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Spots Global Cancer Trial Database for Dissecting the Pathways of Therapy Resistance in Early Breast Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Dissecting the Pathways of Therapy Resistance in Early Breast Cancer

Official Title: Dissecting the Pathways of Therapy Resistance in Early Breast Cancer: A Sub-study of the EORTC 10041/BIG 3-04 MINDACT Study

Study ID: NCT04995575

Conditions

Breast Cancer

Study Description

Brief Summary: Within the 1st step MINDACT patients who have already relapsed will be asked to participate. For these patients a biopsy of the metastasis should have been taken. A molecular analysis of the stored primary tumor sample and of the metastatic sample, using new technologies, will be performed, and the characteristics of both samples will be compared. Within the 2nd step a prospective collection of the metastasis samples will be implemented and analysis of biological material from relapsing MINDACT patients is foreseen. This process will provide insights on the biology of breast cancer and allow us to better understand mechanisms of resistance to therapies, contributing to overcoming this important problem.

Detailed Description:

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Onze Lieve Vrouw Ziekenhuis, Aalst, , Belgium

Institut Jules Bordet-Hopital Universitaire ULB, Brussels, , Belgium

Hopital De Jolimont, Haine-Saint-Paul, , Belgium

CHU-UCL Namur - CHU Site Sainte-Elisabeth-UCL Namur, Namur, , Belgium

Ziekenhuisgroep Twente - Twenteborg Ziekenhuis (3), Almelo, , Netherlands

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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