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lumpectomy with accelerated partial breast irradiation

single dose in the operating room after lumpectomy

Intra-Operative Radiotherapy (IORT)

Lumpectomy

Whole Breast Radiotherapy

Intracavitary Brachytherapy

Accelerated External Beam 3-D Conformal Radiotherapy

Stereotactic APBI

Frederick M. Dirbas

To determine whether an accelerated course of radiotherapy delivered to the lumpectomy cavity plus margin using IORT as a single dose, intracavitary brachytherapy with the MammoSite device over 5 days, partial breast 3-D CRT in 5 days, or stereotactic APBI over 4 days is a feasible and safe alternative to a six and a half week course of whole breast radiotherapy. The study will measure both short and long-term complications of radiation treatment, short and long-term breast cosmesis, local rates of in-breast cancer recurrence, regional recurrences, distant metastases, and overall survival.

Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer

Proportion of subjects that experience in-breast tumor recurrence (IBTR), to be assessed through or by March 2029

Stanford University

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer	NCT00185744	Breast Cancer Carcinoma, Duct...	Intra-Operative... Lumpectomy Whole Breast Ra... Intracavitary B... Accelerated Ext... Stereotactic AP...	40 Years -	Stanford University
Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer	NCT00185744	Breast Cancer Carcinoma, Duct...	Intra-Operative... Lumpectomy Whole Breast Ra... Intracavitary B... Accelerated Ext... Stereotactic AP...	40 Years -	Stanford University

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