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Brief Title: Imipramine on ER+ve and Triple Negative Breast Cancer
Official Title: A Pre-Surgical Window of Opportunity Trial Investigating the Effect of Imipramine on Previously Untreated Breast Cancer (CTMS# 17-0037)
Study ID: NCT03122444
Brief Summary: Comparing changes in biomarkers from a diagnostic core needle biopsy to surgical pathology specimen or repeat core needle biopsy.
Detailed Description: This will be a single arm, non-randomized, pre-surgical clinical trial of women with newly diagnosed triple negative breast cancer comparing changes in biomarkers from a diagnostic core needle biopsy to surgical pathology specimen or repeat core needle biopsy.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Mays Cancer Center, UT Health San Antonio, San Antonio, Texas, United States
Name: Virginia G Kaklamani, MD
Affiliation: Principal Investigator
Role: PRINCIPAL_INVESTIGATOR