Spots Global Cancer Trial Database for Onco-Genomas Brasil: Mapping Breast and Prostate Cancer in the Brazilian Public Health System
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Trial Identification
Brief Title: Onco-Genomas Brasil: Mapping Breast and Prostate Cancer in the Brazilian Public Health System
Official Title: Onco-Genomas Brasil: Mapping Breast and Prostate Cancer in the Brazilian Public Health System
Study ID: NCT05306600
Interventions
Study Description
Brief Summary: This project aims to perform complete sequencing of the somatic (tumor) and germline exomes during clinical investigation of cancer patients treated through the Brazilian Unified Health System to generate genomic and phenotypic data for the Brazilian Ministry of Health's National Precision Genomics and Health Program, called Genomas Brasil, as well as to collect data on the population's ancestry.
Detailed Description: In Brazil, the most frequent types of neoplasm are prostate cancer in men and breast cancer in women. Understanding the molecular variants in tumors, which result from mutations and variants that occur during carcinogenesis, can affect treatment response and disease prognosis and is an important target of oncology research. Detecting hereditary genetic syndromes also helps in oncological follow-up, allowing prediction of the risk of new neoplasms. This project aims to perform complete sequencing of the somatic (tumor) and germline exomes during clinical investigation of cancer patients treated through the Brazilian Unified Health System to generate genomic and phenotypic data for the Brazilian Ministry of Health's National Precision Genomics and Health Program, called Genomas Brasil, as well as to collect data on the population's ancestry.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Hospital Universitário Getúlio Vargas, Manaus, Amazonas, Brazil
Hospital Calixto Midlej Filho/ Santa Casa de Itabuna, Itabuna, Bahia, Brazil
Hospital Santa Rita de Cássia - AFECC, Vitória, Espírito Santo, Brazil
Hospital do Câncer do Maranhão, São Luís, Maranhão, Brazil
Hospital da Santa Casa de Misericórdia, Belo Horizonte, Minas Gerais, Brazil
Hospital das Clínicas, Belo Horizonte, Minas Gerais, Brazil
Hospital do Câncer/União Oeste Paranaense de Estudo e Combate ao Câncer, Cascavel, Paraná, Brazil
Hospital Universitário João de Barros Barreto, Belém, Pará, Brazil
Liga Norte Riograndense Contra o Câncer, Natal, Rio Grande Do Norte, Brazil
Hospital Escola da Universidade Federal de Pelotas, Pelotas, Rio Grande Do Sul, Brazil
Hospital do Amor, Barretos, São Paulo, Brazil
Hospital Universitário Maria Aparecida Pedrossian, Campo Grande, , Brazil
Hospital Araújo Jorge, Goiânia, , Brazil
Hospital de Clínicas de Porto Alegre, Porto Alegre, , Brazil
Hospital São Lucas da PUCRS, Porto Alegre, , Brazil
Grupo Hospitalar Conceição, Porto Alegre, , Brazil
Hospital Fêmina, Porto Alegre, , Brazil
Hospital São Camilo, São Paulo, , Brazil
Hospital Universitário Cassiano Antônio de Moraes, Vitória, , Brazil
Contact Details
Name: Daniela D Rosa, PhD
Affiliation: Hospital Moinhos de Vento
Role: PRINCIPAL_INVESTIGATOR
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