Spots Global Cancer Trial Database for metastasis
Every month we try and update this database with for metastasis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Standardization of Laparoscopic Surgery for Right Hemi Colon Cancer (SLRC) | NCT02942238 | Overall Surviva... Postoperative C... Metastasis Stage, Colon Ca... | CME D3 | 18 Years - 75 Years | Ruijin Hospital | |
| Ferumoxtran-10-enhanced MRI in Prostate Cancer Patients | NCT04261777 | Prostate Cancer Metastasis Prostatectomy | Ferrotran® (Fer... | 18 Years - | Saving Patients' Lives Medical B.V. | |
| Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC | NCT00313859 | Colorectal Canc... Metastasis | simvastatin | 18 Years - | Samsung Medical Center | |
| Pre- and Post-operative FOLFOX Based Therapy for Patients With Colorectal Cancer With Liver Involvement | NCT00537823 | Colorectal Canc... Metastases | Cetuximab Bevacizumab Leucovorin Oxaliplatin Fluorouracil | 18 Years - | Washington University School of Medicine | |
| De-escalation Chemotherapies Versus Escalation in Non Pre-treated Unresectable Patients With Metastatic Colorectal Cancer | NCT02842580 | Colorectal Neop... | 5 FLUOROURACYL acide folinique irinotecan Oxaliplatin capécitabine bevacizumab | 18 Years - | Federation Francophone de Cancerologie Digestive | |
| Predicting Tumor Metastasis by Employing a Target Organ/Primary Lesion Fusion Radiomics Model | NCT06202404 | Metastasis Predictive Canc... | 18 Years - 75 Years | Fudan University | ||
| Health Related Quality of Life After Surgery and Oncological Treatment of Colorectal Liver Metastases | NCT01587976 | Metastasis Quality of Life | - | Haukeland University Hospital | ||
| A Study of Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver | NCT01098422 | Colorectal Neop... Liver Neoplasms | Yttrium-90 Radi... | 18 Years - | University of California, San Diego | |
| A Safety Study of ZD4054 in Prior Chemotherapy Treated Patients With Metastatic Hormone-resistant Prostate Cancer | NCT01000948 | Prostate Cancer Metastasis | ZD4054 | 18 Years - 90 Years | Aarhus University Hospital | |
| Pembrolizumab + Idelalisib for Lung Cancer Study | NCT03257722 | Non Small Cell ... Metastasis Recurrence | Pembrolizumab Idelalisib | 18 Years - | Augusta University | |
| Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer | NCT05095207 | Breast Cancer Metastasis | Abemaciclib Bicalutamide | 18 Years - 90 Years | Icahn School of Medicine at Mount Sinai | |
| Liver Transplantation for Unresectable GIST Liver Metastases | NCT04825470 | Liver Diseases Liver Cancer Liver Metastase... Liver Neoplasms Liver Mass Liver Carcinoma Liver Transplan... Liver Transplan... GIST GIST, Malignant Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Metastases to L... Metastatic Live... Metastasis Metastases Liver Transplan... Transplant Onco... | Liver Transplan... | 18 Years - | Hospital Universitario Virgen de la Arrixaca | |
| Gleevec Administered Preoperatively to Reduce Gastrointestinal Stromal Tumor (GIST) | NCT00290485 | Gastrointestina... | Imatinib mesyla... | 18 Years - | Maisonneuve-Rosemont Hospital | |
| Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal Therapy | NCT02711007 | Osteosarcoma Metastasis | apatinib | 16 Years - | Peking University People's Hospital | |
| De-escalation Chemotherapies Versus Escalation in Non Pre-treated Unresectable Patients With Metastatic Colorectal Cancer | NCT02842580 | Colorectal Neop... | 5 FLUOROURACYL acide folinique irinotecan Oxaliplatin capécitabine bevacizumab | 18 Years - | Federation Francophone de Cancerologie Digestive | |
| Adrenalectomy for Solitary Adrenal Gland Metastases | NCT01135238 | Adrenal Gland M... Adrenalectomy | - | Mayo Clinic | ||
| Comparison Between LDCT With DL Recontruction and Standard Dose CT | NCT05324046 | Liver Metastase... | contrast-enhanc... | 20 Years - 85 Years | Seoul National University Hospital | |
| Targeted Therapy Selection Based on Tumor Tissue Kinase Activity Profiles for Patients With Advanced Solid Malignancies, an Exploratory Study | NCT01190241 | Advanced Solid ... Inoperable Metastasis | desatinib or su... | 18 Years - | Amsterdam UMC, location VUmc | |
| Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery | NCT01798771 | Primary Maligna... Glioma Glioblastoma Metastasis | Interventional ... Control arm | 18 Years - | Johann Wolfgang Goethe University Hospital | |
| Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver | NCT02885753 | Colorectal Neop... | Oxaliplatin int... 5 FU bolus Folinic acid Oxaliplatin int... Panitumumab Bevacizumab 5 FU continuous Irinotecan | 18 Years - | Federation Francophone de Cancerologie Digestive | |
| The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma | NCT00302562 | Laryngeal Cance... Hypopharyngeal ... | 30 Years - 75 Years | National Taiwan University Hospital | ||
| Palliative Radiation Oncology Chief's Clinic | NCT03995927 | Malignant Disea... Metastasis | Data collection... Quality of Life... | 18 Years - | Wake Forest University Health Sciences | |
| Liver Transplantation for Unresectable GIST Liver Metastases | NCT04825470 | Liver Diseases Liver Cancer Liver Metastase... Liver Neoplasms Liver Mass Liver Carcinoma Liver Transplan... Liver Transplan... GIST GIST, Malignant Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Metastases to L... Metastatic Live... Metastasis Metastases Liver Transplan... Transplant Onco... | Liver Transplan... | 18 Years - | Hospital Universitario Virgen de la Arrixaca | |
| Pretreatment With HCQ Before Radiotherapy and Chemotherapy in Advanced NPC Patients | NCT06389201 | Nasopharyngeal ... | HCQ Placebo | 20 Years - 70 Years | Affiliated Hospital of Nantong University | |
| Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer | NCT01283789 | Metastatic Brea... | Lapatinib and R... | 18 Years - | University of Kansas Medical Center | |
| Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma | NCT01091883 | Bone Cancer Bone Metastases Pain | Exablate treatm... Radiation | 18 Years - | InSightec | |
| Clinical and Functional Variables in Oncology | NCT03879096 | Cancer, Metasta... Cancer Survivorship | Therapeutic Exe... | 18 Years - 80 Years | University of Malaga | |
| Study of PAT in Patients With Solid Tumor Cancers | NCT05338658 | Metastasis Solid Tumor | Peptide Alarm T... | 18 Years - | Masonic Cancer Center, University of Minnesota | |
| First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy | NCT00389155 | Bladder Cancer Transitional Ce... Metastasis | Vinflunine Gemcitabine Placebo | 18 Years - | Bristol-Myers Squibb | |
| A Study Investigating the Safety and Tolerability of an Immune Treatment in Cancer Patients With Lesions to the Skin | NCT04059588 | Cancer Solid Tumor Cancer of Skin | 2141 V-11 | 18 Years - | Rockefeller University | |
| Etiology of the Platelet-Cancer Metastatic Pathway - A Study of Inflammatory Markers, Platelet Characteristics and Metastatic Surrogates in Cancer Patients and Controls | NCT02450175 | Neoplasm | Everolimus Letrozole | 18 Years - | Sinai Hospital of Baltimore | |
| Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells | NCT01022723 | Cancer | - | National Cancer Centre, Singapore | ||
| Evaluation of the Predictive and Prognostic Value of Germ-line Polymorphisms in Patients With Metastatic Breast Cancer | NCT01460186 | Breast Cancer Metastasis | Blood sample fo... | 18 Years - | Centre Leon Berard | |
| ECI301 and Radiation for Advanced or Metastatic Cancer | NCT01441115 | Cancer Neoplasm Metast... Radiation Oncol... Neoplasm Metastasis | Radiation Thera... ECI301 | 18 Years - 99 Years | National Institutes of Health Clinical Center (CC) | |
| N-of-1 Trial: Actionable Target Identification in Metastatic Cancer for Palliative Systemic Therapy | NCT02142036 | Metastatic Canc... | EMA-approved AT... | 18 Years - | Oslo University Hospital | |
| Safety and Preliminary Efficacy of SBRT in Patients With Metastatic RCC Treated With Targeted or IO Therapy | NCT02864615 | Metastatic Rena... | SBRT | 18 Years - 75 Years | Kidney Cancer Research Bureau | |
| Prevalence of the Mutational Status of V-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) in Metastatic Colorectal Cancer (mCRC) in Argentine Patients | NCT01082757 | Colorectal Neop... | 22 Years - | Merck KGaA, Darmstadt, Germany | ||
| Chemotherapy and Surgical Resection in Patients With Hepatic Oligometastatic Adenocarcinoma of the Pancreas | NCT04617457 | Pancreatic Canc... Metastasis Surgery Oligometastatic... | nal-irinotecan ... | 18 Years - | University of Cologne | |
| Monotherapy With Eribulin In Her2 Negative Metastatic Breast Cancer as a First Line Treatment | NCT02061085 | Breast Neoplasm Metastasis | Eribulina | 18 Years - | MedSIR | |
| A Study of BIO-11006 in the Treatment of Advanced Non-Small Cell Lung Cancer | NCT03472053 | Non Small Cell ... | BIO-11006 plus ... Standard of Car... | 18 Years - 70 Years | BioMarck Pharmaceuticals, Ltd. | |
| Standard Palliative Care Versus Standard Palliative Care Plus Polychemotherapy in Metastasized Malignant Melanoma | NCT00226473 | Metastatic Mela... | Cisplatin, Vind... | 18 Years - 75 Years | Dermatologic Cooperative Oncology Group | |
| EndoTAG-1 / Gemcitabine Combination Therapy to Treat Locally Advanced and/or Metastatic Adenocarcinoma of the Pancreas | NCT00377936 | Adenocarcinoma Metastasis Pancreas Neopla... | Gemcitabine alo... EndoTAG-1 and G... EndoTAG-1 and G... EndoTAG-1 and G... | 18 Years - | MediGene | |
| Encorafenib, Binimetinib and Palbociclib in BRAF-mutant Metastatic Melanoma CELEBRATE | NCT04720768 | Melanoma Metastasis | Binimetinib Encorafenib Palbociclib | 18 Years - 100 Years | Peter MacCallum Cancer Centre, Australia | |
| First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy | NCT00389155 | Bladder Cancer Transitional Ce... Metastasis | Vinflunine Gemcitabine Placebo | 18 Years - | Bristol-Myers Squibb | |
| Etiology of the Platelet-Cancer Metastatic Pathway - A Study of Inflammatory Markers, Platelet Characteristics and Metastatic Surrogates in Cancer Patients and Controls | NCT02450175 | Neoplasm | Everolimus Letrozole | 18 Years - | Sinai Hospital of Baltimore | |
| Sentinel Lymph Node (SLN) in Colorectal Carcinoma (CRC) With a Near-infrared (NIR)-Dye | NCT02122523 | Sentinel Lymph ... Colorectal Canc... Metastasis | Near-Infrared (... | 18 Years - | Amsterdam UMC, location VUmc | |
| Using Imaging Data and Genomic Data to Predict Metastasis of Breast Cancer After Treatment | NCT03941639 | Breast Cancer | - | Chinese University of Hong Kong | ||
| Prognostic Role of Free Psa Ratio at Biochemical Recurrence After Radical Treatments for Prostate Cancer | NCT03927287 | Metastasis Castration-resi... Death | Free PSA ratio ... | 18 Years - | Rabin Medical Center | |
| A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK114 | NCT05200273 | Advanced or Met... Malignancy Metastasis | AK114 | 18 Years - | Akeso | |
| Contribution of the Imaging to the Expression of intégrines αvβ3 for the Characterization of Residual Masses of Non-seminoma Tumors at the End of Chemotherapy | NCT02317393 | Non-seminomatou... Metastasis | K5-RGD PET FDG | 18 Years - | Centre Francois Baclesse | |
| Preclinical Validation of New Anti-melanoma Compounds | NCT03798977 | Melanoma | 18 Years - | Centre Hospitalier Universitaire de Nice | ||
| Study and Modulation of Immune Responses in Primary and Metastatic Colon Cancers | NCT06435689 | Colon Cancer Peritoneal Carc... | Sampling | 18 Years - | Assistance Publique - Hôpitaux de Paris | |
| Hepatic Artery Infusion With Oxaliplatin | NCT00244348 | Colorectal Canc... Metastasis Liver Cancer | Oxaliplatin (vi... 5 Fluorouracil ... | 18 Years - | Medical College of Wisconsin | |
| Exploration of Circulating VE-cadherin in Metastatic Colorectal Adenocarcinoma Patients Treated With Bevacizumab | NCT01405430 | Colorectal Canc... Metastasis | Bevacizumab + b... | 18 Years - | Centre Leon Berard | |
| ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain | NCT00981578 | Bone Metastases | ExAblate 2100 | 18 Years - | InSightec | |
| A Pilot Study to Explore Serum and Imaging Biomarkers in Patients With Spinal Cord Compression | NCT00928382 | Cancer Spine Metastasi... | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | ||
| SUPERvised Three-month Exercise Program in MEN With Prostate cAncer Receiving Androgen-deprivaTioN thERapy | NCT06282185 | Prostatic Neopl... Metastasis | Physiotherapy | 18 Years - 85 Years | Canisius-Wilhelmina Hospital | |
| Prognostic Value of CTC in HNSCC Patients | NCT01884129 | Recurrence Metastasis Death | 20 Years - | Chang Gung Memorial Hospital | ||
| The Role of SDF-1/CXCR4 in Metastasis of Oral Squamous Cell Carcinoma | NCT00173849 | Oral Cancer | 30 Years - 75 Years | National Taiwan University Hospital | ||
| Assessment of Pain and Quality of Life in Breast and Prostate Cancer Patients With Bone Metastases | NCT00434317 | Neoplasm Metast... | Zoledronic acid | 18 Years - | Novartis | |
| Efficacy of Activated Lymphocytes in Renal Cell Carcinoma. | NCT00151645 | Metastatic Rena... | activated lymph... | 18 Years - 70 Years | Rennes University Hospital | |
| Effect of Colchicine for the Palliative Management of Hepatocellular Carcinoma | NCT01935700 | Hepatocellular ... Metastasis Invasion | Colchicine | 20 Years - 90 Years | Kaohsiung Medical University Chung-Ho Memorial Hospital | |
| Same-session MR-only Simulation and Treatment With MRI-guided Adaptive Palliative RadioTherapy | NCT03824366 | Malignancy Metastasis Hemoptysis Gastrointestina... Pelvic Bleeding Superior Vena C... Mediastinal Dis... | Volumetric MR i... Radiation thera... | 18 Years - | Washington University School of Medicine | |
| IGFBP-3 in Ovarian Cancer Invasion | NCT00154986 | Ovarian Carcino... | immunohistochem... | 21 Years - 80 Years | National Taiwan University Hospital | |
| Real World Evidence Study on Metastatic Prostate Cancer in the Pirkanmaa Hospital District in Finland | NCT05701007 | Metastatic Cast... Metastatic Cast... | abiraterone enzalutamide docetaxel apalutamide cabazitaxel Radium-223 Lutetium-177 degarelix goserelin leuprorelin triptorelin | 18 Years - | Pfizer | |
| Metastatic Colorectal Cancer: Treatment Response With Dynamic Contrast MRI | NCT00820456 | Colorectal Neop... Hepatic Neoplas... | DCE-MRI | 18 Years - | American College of Radiology | |
| Acupuncture for Shortness of Breath in Cancer Patients | NCT00067691 | Lung Neoplasms Breast Neoplasm... | Acupuncture | 18 Years - | National Center for Complementary and Integrative Health (NCCIH) | |
| Apatinib Monotherapy Versus Apatinib Combined With Camrelizumab for Third-line Treatment of Metastatic Gastric Cancer | NCT05095636 | Gastric Cancer Metastasis | Apatinib Mesyla... Camrelizumab | 18 Years - 75 Years | Fudan University | |
| Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases | NCT05023772 | Neoplasm Metast... Spinal Cord Dis... Spinal Cord Com... Spinal Cord Tum... Spine Metastase... | Stereotactic La... Stereotactic Ra... MRI guided lase... | 18 Years - | Henry Ford Health System | |
| Capecitabine to Prevent Recurrence of Hepatocellular Carcinoma After Curative Resection | NCT00561522 | Hepatocellular ... Neoplasm Metast... | Capecitabine No other preven... | 18 Years - 79 Years | Fudan University | |
| Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery | NCT05028400 | Aneurysm AVM Dural Arteriove... Glioma Meningioma Metastasis | Laser speckle c... | 18 Years - | Insel Gruppe AG, University Hospital Bern | |
| Resection vs no Resection of the Primary in Colorectal Cancer With Unresectable Metastases | NCT02015923 | Colonic Cancer Unresectable Me... | Colonic resecti... Chemotherapy- s... | 18 Years - | Hospital Universitari de Bellvitge | |
| A Study of Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver | NCT01098422 | Colorectal Neop... Liver Neoplasms | Yttrium-90 Radi... | 18 Years - | University of California, San Diego | |
| Study of the Safety and Pharmacokinetics of Olaratumab (IMC-3G3) in Japanese Participants With Solid Tumors | NCT01199822 | Malignancy Metastasis | Olaratumab | 20 Years - | Eli Lilly and Company | |
| The Effects of General Anesthetics on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and Mechanism Involved | NCT03193710 | Colorectal Canc... Survival Rate General Anesthe... Lymphocyte Dest... Molecular Mecha... | Propofol Sevoflurane Remifentanil | 18 Years - 65 Years | West China Hospital | |
| PET-CT and Circulating Tumor Cells in Colorectal Cancer | NCT01163305 | Colorectal Canc... Metastasis | Chemotherapy | 18 Years - | Chinese University of Hong Kong | |
| A Study Evaluating Safety and Therapeutic Activity of THOR-707 in Adult Subjects With Advanced or Metastatic Solid Tumors (THOR-707-101) | NCT04009681 | Metastasis | THOR-707 Checkpoint inhi... anti-EGFR antib... | 18 Years - | Synthorx, Inc, a Sanofi company | |
| Study of Dasatinib (BMS-354825) in Patients With Advanced Estrogen/Progesterone Receptor-positive (ER+/PR+) or Her2/Neu-positive (Her2/Neu+)Breast Cancer | NCT00371345 | Breast Cancer Metastasis | Dasatinib Dasatinib 100 m... | 18 Years - | Bristol-Myers Squibb | |
| CEST- Glucose Enhanced MRI for Metastatic Brain Tumours | NCT02796729 | Brain Neoplasms... Metastasis | Magnetic resona... Gadovist (Gadob... 50% dextrose so... | 18 Years - 65 Years | British Columbia Cancer Agency | |
| Encorafenib, Binimetinib and Palbociclib in BRAF-mutant Metastatic Melanoma CELEBRATE | NCT04720768 | Melanoma Metastasis | Binimetinib Encorafenib Palbociclib | 18 Years - 100 Years | Peter MacCallum Cancer Centre, Australia |
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