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Spots Global Cancer Trial Database for Neoadjuvant Chemotherapy Including Sorafenib in Women With Previously Untreated Primary Breast Cancer

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Neoadjuvant Chemotherapy Including Sorafenib in Women With Previously Untreated Primary Breast Cancer

Official Title: Phase II Study of Neoadjuvant Epirubicin, Cyclophosphamide (EC) + Sorafenib Followed by Paclitaxel (P) + Sorafenib in Women With Previously Untreated

Study ID: NCT00548899

Conditions

Breast Cancer

Interventions

Nexavar (Sorafenib)

Study Description

Brief Summary: The purpose of this study is to determine the efficacy and safety of sorafenib in the neoadjuvant setting in patients with primary breast cancer

Detailed Description: Epirubicin/Cyclophosphamide followed by Paclitaxel (EC/P) is a well tolerated regimen with high clinical activity. Histopathological complete remission after preoperative chemotherapy has a direct correlation with the disease-free and overall survival. The aim of combining a chemotherapy regime with sorafenib in the neoadjuvant setting is to increase the locoregional and systemic outcome of these patients

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

St. Gertrauden Krankenhaus, Berlin, , Germany

Klinikum der J. W. Goethe Universität, Frankfurt am Main, , Germany

Henriettenstiftung, Hannover, , Germany

Elisabeth Krankenhaus, Kassel, , Germany

Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel, , Germany

Klinikum der Universität zu Köln, Köln, , Germany

Klinikum Offenbach, Offenbach, , Germany

Klinikum Südstadt, Rostock, , Germany

Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, , Germany

Contact Details

Name: Sibylle Loibl, MD

Affiliation: GBG Forschungs GmbH

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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