Spots Global Cancer Trial Database for hepatocellular cancer
Every month we try and update this database with for hepatocellular cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Effect of Remote Ischaemic preConditioning on Liver Injury in Patients Undergoing LIVER Resection Surgery | NCT03594929 | Hepatocellular ... | Active RIC Sham Control | 21 Years - | Singapore General Hospital | |
| A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors | NCT03517488 | Melanoma Breast Carcinom... Hepatocellular ... Urothelial Carc... Squamous Cell C... Renal Cell Carc... Colorectal Carc... Non-small Cell ... Gastric or Gast... Endometrial Car... Mesothelioma Neuroendocrine ... Cervical Cancer Small Cell Lung... Squamous Cell C... Castration-Resi... Nasopharyngeal ... Cholangiocarcin... Basal Cell Carc... Ovarian Carcino... Fallopian Tube ... Thymoma Thymic Carcinom... Squamous Cell C... Vulvar Carcinom... Solid Tumors Wi... Malignant Adnex... Non-squamous Ce... | XmAb20717 | 18 Years - | Xencor, Inc. | |
| Study of Pazopanib and Ixabepilone in Patients With Solid Tumors | NCT01012362 | Breast Cancer Lung Cancer Colon Cancer Pancreatic Canc... Head and Neck C... Kidney Cancer Sarcoma Hepatocellular ... | Pazopanib Ixabepilone | 18 Years - | Masonic Cancer Center, University of Minnesota | |
| Survey of Cabozantinib Tablets Used To Treat People With Hepatocellular Carcinoma | NCT05100082 | Hepatocellular ... | Cabozantinib | - | Takeda | |
| Prospective Observational Trial to Evaluate Quality of Life After Stereotactic Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma | NCT03253536 | Hepatocellular ... Quality of Life Stereotactic Bo... Observational | observational | 18 Years - | Ludwig-Maximilians - University of Munich | |
| Prospective Observational Trial to Evaluate Quality of Life After Stereotactic Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma | NCT03253536 | Hepatocellular ... Quality of Life Stereotactic Bo... Observational | observational | 18 Years - | Ludwig-Maximilians - University of Munich | |
| GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Hepatocellular Carcinoma (HCC) | NCT05003895 | Hepatocellular ... Hepatocellular ... Metastatic Hepa... | Cyclophosphamid... CAR-T cell Fludarabine | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Transarterial Chemoembolization in Combination With Nivolumab Performed for Intermediate Stage Hepatocellular Carcinoma | NCT03572582 | Carcinoma, Hepa... Hepatic Carcino... Hepatocellular ... | Nivolumab TACE | 18 Years - | AIO-Studien-gGmbH | |
| Adult-to-Adult Living Donor Transplant Cohort Study | NCT01619475 | Liver Diseases Hepatocellular ... End Stage Liver... Hepatitis C Liver Cirrhosis | 18 Years - | Arbor Research Collaborative for Health | ||
| Volatile Organic Compounds for the Assessment of Liver Disease | NCT04620538 | Cirrhosis Cirrhosis, Live... Fibrosis, Liver Hepatocellular ... Hepatocellular ... | Breath Analysis | 18 Years - 90 Years | Imperial College London | |
| A Phase 1/2 Study to Evaluate OTX-2002 in Patients With Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association With the MYC Oncogene | NCT05497453 | Hepatocellular ... Solid Tumor Hepatocellular ... Hepatocellular ... Hepatocellular ... Liver Cancer Liver, Cancer o... | OTX-2002 Tyrosine kinase... Tyrosine kinase... Checkpoint Inhi... | 18 Years - | Omega Therapeutics | |
| Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer | NCT03037437 | Hepatocellular ... | Sorafenib (SOR) Hydroxychloroqu... | 18 Years - 100 Years | The University of Texas Health Science Center at San Antonio | |
| Study of Microwave Spherical Ablation and Traditional Microwave Ablation in Single Hepatocellular Carcinoma ≤5cm | NCT05361538 | Hepatocellular ... Microwave Ablat... Microwave Spher... Prognosis | True circular m... | 18 Years - 75 Years | Tianjin Third Central Hospital | |
| Sorafenib + mFOLFOX for Hepatocellular Carcinoma | NCT01775501 | Hepatocellular ... | Leucovorin Fluorouracil Oxaliplatin Sorafenib | 18 Years - | Massachusetts General Hospital | |
| HCC Patient Preferences in Japan | NCT02616692 | Hepatocellular ... | Hepatocellular ... | 20 Years - | Bayer | |
| Interest of elastoFRM With Force Measure by MRI on Patients With Hepatocellular Cancer | NCT02929082 | Hepatocellular ... | IRM with a 5-mi... | 18 Years - | Assistance Publique - Hôpitaux de Paris | |
| Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow | NCT03551951 | Non Small Cell ... Esophageal Canc... Gastric Cancer Pancreatic Canc... Hepatocellular ... Colorectal Canc... | Test for circul... | 18 Years - | University of Missouri-Columbia | |
| A Pilot Study of "OncozeneTM" Microspheres for Intra-arterial Delivery of Doxorubicin | NCT02141906 | Hepatocellular ... | Oncozene-DEB-TA... | 18 Years - | University of Texas Southwestern Medical Center | |
| Comparing the Diagnostic Efficiencies of CEUS and EOB-MRI in Patients With High Risk of HCC | NCT04212286 | Hepatocellular ... Liver Cirrhoses Diagnoses Disea... | Diagnostic CEUS... | 18 Years - 80 Years | Tianjin Third Central Hospital | |
| Measuring and Improving the Safety of Test Result Follow-Up | NCT04166240 | Lung Cancer Breast Cancer Colon Cancer Bladder Cancer Hepatocellular ... | SAFER TRACKS In... | 18 Years - 65 Years | VA Office of Research and Development | |
| Sorafenib Concomitantly Used With TACE (Transarterial Chemoembolization) in uHCC (Unresectable Hepatocellular Carcinoma) Patients in China | NCT01839630 | Carcinoma, Hepa... | Sorafenib (Nexa... | - | Bayer | |
| The PLATON Network | NCT05489250 | Hepatocellular ... Cholangiocarcin... Gallbladder Can... Pancreatic Canc... Oesophageal Can... Stomach Cancer | 18 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | ||
| Study of Safety and Tolerability of PDR001 in Combination With Sorafenib and to Identify the Maximum Tolerated Dose and/or Phase 2 Dose for This Combination in Advanced Hepatocellular Patients | NCT02988440 | Hepatocellular ... | PDR001 Sorafenib | 18 Years - | Novartis | |
| Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED) | NCT05451043 | Pancreatic Canc... Hepatocellular ... Biliary Tract C... Cholangiocarcin... | Durvalumab Gemcitabine Nab paclitaxel Tremelimumab Propranolol Cisplatin | 18 Years - | AHS Cancer Control Alberta | |
| Trial of Sorafenib in Hepatocellular Cancer (HCC) Transplant Patients | NCT00997022 | Hepatocellular ... | Sorafenib | 18 Years - | Columbia University | |
| Study of Safety and Tolerability of PDR001 in Combination With Sorafenib and to Identify the Maximum Tolerated Dose and/or Phase 2 Dose for This Combination in Advanced Hepatocellular Patients | NCT02988440 | Hepatocellular ... | PDR001 Sorafenib | 18 Years - | Novartis | |
| Autologous Natural Killer T Cells Infusion for the Treatment of Cancer | NCT01801852 | Breast Cancer Glioma Hepatocellular ... Squamous Cell L... Pancreatic Canc... Colon Cancer Prostate Cancer | NKT cells | 18 Years - 90 Years | Chinese PLA General Hospital | |
| Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver | NCT03151213 | Hepatocellular ... | Pregabalin 150m... Placebo | 18 Years - 75 Years | Tanta University | |
| Diagnostic Efficacies of Sonazoid-CEUS and EOB-MRI in Patients With High Risk of HCC | NCT04212273 | Hepatocellular ... Liver Cirrhoses Diagnoses Disea... | Diagnostic Sona... | 18 Years - 80 Years | Tianjin Third Central Hospital | |
| Vascular Invasion Signatures in cfDNA Support Re-staging of Liver Cancer | NCT05540925 | Carcinoma, Hepa... Hepatocellular ... Liver Cancer | Liver resection | 25 Years - 75 Years | Eastern Hepatobiliary Surgery Hospital | |
| Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer or Hepatic Metastases | NCT00465023 | Hepatocellular ... Cholangiocarcin... Hepatic Metasta... | Proton Beam Rad... | 18 Years - | Massachusetts General Hospital | |
| Effect of Remote Ischaemic preConditioning on Liver Injury in Patients Undergoing LIVER Resection Surgery | NCT03594929 | Hepatocellular ... | Active RIC Sham Control | 21 Years - | Singapore General Hospital | |
| A Study of Individualized Stereotactic Body Radiation Therapy (SBRT) for Intrahepatic Cancer | NCT01522937 | Liver Cancer Hepatocellular ... | individualized ... | 18 Years - | University of Michigan Rogel Cancer Center | |
| Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer | NCT03037437 | Hepatocellular ... | Sorafenib (SOR) Hydroxychloroqu... | 18 Years - 100 Years | The University of Texas Health Science Center at San Antonio | |
| A Randomized Phase II Trial of Surgery Plus Sorafenib vs. Sorafenib Alone for Hepatocellular Cancer (HCC) With Portal Vein Invasion | NCT03971201 | Hepatocellular ... | hepatic resecti... Sorafenib | 18 Years - | White Plains Hospital | |
| AFPᶜ³³²T in Advanced HCC | NCT03132792 | Hepatocellular ... AFP Expressing ... | Autologous gene... | 18 Years - 75 Years | Adaptimmune | |
| Measuring and Improving the Safety of Test Result Follow-Up | NCT04166240 | Lung Cancer Breast Cancer Colon Cancer Bladder Cancer Hepatocellular ... | SAFER TRACKS In... | 18 Years - 65 Years | VA Office of Research and Development | |
| Immunization With AFP + GM CSF Plasmid Prime and AFP Adenoviral Vector Boost in Patients With Hepatocellular Carcinoma | NCT00669136 | Hepatocellular ... Hepatoma Liver Cancer, A... Liver Cell Carc... Liver Cell Carc... Cancer of Liver Cancer of the L... Cancer, Hepatoc... Hepatic Cancer Hepatic Neoplas... Hepatocellular ... Liver Cancer Neoplasms, Hepa... Neoplasms, Live... | AFP + GM-CSF Pl... | 18 Years - 80 Years | University of Pittsburgh | |
| T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer | NCT01967823 | Melanoma Meningioma Breast Cancer Non-Small Cell ... Hepatocellular ... | Anti-NY ESO-1 m... Cyclophosphamid... Fludarabine Aldesleukin | 15 Years - 70 Years | National Institutes of Health Clinical Center (CC) | |
| Treatment of Unresectable Hepatocellular Cancer With Opioid Growth Factor | NCT00706576 | Hepatocellular ... | Infusion of opi... | 18 Years - | University of Missouri-Columbia | |
| Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver | NCT03151213 | Hepatocellular ... | Pregabalin 150m... Placebo | 18 Years - 75 Years | Tanta University | |
| AFPᶜ³³²T in Advanced HCC | NCT03132792 | Hepatocellular ... AFP Expressing ... | Autologous gene... | 18 Years - 75 Years | Adaptimmune | |
| LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment With Transarterial Embolization (TAE) Alone or Combined With Thermal Ablation | NCT02649868 | Hepatic Cancer Liver Neoplasms Hepatocellular ... Liver Cancer | TAE RFA LC Bead LUMI | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | |
| Comparing the Diagnostic Efficiencies of CEUS and EOB-MRI in Patients With High Risk of HCC | NCT04212286 | Hepatocellular ... Liver Cirrhoses Diagnoses Disea... | Diagnostic CEUS... | 18 Years - 80 Years | Tianjin Third Central Hospital | |
| Perioperative Palliative Care Surrounding Cancer Surgery for Patients & Their Family Members | NCT03611309 | Gastrointestina... | Surgeon-palliat... Surgeon team al... | 18 Years - | Stanford University | |
| Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma | NCT03937830 | Hepatocellular ... Hepatocellular ... Metastatic Hepa... | durvalumab Doxorubicin-Elu... TACE bevacizumab Tremelimumab | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Clinical Trial Comparing TACE With TACE + SABR in Stage BCLC B HCC (HepSTAR) | NCT02958163 | Liver Neoplasms Hepatocellular ... | Trans-arterial ... Doxorubicin Stereotactic Ab... | 18 Years - | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | |
| TRC105 for Liver Cancer That Has Not Responded to Sorafenib | NCT01375569 | Hepatocellular ... Hepatocellular ... Carcinoma, Hepa... | TRC105 | 18 Years - 80 Years | National Institutes of Health Clinical Center (CC) | |
| Profile of Soluble and Cellular Biomarkers and of Functional Imaging During Antiangiogenic Therapies in Cancer Patients | NCT01507740 | Hepatocellular ... Non-small Cell ... Renal Cell Canc... Colorectal Canc... | Avastin Suntent Nexavar | 18 Years - | Medical University Innsbruck | |
| GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Hepatocellular Carcinoma (HCC) | NCT05003895 | Hepatocellular ... Hepatocellular ... Metastatic Hepa... | Cyclophosphamid... CAR-T cell Fludarabine | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Drug Monitoring of Sorafenib in Patients With Advanced Hepatocellular Carcinoma | NCT01078311 | Hepatocellular ... | 18 Years - | South West Sydney Local Health District | ||
| Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer or Hepatic Metastases | NCT00465023 | Hepatocellular ... Cholangiocarcin... Hepatic Metasta... | Proton Beam Rad... | 18 Years - | Massachusetts General Hospital | |
| High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors | NCT04033107 | Hepatocellular ... Pancreatic Canc... Gastric Cancer Colorectal Canc... | Vitamin C Metformin | 18 Years - 70 Years | Zhongnan Hospital | |
| Study of PF-07263689 in Participants With Selected Advanced Solid Tumors | NCT05061537 | Renal Cell Canc... Melanoma Non-Small-Cell ... Hepatocellular ... Bladder Cancer Sarcoma Head and Neck C... Colorectal Canc... Ovarian Cancer Squamous Cell C... | PF-07263689 Sasanlimab | 18 Years - | Pfizer | |
| Immunization With AFP + GM CSF Plasmid Prime and AFP Adenoviral Vector Boost in Patients With Hepatocellular Carcinoma | NCT00669136 | Hepatocellular ... Hepatoma Liver Cancer, A... Liver Cell Carc... Liver Cell Carc... Cancer of Liver Cancer of the L... Cancer, Hepatoc... Hepatic Cancer Hepatic Neoplas... Hepatocellular ... Liver Cancer Neoplasms, Hepa... Neoplasms, Live... | AFP + GM-CSF Pl... | 18 Years - 80 Years | University of Pittsburgh | |
| The PLATON Network | NCT05489250 | Hepatocellular ... Cholangiocarcin... Gallbladder Can... Pancreatic Canc... Oesophageal Can... Stomach Cancer | 18 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | ||
| Investigation of Immune Modulation by Modern Acupuncture in Gastroenterologic Cancers | NCT04692454 | Hepatocellular ... Gastrointestina... Immunosuppressi... | Modern acupunct... | 20 Years - 75 Years | Taipei Medical University WanFang Hospital | |
| Adult-to-Adult Living Donor Transplant Cohort Study | NCT01619475 | Liver Diseases Hepatocellular ... End Stage Liver... Hepatitis C Liver Cirrhosis | 18 Years - | Arbor Research Collaborative for Health | ||
| Characterization of Methylation Patterns in Hepatocellular Carcinoma | NCT04264754 | Hepatocellular ... Hepatocellular ... Cirrhosis | Blood collectio... | 22 Years - | Nucleix Ltd. | |
| Atezolizumab Plus Bevacizumab Alone or Combined With External Beam Radiotherapy for HCC With Macrovascular Invasion | NCT05992220 | Hepatocellular ... Hepatocellular ... Hepatocellular ... Hepatocellular ... Liver Cancer | Atezolizumab pl... Atezolizumab pl... | 20 Years - 79 Years | Asan Medical Center | |
| Volatile Organic Compounds for the Assessment of Liver Disease | NCT04620538 | Cirrhosis Cirrhosis, Live... Fibrosis, Liver Hepatocellular ... Hepatocellular ... | Breath Analysis | 18 Years - 90 Years | Imperial College London | |
| Clinical Application of Image-Guided Liver Surgery | NCT00878215 | Hepatocellular ... | Explorer Liver ... Explorer Liver ... Liver surgery Liver abalation | 18 Years - | Washington University School of Medicine | |
| A Study of Oxaliplatin and Capecitabine in Unresectable Metastatic Hepatocellular Cancer | NCT03026803 | Liver Cancer Hepatocellular ... | Oxaliplatin Capecitabine | 18 Years - | City of Hope Medical Center | |
| A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy | NCT06362369 | Advanced Cancer Advanced Solid ... Melanoma Metastasis Pleural Mesothe... Renal Cell Carc... MSI-High Mismatch Repair... Colorectal Canc... Hepatocellular ... Hepatocellular ... Renal Cell Canc... Kidney Cancer Skin Cancer Non Small Cell ... NSCLC Anaplastic Lymp... ALK Genomic Tum... | Alintegimod Ipilimumab Nivolumab | 18 Years - | 7 Hills Pharma, LLC | |
| A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation | NCT02073435 | Liver Diseases Hepatocellular ... Endstage Liver ... Liver Cirrhosis | Donor pain mana... | 21 Years - 60 Years | Northwestern University | |
| HCC Patient Preferences in Japan | NCT02616692 | Hepatocellular ... | Hepatocellular ... | 20 Years - | Bayer | |
| Sorafenib Concurrent With Yttrium-90 Transarterial Radioembolization in Patients With Advanced Hepatocellular Cancer | NCT02288507 | Hepatocellular ... | Sorafenib yttrium-90 radi... | 18 Years - | University of Hawaii | |
| Sorafenib Plus Toripalimab for Unresectable HCC With Portal Vein Tumor Thrombus | NCT04069949 | Unresectable He... Portal Vein Tum... | sorafenib; tori... | 18 Years - 74 Years | Sichuan University | |
| Natural History Study of Children and Adults With Fibrolamellar Hepatocellular Carcinoma | NCT03748927 | Hepatocellular ... Hepatocellular ... | 1 Year - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers | NCT03195699 | Breast Cancer Head and Neck S... Non Small Cell ... Hepatocellular ... Colorectal Canc... Gastric Adenoca... Melanoma Advanced Cancer | TTI-101 TTI-101 | 18 Years - 65 Years | Tvardi Therapeutics, Incorporated | |
| Sharing Decision-making Program for HCC Patients Treatment Decisions | NCT03926039 | Hepatocellular ... | sharing decisio... | 20 Years - | National Taipei University of Nursing and Health Sciences | |
| A Randomized Phase II Trial of Surgery Plus Sorafenib vs. Sorafenib Alone for Hepatocellular Cancer (HCC) With Portal Vein Invasion | NCT03971201 | Hepatocellular ... | hepatic resecti... Sorafenib | 18 Years - | White Plains Hospital | |
| A Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced Cancer | NCT02082210 | Advanced Cancer Gastric Adenoca... Gastroesophagea... Hepatocellular ... Renal Cell Carc... Non-Small Cell ... | Emibetuzumab Ramucirumab | 18 Years - | Eli Lilly and Company | |
| Clinical Recruitment of Patients With First-line Targeted Drug Resistance or Intolerance to Hepatocellular Cancer With PD-1 Inhibitor (Toripalimab,JS001) Detected on the NGS Platform Combined With Anlotinib | NCT05453383 | Hepatocellular ... | Anlotinib;Torip... | 18 Years - 75 Years | Eastern Hepatobiliary Surgery Hospital | |
| PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) | NCT04484636 | Hepatocellular ... Cholangiocarcin... Gallbladder Can... Pancreatic Canc... Oesophageal Can... Stomach Cancer | FoundationOne®C... | 18 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | |
| DC Bead LUMI (TM) Loaded With Doxorubicin for Intermediate Hepatocellular Carcinoma (HCC) | NCT03474354 | Hepatocellular ... Chemoembolizati... | chemoembolizati... | 18 Years - 88 Years | University of Athens | |
| Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor Q702 in Combination With Pembrolizumab in Patients With Selected Advanced Solid Tumors | NCT05438420 | Esophageal Canc... Gastric Cancer Hepatocellular ... Cervical Cancer | Q702 Pembrolizumab | 18 Years - | Qurient Co., Ltd. | |
| Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers | NCT02838836 | Non-small Cell ... Esophageal Canc... Gastric Cancer Pancreatic Canc... Hepatocellular ... Colorectal Canc... | Study sample co... | 18 Years - | University of Missouri-Columbia | |
| Radiofrequency Ablation Combined With Toripalimab and Lenvatinib in the Treatment of Short-term Recurrent Hepatocellular Carcinoma. | NCT05162898 | Recurrent Hepat... | toripalimab Lenvatinib Radiofrequency ... | 18 Years - 75 Years | Henan Cancer Hospital | |
| Radiofrequency Ablation Combined With Toripalimab and Lenvatinib in the Treatment of Short-term Recurrent Hepatocellular Carcinoma. | NCT05162898 | Recurrent Hepat... | toripalimab Lenvatinib Radiofrequency ... | 18 Years - 75 Years | Henan Cancer Hospital |
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