Spots Global Cancer Trial Database for Body Composition and White Adipose Tissue Inflammation
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Trial Identification
Brief Title: Body Composition and White Adipose Tissue Inflammation
Official Title: Body Composition and White Adipose Tissue Inflammation
Study ID: NCT02713022
Study Description
Brief Summary: The investigators want to find a better way to predict the risk of having fatty tissue inflammation by using a different approach to finding out body fat composition. In this study, the investigators want to estimate the body fat composition using a DEXA scan. DEXA stands for dual energy X-ray absorptiometry. It is the standard and established test to determine bone mineral density (how strong the bones are) to diagnose osteoporosis. This test can also be used to determine the body composition including percent body fat and lean mass. The investigators will compare the participants DEXA scan results for body fat composition to the inflammation found in the breast tissue from the mastectomy to see if there is a relationship. If successful, this may help us predict which patients may be at risk for breast cancer in the future. In addition, the investigators will compare the participants DEXA scan results for body fat composition and inflammation found in the fat tissue from the mastectomy or prostatectomy to the level of exercise activity as measured by a short questionnaire to see if there is a relationship. The investigators will also measure the participants waist to hip ratio. Finally, at the time the participant has blood drawn for their standard presurgical testing, the investigators will also test the blood for prediabetes using a blood test called hemoglocin A1c. The investigators will also measure for the participants waist to hip ratio, and a Hgb A1c blood drawn will be take at the time of presurgical testing. If not feasible, Hgb A1c can be drawn at a separate visit prior to the DEXA scan. If successful, this may help us predict which patients may be at risk for breast cancer in the future.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Waters Corporation (Data Analysis Only), Milford, Massachusetts, United States
Memorial Sloan Kettering Cancer Center (Consent Only), Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth (Consent Only), Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen (Consent only), Montvale, New Jersey, United States
Memorial Sloan Kettering Cancer Center @ Commack (Consent Only), Commack, New York, United States
Memorial Sloan Kettering Westchester (Consent Only), Harrison, New York, United States
Weill Medical College of Cornell University (Data and Specimen Analysis Only), New York, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Memorial Sloan Kettering Nassau (Consent only), Uniondale, New York, United States
Contact Details
Name: Neil Iyengar, MD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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