Spots Global Cancer Trial Database for neoadjuvant chemotherapy
Every month we try and update this database with for neoadjuvant chemotherapy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Induction Chemotherapy for Locally Advanced Rectal Cancer | NCT04838496 | Rectal Cancer | FOLFOXIRI Proto... | 18 Years - | Catharina Ziekenhuis Eindhoven | |
| Sentinel Lymph Node Biopsy in Clinically Node-negative Early Breast Cancer Patients After Neoadjuvant Chemotherapy | NCT03381092 | Invasive Breast... | - 70 Years | Peking University | ||
| Tc99m Sestamibi Molecular Breast Imaging | NCT02324387 | Breast Cancer | Molecular Breas... Tc99m sestamibi | 18 Years - | M.D. Anderson Cancer Center | |
| Preoperative Boost Associated With Neoadjuvant Chemotherapy in Luminal B Breast Cancer | NCT05673304 | Breast Cancer Radiotherapy | SBRT anticipate... | 18 Years - | IRCCS Azienda Ospedaliero-Universitaria di Bologna | |
| Neoadjuvant Chemotherapy Versus Surgery Alone in Patients With High-Grade UTUC | NCT02876861 | High-Grade Uppe... | Radical nephrou... Distal ureterec... Neoadjuvant Che... | 18 Years - 80 Years | Xiangya Hospital of Central South University | |
| PD-1 Blockade With JS001 Plus Neoadjuvant Chemotherapy for Gastric/Gastroesophageal Junction Cancer | NCT05033392 | Stomach Neoplas... | Toripalimab Inj... | 18 Years - 79 Years | Shenzhen People's Hospital | |
| Avoiding Sentinel Lymph Node Biopsy in Breast Cancer Patients After Neoadjuvant Chemotherapy | NCT04225858 | Breast Cancer Triple Negative... HER2-positive B... Sentinel Lymph ... | Omission of sen... | 18 Years - | The Netherlands Cancer Institute | |
| Molecular Triaging of Newly Diagnosed Breast Cancer | NCT01159236 | Breast Cancer | Paclitaxel Fluorouracil Doxorubicin Epirubicin Cyclophosphamid... Bevacizumab | 18 Years - | M.D. Anderson Cancer Center | |
| The Efficacy and Safety of Abraxane Combined With Epirubicin as Neoadjuvant Chemotherapy in Breast Cancer | NCT03647280 | Breast Cancer | Abraxane Epirubicin | 18 Years - 60 Years | Zhejiang Cancer Hospital | |
| Targeted Next Generation Sequencing for the Efficacy of Trastuzumab Neoadjuvant Chemotherapy in Breast Cancer | NCT03728829 | Observational Prospective | Trastuzumab+TP | 18 Years - 70 Years | Hebei Medical University Fourth Hospital | |
| Intraoperative Radiation Therapy for Resectable Pancreatic Cancer | NCT05181488 | Resectable Panc... | intraoperative ... | 20 Years - | Gangnam Severance Hospital | |
| Basal Tumours in Bladder Cancer, Response to chemoTherapy | NCT04089748 | Bladder Cancer Chemotherapy Ef... | neoadjuvant che... | 18 Years - 80 Years | University Hospital, Rouen | |
| Trial of Neoadjuvant Chemotherapy With S1 Plus Paclitaxel-albumin on Pancreatic Cancer | NCT03585062 | Pancreatic Canc... Neoadjuvant Che... | S1, Paclitaxel-albu... | 18 Years - 80 Years | Zhejiang Provincial People's Hospital | |
| Reduction Of Cycles of neOadjuvant Chemotherapy for Advanced Epithelial Ovarian, Fallopian and Primary Peritoneal Cancer | NCT03693248 | Ovarian Cancer ... Ovarian Cancer ... Fallopian Tube ... Peritoneal Canc... | Two cycles of n... | 20 Years - 80 Years | Seoul National University Hospital | |
| Neoadjuvant Modified FOLFIRINOX in Borderline Resectable Pancreatic Cancer | NCT02749136 | Pancreatic Aden... | Preoperative mo... | 19 Years - | Asan Medical Center | |
| Improving Response to Chemotherapy by Adding Physical Exercise in the Neoadjuvant Setting of Breast Cancer Patients | NCT05976815 | Breast Cancer | Combined Aerobi... | 18 Years - | University Institute of Maia | |
| Vabb After Neoadjuvant Therapy to Avoid Surgery-pCR to Avoid Breast Surgery | NCT06281210 | Breast Cancer Triple Negative... HER2-positive B... Neoadjuvant Che... | Omission of sur... | 18 Years - | European Institute of Oncology | |
| Treatment Outcomes of Hepatic Metastasis After FOLFOX-4 Therapy | NCT00610636 | Colorectal Canc... | Hepatic resecti... | 18 Years - 80 Years | National Taiwan University Hospital | |
| Phase II Study With Catumaxomab in Patients With Gastric Cancer After Neoadjuvant CTx and Curative Resection | NCT00464893 | Gastric Cancer Gastric Adenoca... | Catumaxomab catumaxomab | 18 Years - | Neovii Biotech | |
| Feasibility Study of Neoadjuvant Chemotherapy Modified FOLFOX6 for Resectable Liver Metastases of Colorectal Cancers | NCT00594529 | Colorectal Canc... Liver Metastasi... | Surgery | 20 Years - 80 Years | Kyoto University Hospital | |
| Neoadjuvant Chemotherapy for Patients With Advanced Gastric Cancer in ERAS Programs for Radical Gastrectomy | NCT03238404 | Gastric Cancer | NAC group Surgery alone g... | 18 Years - 75 Years | Jinling Hospital, China | |
| Perioperative Chemotherapy Combined With HIPEC for High-risk Advanced Gastric Cancer | NCT02960061 | Survival | Neoadjuvant che... D2 radical rese... Hyperthermic in... Adjuvant chemot... | 18 Years - 75 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
| Efficacy Study of Neoadjuvant Chemotherapy to Treat Advanced Ovarian Cancer | NCT01462149 | Advanced Ovaria... | Neoadjuvant che... Carboplatin | 20 Years - 80 Years | Asan Medical Center | |
| Study of Oxaliplatin, Calcium Folinate, and 5-Fluorouracil as Neoadjuvant Chemotherapy for Resectable Advanced Gastric Cancer | NCT00591045 | Stomach Neoplas... Gastric Cancer | mFOLFOX | 30 Years - 70 Years | Peking University | |
| Neoadjuvant Chemotherapy for Patients With Advanced Gastric Cancer in ERAS Programs for Radical Gastrectomy | NCT03238404 | Gastric Cancer | NAC group Surgery alone g... | 18 Years - 75 Years | Jinling Hospital, China | |
| Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma (NPC) | NCT00817583 | Nasopharyngeal ... | docetaxel, cisp... 3D-CRT (three-d... | 18 Years - 70 Years | Fudan University | |
| Feasibility in Identification of Breast Cancer Candidates for Elimination of Axillary Surgery | NCT05663021 | Breast Cancer | Ultrasound-guid... | 18 Years - 70 Years | Fudan University | |
| Research on Intelligent Screening and Decision-making for Neoadjuvant Therapy in Locally Advanced Gastric Cancer Based on Multi-omics Integration | NCT06396143 | Locally Advance... | 18 Years - 75 Years | Zhejiang University | ||
| Organoids Based Drug Sensitivity in Neoadjuvant Chemotherapy of Breast Cancer | NCT06155305 | Organoids Breast Cancer Neoadjuvant Che... | Biopsy | 18 Years - 70 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University | |
| The Clinical Research of Neoadjuvant Chemotherapy Combined Surgery for Locally Advanced Cervical Cancer | NCT02471027 | Cervical Cancer | Neoadjuvant che... | 18 Years - | Capital Medical University | |
| Sentinel Lymph Node Biopsy in Clinically Node-negative Early Breast Cancer Patients After Neoadjuvant Chemotherapy | NCT03381092 | Invasive Breast... | - 70 Years | Peking University | ||
| Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer | NCT03150576 | Breast Cancer | Olaparib Paclitaxel and ... | 16 Years - 70 Years | Cambridge University Hospitals NHS Foundation Trust | |
| Stress-reducing Intervention in Urothelial Carcinoma | NCT06269536 | Bladder Cancer | HRV biofeedback | 18 Years - | Comenius University | |
| Imaging for Response Assessment of Neoadjuvant Chemotherapy in Primary Breast Cancer (GALADON) | NCT01690325 | Breast Cancer | Docetaxel Trastuzumab Bevacizumab Epirubicin Cyclophosphamid | 18 Years - 65 Years | West German Study Group | |
| Neoadjuvant Chemotherapy Versus Surgery Alone in Patients With High-Grade UTUC | NCT02876861 | High-Grade Uppe... | Radical nephrou... Distal ureterec... Neoadjuvant Che... | 18 Years - 80 Years | Xiangya Hospital of Central South University | |
| Ifosfamide, Doxorubicin and Hypofractionated Radiotherapy in Neoadjuvant Sarcoma Treatment | NCT02812654 | Sarcoma, Soft T... | Doxorubicin Ifosfamide radiotherapy | 18 Years - 75 Years | AC Camargo Cancer Center | |
| Breast MRI for Neaodjuvant Chemotherapy Response Prediction and Evaluation in Breast Cancer | NCT03580837 | Breast Cancer | 18 Years - | University Hospital, Strasbourg, France | ||
| Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer | NCT06386887 | Epithelial Ovar... | Intermittent Fa... Neoadjuvant che... | 18 Years - | Case Comprehensive Cancer Center | |
| Observation and Evaluation of Short-term Curative Effect of Local Advanced Cervical Cancer Treated With Particle Radiotherapy Versus Neoadjuvant Chemotherapy | NCT03225443 | Uterine Cervica... Locally Advance... | - | Shanghai First Maternity and Infant Hospital | ||
| Pembrolizumab Plus Neoadjuvant Chemotherapy for Locally Advanced EGJ Adenocarcinoma | NCT04813523 | Adenocarcinoma ... Neoadjuvant Che... Pembrolizumab | Pembrolizumab I... | 18 Years - 75 Years | Tianjin Medical University Cancer Institute and Hospital | |
| Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer | NCT06039631 | Larynx Cancer Hypopharyngeal ... | Surgery Radiation Toripalimab | 18 Years - 75 Years | Fudan University | |
| Aromatherapy in the Treatment of Early Breast Cancer | NCT06435104 | Early Breast Ca... | neoadjuvant che... aromatherapy | 18 Years - 80 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Trial of Neoadjuvant Endostar, Docetaxel and Epirubicin for Patients With Breast Cancer | NCT01479036 | Breast Cancer | docetaxel and e... docetaxel and e... | 18 Years - 70 Years | Xijing Hospital | |
| Trial of Chemotherapy in Ovarian, Fallopian Tube and Peritoneal Carcinoma | NCT01519869 | Primary Periton... Ovarian Carcino... Fallopian Tube ... | neoadjuvant che... | 18 Years - | University of Kentucky | |
| Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy | NCT04109079 | Breast Cancer Sentinel Lymph ... Neoplasm, Breas... | Axillary lymph ... Axillary radiot... Breast or chest... | 18 Years - | University Hospitals of Derby and Burton NHS Foundation Trust | |
| Pathological Complete Response Rate in Locally Advanced Breast Cancer With FEC, EC-T, or TC as Neoadjuvant Chemotherapy | NCT03349177 | Breast Cancer Pathological Co... Neoadjuvant Che... | Epirubicin Fluorouracil Docetaxel Cyclophosphamid... | 18 Years - 70 Years | Shandong Cancer Hospital and Institute | |
| MRI Radiomics Assessing Neoadjuvant Chemotherapy in Breast Cancer to Predict Lymph Node Metastasis and Prognosis(RBC-02) | NCT04004559 | Invasive Breast... Neoadjuvant Che... Radiomics Axillary Lymph ... Prognosis | No intervention... | 18 Years - 75 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Paclitaxel, Carboplatin and Gemcitabine in the Treatment of Patients With Advanced Transitional Cell Cancer of the Bladder | NCT00136175 | Bladder Cancer | Paclitaxel Carboplatin Gemcitabine | 18 Years - | University of Michigan Rogel Cancer Center | |
| Systematic Lymphadenectomy During Interval Debulking Surgery in Advanced Epithelial Ovarian Cancer | NCT06385912 | Ovarian Cancer Postoperative C... Neoadjuvant The... Lymph Node Exci... | lymphadenectomy | - | Tongji Hospital | |
| Paclitaxel i.v. Plus Cisplatin i.p for NACT in Patients With Advanced Ovarian Cancer | NCT04885270 | Epithelial Carc... Neoadjuvant Che... | cisplatin i.p. | 18 Years - 75 Years | West China Second University Hospital | |
| Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer | NCT03358017 | Triple Negative... | Zoledronate Atorvastatin 80... Standard neoadj... | 18 Years - | Mario Negri Institute for Pharmacological Research | |
| Sentinel Lymph Node Detection After Neoadjuvant Chemotherapy for Large Operable Breast Cancer | NCT01221688 | Breast Cancer | Axillar Sentine... SLNB and comple... | 18 Years - | Institut Cancerologie de l'Ouest | |
| Impact of Preoperative Chemotherapy on Complications and Regeneration After Resection of Colorectal Liver Metastases | NCT00779272 | Colorectal Live... | - | University of Zurich | ||
| Fasting Mimicking Diet Program to ImpRovE ChemoTherapy in Hormone Receptor Postive (HR+), HER2- Breast Cancer | NCT05503108 | Fasting Mimicki... HER2-negative B... Hormone Recepto... Pathological Co... Objective Respo... Neoadjuvant Che... | Fasting Mimicki... | 18 Years - | Leiden University Medical Center | |
| Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients | NCT06225284 | Triple Negative... Premenopausal B... | Goserelin Aceta... | 18 Years - 50 Years | National Taiwan University Hospital | |
| A Multicenter Trial Evaluating the Efficacy of Nedaplatin in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma | NCT01479504 | Nasopharyngeal ... | nedaplatin and ... cisplatin and d... nedaplatin and ... cisplatin and d... | 18 Years - 70 Years | Guangxi Medical University | |
| Clinical Effect of Neoadjuvant Hierarchical Treatment Based on Chemotherapy | NCT03071198 | Rectum Cancer | TME Concurrent chem... neoadjuvant CT adjuvant CT | 20 Years - 70 Years | Harbin Medical University | |
| Perioperative Chemotherapy Combined With HIPEC for High-risk Advanced Gastric Cancer | NCT02960061 | Survival | Neoadjuvant che... D2 radical rese... Hyperthermic in... Adjuvant chemot... | 18 Years - 75 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
| Comparative Study of Different Neoadjuvant Therapies Before Radical Hysterectomy in Stage Ib2-IIa2 Cervical Cancer | NCT03243825 | Cervical Cancer | combination gro... chemotherapy gr... | 25 Years - 70 Years | ChineseAMS | |
| Borderline Resectable Pancreatic Cancer Neoadjuvant Chemoradiotherapy Clinicaltrial-1 | NCT03777462 | Pancreatic Canc... | Neoadjuvant gem... Neoadjuvant gem... Neoadjuvant S-1... | 18 Years - 80 Years | Changhai Hospital | |
| Neoadjuvant Chemotherapy With Nab-paclitaxel Plus Cisplatin for Stage Ⅱ-Ⅲ Esophageal Cancer Patients | NCT01258192 | Esophageal Squa... | albumin-bound p... | 18 Years - 70 Years | Zhejiang Cancer Hospital | |
| Cetuximab in Combination With Anti-PD-1 and mFOLFOX Treat For RAS/BRAF wt Right-Sided Colon Cancer | NCT05468177 | Colonic Neoplas... | neoadjuvant che... | 18 Years - 70 Years | Tongji Hospital | |
| Phase II Study of Neoadjuvant XELOX + Lapatinib in HER2(+) Gastric Cancer Patients With Liver Metastasis | NCT02015169 | HER2-positive G... | Lapatinib | 18 Years - | Samsung Medical Center | |
| Induction Chemotherapy Followed by Standard Therapy in Cervical Cancer With Aortic Lymph Node Spread | NCT03534713 | Cervical Cancer... | Carboplatin Paclitaxel Cisplatin Radiotherapy | 18 Years - | University Hospital, Toulouse | |
| Aromatherapy in the Treatment of Early Breast Cancer | NCT06435104 | Early Breast Ca... | neoadjuvant che... aromatherapy | 18 Years - 80 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Apatinib Plus XELOX as Neoadjuvant Therapy in Locally Advanced Gastric Cancer | NCT03229096 | Chemotherapy Ef... Chemotherapeuti... Gastric Cancer | Apatinib plus X... | 18 Years - 75 Years | Shanghai Zhongshan Hospital | |
| Neoadjuvant Chemoradiotherapy vs. Chemotherapy With Radical Gastrectomy and Adjuvant Chemotherapy for Advanced Gastric Cancer | NCT01815853 | Gastric Cancer | Neoadjuvant Che... Neoadjuvant Che... R0 D2 Gastrecto... Adjuvant Chemot... | 18 Years - 75 Years | Sun Yat-sen University | |
| NEOZOL_Follow-up Study | NCT04899713 | Locally Advance... | Survival survey | 18 Years - | Hospices Civils de Lyon | |
| Phase Ⅱ Study of Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for Stage Ⅲ Nasopharyngeal Carcinoma | NCT00816855 | Nasopharyngeal ... | docetaxel, cisp... | 18 Years - 70 Years | Fudan University | |
| Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer | NCT01918527 | Colon Cancer | Capecitabine Oxaliplatin | 18 Years - | Vejle Hospital | |
| S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer | NCT02177695 | Bladder Cancer | Gemcitabine Cisplatin Methotrexate Vinblastine Doxorubicin Filgrastim | 18 Years - | SWOG Cancer Research Network | |
| What Factors Affect Breast Cancer Neoadjuvant Chemotherapy Efficacy? | NCT03501394 | Breast Neoplasm... | Magnetic Resona... Histopathologic... Health Question... | 18 Years - | University of Aberdeen | |
| Neo-Sequence 1: Neoadjuvant Chemotherapy With or Without Antiangiogenesis and Sequential Immunotherapy for HER2-negative MMR-proficient Locally Advanced Gastric or Gastroesophageal Adenocarcinoma | NCT05540145 | Gastric Cancer | SOX plus Paclit... | 18 Years - 75 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| Docetaxel, Carboplatin, and Capecitabine as Treatment for Patients With Locally Advanced or Inflammatory Breast Cancer Before Surgery | NCT00251329 | Breast Cancer | neoadjuvant che... | 18 Years - | Cancer Research Network | |
| Neoadjuvant Chemotherapy + Herceptin in HER2 Positive Stage II-III Breast Cancer Patients | NCT00270894 | Breast Neoplasm | epirubicin cyclophosphamid... docetaxel trastuzumab | 18 Years - | Accelerated Community Oncology Research Network | |
| Treatment Outcomes of Hepatic Metastasis After FOLFOX-4 Therapy | NCT00610636 | Colorectal Canc... | Hepatic resecti... | 18 Years - 80 Years | National Taiwan University Hospital | |
| Neoadjuvant Chemotherapy With SEEOX Regimen for Borrmann Type 4 Gastric Cancer | NCT02949258 | Stomach Neoplas... Gastric Cancer | oxaliplatin etoposide epirubicin S1 | 30 Years - 75 Years | Jinling Hospital, China | |
| Comparison Between NCRT and NCT Followed by MIE for Treatment of Locally Advanced Resectable ESCC | NCT03001596 | Esophageal Squa... | Neoadjuvant Che... Neoadjuvant Che... Minimally Invas... | 18 Years - 75 Years | Shanghai Zhongshan Hospital | |
| Registry Trial to Evaluate the Clinical Utilization of Targeted Axillary Dissection (TAD) | NCT03102307 | Early Stage Bre... | Not suitable fo... Suitable for TA... | 18 Years - | Kliniken Essen-Mitte | |
| Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC | NCT03562637 | Triple Negative... | adagloxad simol... Globo H IHC Ass... Standard of car... | 18 Years - | OBI Pharma, Inc |
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