Spots Global Cancer Trial Database for malignant
Every month we try and update this database with for malignant cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Phase II Trial for Large ER-Negative Breast Cancers | NCT01869192 | Malignant Neopl... | Epirubicin Cyclophosphamid... Docetaxel Capecitabine Radiation Thera... | 18 Years - | University of Colorado, Denver | |
| Phase Ib/II Study of MCS110 in Combination With PDR001 in Patients With Advanced Malignancies | NCT02807844 | Triple Negative... Pancreatic Carc... Melanoma Endometrial Car... | MCS110 PDR001 | 18 Years - | Novartis | |
| Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA | NCT01269853 | Glioblastoma Mu... Anaplastic Astr... | Bevacizumab Bevacizumab | 18 Years - | Northwell Health | |
| Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma | NCT03860883 | Cutaneous Melan... | Wide Local Exci... Wide Local Exci... | 18 Years - | Melanoma and Skin Cancer Trials Limited | |
| Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation | NCT05737706 | Solid Tumor Advanced Solid ... Non-small Cell ... Colo-rectal Can... Pancreatic Aden... | MRTX1133 | 18 Years - | Mirati Therapeutics Inc. | |
| Phase 1/2 Study of MRTX1719 in Solid Tumors With MTAP Deletion | NCT05245500 | Mesothelioma Non Small Cell ... Malignant Perip... Solid Tumor Pancreatic Aden... Advanced Solid ... | MRTX1719 | 18 Years - | Mirati Therapeutics Inc. | |
| The 'SILVERMAN1' Trial Single Incision Laparoscopic Versus Existing Resection (Minimal Access) for Neoplasia | NCT01319890 | Right Colon Tum... | Patients will b... | 18 Years - 85 Years | Irish Clinical Outcomes in Research and Education | |
| LAM561 With RT and TMZ for Adults With Glioblastoma | NCT04250922 | Primary Gliobla... Glioblastoma Mu... | LAM561 TMZ RT | 18 Years - 75 Years | Laminar Pharmaceuticals | |
| A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions | NCT00758316 | Malignant Pleur... | Thoracoscopy an... Thoracoscopy | 18 Years - | Singapore General Hospital | |
| Clinical Evaluation of a New Form of Cancer Therapy (Atavistic Chemotherapy) Based on the Principles of Atavistic Metamorphosis (2011) | NCT02366884 | Neoplasms | Anti-Bacterial ... Anti-Fungal Age... Anti-Protozoal ... | 1 Year - 75 Years | Dr. Frank Arguello Cancer Clinic | |
| Impact of Dietary Intervention on Tumor Immunity: the DigesT Trial | NCT03454282 | Breast Cancer Melanoma, Malig... | FMD | 18 Years - 75 Years | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | |
| A Phase II Study of Gliadel, Concomitant Temozolomide and Radiation, Followed By Dose Dense Therapy With Temozolomide For Newly Diagnosed Malignant High Grade Glioma | NCT00660283 | Glioma | Temozolomide | 18 Years - 75 Years | Kentuckiana Cancer Institute | |
| A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer | NCT00060944 | Liposarcoma Leiomyosarcoma | Yondelis Yondelis Dexamethasone Dexamethasone | 18 Years - | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | |
| A Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant Melanoma | NCT00864253 | Malignant Melan... | ABI-007 Dacarbazine | 18 Years - | Celgene | |
| Prospective Evaluation of Lymphoedema Among Patients With Gynaecological Cancer | NCT00604994 | Female Genital ... Ovarian Cancer Cervical Cancer Endometrial Can... Vulval Cancer | 18 Years - | Queensland Centre for Gynaecological Cancer | ||
| Study of Platelet Derived Growth Factor Receptor (PDGFR) in Recurrent Malignant Gliomas | NCT01140568 | Glioma | nilotinib | 18 Years - | University of California, San Diego | |
| Symptomatic Ascites Drainage With a Patient-controlled Vascular Catheter. | NCT02724683 | Malignant Ascit... | Ascites drainag... Interview. Quality of life... Quality of proc... Nutritional sta... | 18 Years - | Gdynia Oncology Center | |
| EPO906 Therapy in Patients With Advanced Melanoma | NCT00035165 | Melanoma | epothilone b | 18 Years - 85 Years | Novartis | |
| Phase Ib/II Study of MCS110 in Combination With PDR001 in Patients With Advanced Malignancies | NCT02807844 | Triple Negative... Pancreatic Carc... Melanoma Endometrial Car... | MCS110 PDR001 | 18 Years - | Novartis | |
| Dose Escalation Study of Vandetanib With Hypofractionated Stereotactic Radiotherapy in Recurrent Malignant Gliomas | NCT00822887 | Malignant Gliom... | Vandetanib Fractionated St... | 18 Years - | University of Colorado, Denver | |
| Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | NCT00968240 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
| Diagnostic Significance of CTCs in Patients With Thyroid Nodules (Circulating Tumor Cells) | NCT03772496 | Thyroid Nodule Diagnoses Disea... | circulating tum... Fine needle asp... | 18 Years - 70 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| AZD7451 for Recurrent Gliomas | NCT01468324 | Glioblastoma Mu... | AZD7451 | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | |
| Trial to Assess the Efficacy of a TCR Alfa Beta Depleted Graft in Pediatric Affected by ALL or AML and Receiving an HSCT | NCT01810120 | Acute Lymphobla... Leukemia Acute ... Non-Hodgkin Lym... Myelodysplastic... | TCR alfa beta T... | 3 Months - 20 Years | Bambino Gesù Hospital and Research Institute | |
| Using Pleural Effusions to Diagnose Cancer | NCT03319472 | Pleural Effusio... | 18 Years - | University of Patras | ||
| A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions | NCT00758316 | Malignant Pleur... | Thoracoscopy an... Thoracoscopy | 18 Years - | Singapore General Hospital | |
| A Phase 1/2 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK Pathway | NCT05578092 | Solid Tumor Advanced Solid ... Non Small Cell ... Colo-rectal Can... | MRTX0902 MRTX849 | 18 Years - | Mirati Therapeutics Inc. | |
| Study of TBX-3400 in Subjects With Solid Malignant Tumors Resistant or Refractory to Standard Therapies | NCT04640246 | Cancer Tumor, Solid Refractory Canc... | TBX-3400 | 18 Years - | Taiga Biotechnologies, Inc. | |
| DCE-MRI and DWI for Detection and Diagnosis of Breast Cancer | NCT02022579 | Breast Cancer BIRADS 3 BIRADS 4 BIRADS 5 | DCE-MRI and DWI | 18 Years - | American College of Radiology Imaging Network | |
| Study of TBX-3400 in Subjects With Solid Malignant Tumors Resistant or Refractory to Standard Therapies | NCT04640246 | Cancer Tumor, Solid Refractory Canc... | TBX-3400 | 18 Years - | Taiga Biotechnologies, Inc. | |
| A Phase I Study of Bi-Weekly rBBX-01 in Patients With Solid Tumors | NCT00869388 | Solid Tumors | rBBX-01 | 18 Years - | Washington University School of Medicine | |
| GastroIntestinal Cancer in Children and Adolescents | NCT05693519 | Gastrointestina... Colorectal Canc... Gastric Cancer Hepatoblastoma Hepatocellular ... Burkitt Lymphom... Neuroendocrine ... | 0 Years - 24 Years | Leiden University Medical Center | ||
| Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | NCT00968240 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
| Using Pleural Effusions to Diagnose Cancer | NCT03319472 | Pleural Effusio... | 18 Years - | University of Patras | ||
| Super-Selective Intraarterial Cerebral Infusion Of Temozolomide (Temodar) For Treatment Of Newly Diagnosed GBM And AA | NCT01180816 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
| Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma | NCT00535951 | Carcinoma, Non-... Mesothelioma | LBH589 | 18 Years - | Novartis | |
| Radiofrequency Ablation of Malignant Pulmonary Nodules | NCT02629978 | Neoplasms Carcinoma | CT-guided percu... | - | Chinese PLA General Hospital | |
| A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer | NCT00060944 | Liposarcoma Leiomyosarcoma | Yondelis Yondelis Dexamethasone Dexamethasone | 18 Years - | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | |
| Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors | NCT05728957 | Kidney Tumor Renal Benign Ne... Renal Malignant... | 18 Years - | Loyola University | ||
| Diagnostic Significance of CTCs in Patients With Thyroid Nodules (Circulating Tumor Cells) | NCT03772496 | Thyroid Nodule Diagnoses Disea... | circulating tum... Fine needle asp... | 18 Years - 70 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma | NCT03918252 | Mesothelioma | Nivolumab Injec... Ipilimumab Inje... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Phase II Trial for Large ER-Negative Breast Cancers | NCT01869192 | Malignant Neopl... | Epirubicin Cyclophosphamid... Docetaxel Capecitabine Radiation Thera... | 18 Years - | University of Colorado, Denver | |
| Patency of a Prototype Large Plastic Biliary Stent in the Palliation of Malignant Distal Biliary Strictures. | NCT01590394 | Stricture Obstruction Cancer | Large plastic b... | 18 Years - 85 Years | Mayo Clinic | |
| Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors | NCT05728957 | Kidney Tumor Renal Benign Ne... Renal Malignant... | 18 Years - | Loyola University | ||
| Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation | NCT05737706 | Solid Tumor Advanced Solid ... Non-small Cell ... Colo-rectal Can... Pancreatic Aden... | MRTX1133 | 18 Years - | Mirati Therapeutics Inc. | |
| Enzastaurin to Treat Recurrent Brain Tumor | NCT00108056 | Glioma | Enzastaurin (LY... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma | NCT01386710 | Glioblastoma Mu... Anaplastic Astr... | Bevacizumab and... Bevacizumab and... | 18 Years - | Northwell Health | |
| Safety and Effectiveness Study of Tumor Cell-derived Microparticles to Treat Malignant Ascites and Pleural Effusion | NCT01854866 | Malignant Pleur... Malignant Ascit... | Drug-packaging ... | 18 Years - 70 Years | Huazhong University of Science and Technology | |
| Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | NCT00968240 | Glioblastoma Mu... Anaplastic Astr... | Super-Selective... | 18 Years - | Northwell Health | |
| Safety Study of Increasing Doses of Combretastatin in Combination With Bevacizumab (Avastin) in Patients With Advanced Solid Tumors | NCT00395434 | Tumors | Combretastatin ... Bevacizumab (Av... | 18 Years - | Mateon Therapeutics | |
| Prospective Evaluation of Lymphoedema Among Patients With Gynaecological Cancer | NCT00604994 | Female Genital ... Ovarian Cancer Cervical Cancer Endometrial Can... Vulval Cancer | 18 Years - | Queensland Centre for Gynaecological Cancer | ||
| Efficacy Study of Pharmacokinetic(PK)/Pharmacodynamic(PD) Relationship of Monotherapy MORAb-004 in Metastatic Melanoma | NCT01335009 | Metastatic Mela... | MORAb-004 (mono... | 18 Years - | Eisai Inc. | |
| Study of Ramucirumab (IMC-1121B) Therapy and Corrected QT (QTc) Interval Changes | NCT01017731 | Cancer Solid Tumor | IMC-1121B Moxifloxacin Diphenhydramine | 18 Years - | Eli Lilly and Company | |
| Examination of Changes on Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS) in Patients Who Receive Gliadel Wafers During Initial Surgery for Glioblastoma Multiforme. Response or Failure to Gliadel Wafers for Subjects With Glioblastoma Multiforme. | NCT00645385 | Glioblastoma Mu... Anaplastic Astr... Anaplastic Olig... | MRS Spectroscop... | 18 Years - 85 Years | Weill Medical College of Cornell University | |
| Can Treatment With Bismuth Reduce Toxicity to Chemotherapy and Radiotherapy? | NCT00892502 | Hematological D... Hematological M... Blood Diseases Malignant Lymph... Leukemia Multiple Myelom... | Bismuth tablets Placebo tablets | 18 Years - 75 Years | Copenhagen University Hospital at Herlev | |
| The 'SILVERMAN1' Trial Single Incision Laparoscopic Versus Existing Resection (Minimal Access) for Neoplasia | NCT01319890 | Right Colon Tum... | Patients will b... | 18 Years - 85 Years | Irish Clinical Outcomes in Research and Education | |
| Study of the WallFlex™ Biliary Partially-covered Stent for the Palliative Treatment of Malignant Bile Duct Obstruction | NCT00713427 | Biliary Strictu... | WallFlex™ Bilia... | 18 Years - | Boston Scientific Corporation | |
| Genome Sequencing of Human Cancer Tissues | NCT02105545 | Cancer | Cancer Treatmen... | - | New Mexico Cancer Care Alliance | |
| LAM561 With RT and TMZ for Adults With Glioblastoma | NCT04250922 | Primary Gliobla... Glioblastoma Mu... | LAM561 TMZ RT | 18 Years - 75 Years | Laminar Pharmaceuticals | |
| LAM561 With RT and TMZ for Adults With Glioblastoma | NCT04250922 | Primary Gliobla... Glioblastoma Mu... | LAM561 TMZ RT | 18 Years - 75 Years | Laminar Pharmaceuticals | |
| Study of Patients With Stage IV Malignant Melanoma Using PS-341 (Bortezomib, Velcade) and Interferon-alpha-2b in Malignant Melanoma | NCT01462773 | Melanoma | Bortezomib Interferon Alfa... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Brentuximab Vedotin in CD30 Positive Epstein Barr Virus (EBV) Positive DLBCL of Elderly | NCT01671813 | Lymphoma | brentuximab ved... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute |
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