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Brief Title: Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.
Official Title: A Phase I/Ib, Open-label, Multi-center Dose Escalation Study of NIS793 in Combination With PDR001 in Adult Patients With Advanced Malignancies
Study ID: NCT02947165
Brief Summary: To characterize the safety and tolerability of NIS793 as single agent and in combination with PDR001 and to identify recommended doses for future studies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Sarah Cannon Research Institute SC, Nashville, Tennessee, United States
Huntsman Cancer Institute SC, Salt Lake City, Utah, United States
Novartis Investigative Site, Salzburg, , Austria
Novartis Investigative Site, Toronto, Ontario, Canada
Novartis Investigative Site, Ulm, , Germany
Novartis Investigative Site, Wuerzburg, , Germany
Novartis Investigative Site, Hong Kong, , Hong Kong
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Rozzano, MI, Italy
Novartis Investigative Site, Kashiwa, Chiba, Japan
Novartis Investigative Site, St. Gallen, , Switzerland
Novartis Investigative Site, Taipei, , Taiwan
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR