Spots Global Cancer Trial Database for DCE-MRI and DWI for Detection and Diagnosis of Breast Cancer
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Trial Identification
Brief Title: DCE-MRI and DWI for Detection and Diagnosis of Breast Cancer
Official Title: A Multi-Center Study Evaluating the Utility of Diffusion Weighted Imaging for Detection and Diagnosis of Breast Cancer
Study ID: NCT02022579
Interventions
Study Description
Brief Summary: A type of magnetic resonance imaging called diffusion weighted imaging (DWI) will be tested to define cancerous from non-cancerous lesions in the breast.
Detailed Description: For this study, the investigators plan to evaluate DWI scans performed in women with breast lesions identified by conventional breast MRI. The investigators will determine whether an ADC threshold can be defined for distinguishing benign and malignant lesions on DWI, assess the difference in ADC cutoffs for mass and non-mass lesions, and investigate the potential improvement in accuracy using techniques such as nonzero minimum b-value (to remove perfusion effects in the ADC measures) and normalized ADC measures (to account for variations in water content and other factors).
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
University of Washington, Seattle, Washington, United States
Contact Details
Name: Savannah Partridge, PhD
Affiliation: University of Washington
Role: PRINCIPAL_INVESTIGATOR
Name: Habib Rahbar, MD
Affiliation: University of Washington
Role: STUDY_CHAIR
Name: Thomas Chenevert, PhD
Affiliation: University of Michigan
Role: STUDY_CHAIR
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