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Brief Title: Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer
Official Title: Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer
Study ID: NCT00185744
Brief Summary: To determine whether an accelerated course of radiotherapy delivered to the lumpectomy cavity plus margin using IORT as a single dose, intracavitary brachytherapy with the MammoSite device over 5 days, partial breast 3-D CRT in 5 days, or stereotactic APBI over 4 days is a feasible and safe alternative to a six and a half week course of whole breast radiotherapy. The study will measure both short and long-term complications of radiation treatment, short and long-term breast cosmesis, local rates of in-breast cancer recurrence, regional recurrences, distant metastases, and overall survival.
Detailed Description:
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Stanford University School of Medicine, Stanford, California, United States
Name: Frederick M. Dirbas
Affiliation: Stanford University
Role: PRINCIPAL_INVESTIGATOR