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Brief Title: Deep Learning Algorithms for Prediction of Lymph Node Metastasis and Prognosis in Breast Cancer MRI Radiomics (RBC-01)
Official Title: Deep Learning Algorithms for Prediction of Lymph Node Metastasis and Prognosis in Breast Cancer MRI Radiomics (RBC-01)
Study ID: NCT04003558
Brief Summary: This bi-directional, multicentre study aims to assess multiparametric MRI Radiomics-based prediction model for identifying metastasis lymph nodes and prognostic prediction in breast cancer.
Detailed Description: Sensitivity for prediction of lymph node metastasis and survival of currently available prognostic scores in limited. This study proposes to establish a deep learning algorithms of multiparametric MRI radiomics and nomogram for identifying lymph node metastasis and prognostic prediction of breast cancer. The study will investigate the relationship between the radiomics and the tumor microenvironment. The study includes the construction of multiparametric MRI radiomics-based prediction model and the validation of the prediction model.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Tungwah Hospital of Sun Yat-Sen University, Dongguan, Guangdong, China
Shunde hospital of southern medical university, Foshan, Guangdong, China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, Guangdong, China
Sun Yat-Sen Memorial Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Name: Herui Yao, PhD
Affiliation: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Role: STUDY_CHAIR
Name: Chuanmiao Xie, PhD
Affiliation: Sun Yat-sen University
Role: PRINCIPAL_INVESTIGATOR
Name: Jie Ouyang, PhD
Affiliation: Tungwah Hospital of Sun Yat-Sen University
Role: PRINCIPAL_INVESTIGATOR
Name: Qiugen Hu, PhD
Affiliation: Southern Medical University, China
Role: PRINCIPAL_INVESTIGATOR
Name: Haotian Lin, PhD
Affiliation: Zhongshan Ophthalmic Center, Sun Yat-sen University
Role: PRINCIPAL_INVESTIGATOR