Spots Global Cancer Trial Database for Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
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Trial Identification
Brief Title: Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
Official Title: Gene Expression Signature and Immunohistochemical Markers Associated With Response to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
Study ID: NCT00820690
Conditions
Study Description
Brief Summary: The purpose of this study is to analyze gene expression signature and immunohistochemical markers associated with clinical and pathological response to neoadjuvant chemotherapy in locally advanced breast cancer.
Detailed Description: Locally advanced breast cancer is a common condition in development countries. Neoadjuvant chemotherapy gives the opportunity to identify genetic signatures associated with objective clinical and pathological complete responses. Patients will receive doxorubicin/cyclophosphamide with paclitaxel. Tumor samples collected before and after chemotherapy will be analyzed.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Barretos Cancer Hospital, Barretos, São Paulo, Brazil
Contact Details
Name: Maria Aparecida A Koike Folgueira, MD, PhD
Affiliation: Faculdade de Medicina - Universidade de São Paulo
Role: STUDY_CHAIR
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