Australia
Research Site, Malvern, Victoria, Australia
Research Site, Vancouver, British Columbia, Canada
Research Site, Ottawa, Ontario, Canada
Research Site, Sault Ste. Marie, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Dijon, , France
Research Site, Le Mans, , France
Research Site, Lyon, , France
Research Site, Montpellier Cedex 5, , France
Research Site, Nice Cedex 2, , France
Research Site, Paris Cedex 5, , France
Research Site, Reims Cedex, , France
Research Site, Saint Herblain, , France
Research Site, Frankfurt, , Germany
Research Site, Frankfurt, , Germany
Research Site, Hannover, , Germany
Research Site, München, , Germany
Research Site, Dublin, , Ireland
Research Site, Dublin, , Ireland
Research Site, Barcelona, Cataluña, Spain
Research Site, L'Hospitalet de Llobregat, Cataluña, Spain
Research Site, Sabadell, Cataluña, Spain
Research Site, Madrid, , Spain
Research Site, Chur, , Switzerland
Research Site, Luzern 16, , Switzerland
Research Site, Zurich, , Switzerland
Research Site, Derby, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Peterborough, , United Kingdom
Name: MD
Affiliation: Amgen
Role: STUDY_DIRECTOR