Spots Global Cancer Trial Database for early stage breast cancer
Every month we try and update this database with for early stage breast cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Anti-proliferative Effects of Vitamin D and Melatonin in Breast Cancer | NCT01965522 | Early Stage Bre... | Melatonin Vitamin D Placebo (melato... Placebo (vitami... | 18 Years - | Juravinski Cancer Center | |
| Accelerated Partial Breast Radiotherapy With Either Mammosite or Intensity Modulated Radiotherapy | NCT01185145 | Breast Cancer | Breast Brachyth... Intensity Modul... | 40 Years - | Rocky Mountain Cancer Centers | |
| Cyberknife for Early Stage Breast Cancer | NCT03946683 | Early Stage Bre... | Cyberknife for ... | 45 Years - 45 Years | NYU Langone Health | |
| Intensity Modulated Accelerated Partial Breast Irradiation Before Surgery in Treating Older Patients With Hormone Responsive Stage 0-I Breast Cancer | NCT02186470 | Estrogen Recept... Invasive Ductal... Invasive Ductal... Medullary Ducta... Mucinous Ductal... Papillary Ducta... Progesterone Re... Stage IA Breast... Stage IB Breast... Tubular Ductal ... | accelerated par... intensity-modul... image-guided ra... therapeutic con... | 50 Years - | Ohio State University Comprehensive Cancer Center | |
| Pharmacokinetics of SPI-2012 (Eflapegrastim) in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide (TC) Chemotherapy | NCT03135951 | Breast Cancer Pharmacokinetic... | SPI-2012 | 18 Years - | Spectrum Pharmaceuticals, Inc | |
| Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer | NCT04187898 | Neutropenia Breast Cancer | Eflapegrastim Eflapegrastim Eflapegrastim Eflapegrastim Docetaxel Cyclophosphamid... | 18 Years - 55 Years | Spectrum Pharmaceuticals, Inc | |
| Study of Dose-dense Adriamycin Plus Cytoxan (AC) Followed by Either ABI-007 (Abraxane) or Taxol With Bevacizumab as Adjuvant Therapy for Patients With Breast Cancer | NCT00394251 | Breast Cancer | Adriamycin and ... ABI-007 Taxol Bevacizumab pegfilgrastim | 18 Years - 70 Years | Celgene | |
| Efficacy and Safety of HILOTERM® Device for the Prevention of Peripheral Neuropathy | NCT06422949 | Breast Cancer Neuropathy;Peri... | Hilotherm® Cool... | 18 Years - | European Institute of Oncology | |
| Enhancing Shared Decision-Making in Metastatic Breast Cancer (Qualitative Study) | NCT03248258 | Decision Making... De-escalation | Qualitative Int... | 18 Years - | University of Alabama at Birmingham | |
| Neoadjuvant Therapy With Herceptin and Taxol for Breast Cancer | NCT00136539 | Breast Cancer | Herceptin Taxol Adriamycin Cytoxan | 18 Years - | Dana-Farber Cancer Institute | |
| Cyberknife for Early Stage Breast Cancer | NCT03946683 | Early Stage Bre... | Cyberknife for ... | 45 Years - 45 Years | NYU Langone Health | |
| Registry Trial to Evaluate the Clinical Utilization of Targeted Axillary Dissection (TAD) | NCT03102307 | Early Stage Bre... | Not suitable fo... Suitable for TA... | 18 Years - | Kliniken Essen-Mitte | |
| Administration During Chemotherapy to Reduce Ovarian Failure Following Chemotherapy in Early Stage, Hormone-Receptor Negative Breast Cancer | NCT01530607 | Breast Cancer | Standard cyclop... Goserelin (Zola... | 18 Years - 50 Years | King Faisal Specialist Hospital & Research Center | |
| Study of CoQ10 During One Cycle of Doxorubicin Treatment for Breast Cancer | NCT00976131 | Breast Cancer | CoQ10 CoQ10 Placebo Doxorubicin Cyclophosphamid... | 21 Years - | Columbia University | |
| Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients | NCT00309569 | Early Stage Bre... | Cyclophosphamid... Methotrexate Fluorouracil Epirubicin Surgery | 18 Years - 80 Years | Austrian Breast & Colorectal Cancer Study Group | |
| Cyberknife® Partial Breast Irradiation (PBI) for Early Stage Breast Cancer | NCT01162200 | Early Stage Bre... | Stereotactic Bo... | 18 Years - 99 Years | University of Texas Southwestern Medical Center | |
| Anti-proliferative Effects of Vitamin D and Melatonin in Breast Cancer | NCT01965522 | Early Stage Bre... | Melatonin Vitamin D Placebo (melato... Placebo (vitami... | 18 Years - | Juravinski Cancer Center | |
| Anti-proliferative Effects of Vitamin D and Melatonin in Breast Cancer | NCT01965522 | Early Stage Bre... | Melatonin Vitamin D Placebo (melato... Placebo (vitami... | 18 Years - | Juravinski Cancer Center | |
| A Randomized, Controlled Trial to Determine the Effects of an Exercise Intervention on Physical Activity During Chemotherapy for Patients With Early Stage Breast Cancer | NCT02159157 | Early Stage Bre... | Exercise prescr... | 18 Years - 99 Years | Dartmouth-Hitchcock Medical Center | |
| Efficacy and Safety of HILOTERM® Device for the Prevention of Peripheral Neuropathy | NCT06422949 | Breast Cancer Neuropathy;Peri... | Hilotherm® Cool... | 18 Years - | European Institute of Oncology | |
| Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer | NCT04458532 | Early Stage Bre... | Aerobic Trainin... Aerobic Trainin... Aerobic Trainin... Aerobic Trainin... | 21 Years - 80 Years | Memorial Sloan Kettering Cancer Center | |
| Partial Breast Irradiation Using Interstitial Permanent Palladium-103 Seed Implant | NCT02297672 | Early Stage Bre... | Stranded pallad... 3 dimensional b... Computerized to... | 55 Years - 80 Years | British Columbia Cancer Agency | |
| Neoadjuvant Therapy With Herceptin and Taxol for Breast Cancer | NCT00136539 | Breast Cancer | Herceptin Taxol Adriamycin Cytoxan | 18 Years - | Dana-Farber Cancer Institute | |
| Assessment of the Decision-making Impact of the Breast Cancer Index in Recommending Extended Adjuvant Endocrine Therapy for Patients With Early Stage ER-positive Breast Cancer | NCT02057029 | Breast Cancer Early Stage Est... | BCI Assay Resul... | - | Yale University | |
| Impact of Breast Magnetic Resonance Imaging (MRI) on Mastectomy Rates | NCT01166581 | Early Stage Bre... | 18 Years - 85 Years | Summa Health System | ||
| Neoadjuvant Therapy With Herceptin and Taxol for Breast Cancer | NCT00136539 | Breast Cancer | Herceptin Taxol Adriamycin Cytoxan | 18 Years - | Dana-Farber Cancer Institute | |
| Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients | NCT00309569 | Early Stage Bre... | Cyclophosphamid... Methotrexate Fluorouracil Epirubicin Surgery | 18 Years - 80 Years | Austrian Breast & Colorectal Cancer Study Group | |
| Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients | NCT05350722 | Breast Cancer | Single dose abl... | 50 Years - | Amsterdam UMC, location VUmc | |
| Enhancing Shared Decision-Making in Metastatic Breast Cancer (Qualitative Study) | NCT03248258 | Decision Making... De-escalation | Qualitative Int... | 18 Years - | University of Alabama at Birmingham | |
| Granulocyte-colony Stimulating Factors or Antibiotics for Primary Prophylaxis for Febrile Neutropenia | NCT02816112 | Early Stage Bre... | Ciprofloxacin Neupogen | 19 Years - | Ottawa Hospital Research Institute | |
| Nanoparticle Albumin-Bound (Nab) Paclitaxel/Cyclophosphamide in Early-Stage Breast Cancer | NCT00629499 | Breast Cancer | nab paclitaxel Cyclophosphamid... Trastuzumab | 18 Years - | SCRI Development Innovations, LLC | |
| Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE) | NCT01077154 | Breast Cancer | Placebo Denosumab | 18 Years - | Amgen | |
| Impact of Breast Magnetic Resonance Imaging (MRI) on Mastectomy Rates | NCT01166581 | Early Stage Bre... | 18 Years - 85 Years | Summa Health System | ||
| SPI-2012 vs Pegfilgrastim in Management of Neutropenia in Breast Cancer Participants With Docetaxel and Cyclophosphamide | NCT02953340 | Neutropenia Breast Cancer | SPI-2012 Pegfilgrastim Docetaxel Cyclophosphamid... | 18 Years - | Spectrum Pharmaceuticals, Inc | |
| Assessment of the Decision-making Impact of the Breast Cancer Index in Recommending Extended Adjuvant Endocrine Therapy for Patients With Early Stage ER-positive Breast Cancer | NCT02057029 | Breast Cancer Early Stage Est... | BCI Assay Resul... | - | Yale University | |
| Targeted Intraoperative Therapy Registry at Bethesda North Hospital (TARGIT) | NCT02364960 | Early Stage Bre... Neoplasm of the... Breast Tumor | 45 Years - | TriHealth Inc. | ||
| A Pragmatic Trial of Ambulatory Toxicity Management in Patients Receiving Adjuvant or Neo-adjuvant Chemotherapy for Early Stage Breast Cancer | NCT02485678 | Early Stage Bre... | Proactive Telep... Control Arm PRO Sub-Study | 18 Years - | Ontario Clinical Oncology Group (OCOG) | |
| Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite (Amigo) In Breast-Conserving Therapy | NCT02335671 | Early Stage Bre... Breast Cancer S... Breast Cancer S... | Intra-operative... Mass Spectromet... | 18 Years - 75 Years | Dana-Farber Cancer Institute | |
| Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC) | NCT02950259 | Breast Neoplasm Breast Neoplasm... Triple Negative... | Cyclophosphamid... Indomethacin Omeprazole Multivitamin | - | Providence Health & Services | |
| Impact of Breast Magnetic Resonance Imaging (MRI) on Mastectomy Rates | NCT01166581 | Early Stage Bre... | 18 Years - 85 Years | Summa Health System | ||
| A Randomized, Controlled Trial to Determine the Effects of an Exercise Intervention on Physical Activity During Chemotherapy for Patients With Early Stage Breast Cancer | NCT02159157 | Early Stage Bre... | Exercise prescr... | 18 Years - 99 Years | Dartmouth-Hitchcock Medical Center | |
| Phase I Dose Escalation of Single Fraction Adjuvant Stereotactic Body Partial Breast Irradiation Early Stage Breast CA | NCT02685332 | Early Stage Bre... | Stereotactic Ra... | 18 Years - | University of Texas Southwestern Medical Center | |
| Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients | NCT05350722 | Breast Cancer | Single dose abl... | 50 Years - | Amsterdam UMC, location VUmc | |
| Impact of Breast Magnetic Resonance Imaging (MRI) on Mastectomy Rates | NCT01166581 | Early Stage Bre... | 18 Years - 85 Years | Summa Health System | ||
| Association of Adjuvant Radiotherapy of Non-metastatic Breast Carcinoma With Immunomodulation and Circulating Tumor Cell Phenotype in Relation to Patient Age. | NCT04902937 | Tumor Cell, Cir... | Adjuvant radiot... neoadjuvant and... | 18 Years - | University of Jena | |
| Pilot Study to Evaluate the Impact of Denosumab on Disseminated Tumor Cells (DTC) in Patients With Early Stage Breast Cancer | NCT01545648 | Early Stage Bre... | Denosumab | 18 Years - | University of California, San Francisco | |
| SPI-2012 vs Pegfilgrastim in the Management of Neutropenia in Participants With Breast Cancer With Docetaxel and Cyclophosphamide (ADVANCE) | NCT02643420 | Neutropenia Breast Cancer | SPI-2012 Pegfilgrastim Docetaxel Cyclophosphamid... | 18 Years - | Spectrum Pharmaceuticals, Inc | |
| Pilot Study to Evaluate the Impact of Denosumab on Disseminated Tumor Cells (DTC) in Patients With Early Stage Breast Cancer | NCT01545648 | Early Stage Bre... | Denosumab | 18 Years - | University of California, San Francisco | |
| Percent Weight Change in the Medical Supplement Group of Early Breast Cancer | NCT06311357 | Early Stage Bre... | Ensure | 18 Years - 80 Years | Rajavithi Hospital | |
| Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients | NCT05350722 | Breast Cancer | Single dose abl... | 50 Years - | Amsterdam UMC, location VUmc | |
| Partial Breast Irradiation Using Interstitial Permanent Palladium-103 Seed Implant | NCT02297672 | Early Stage Bre... | Stranded pallad... 3 dimensional b... Computerized to... | 55 Years - 80 Years | British Columbia Cancer Agency | |
| Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE) | NCT01077154 | Breast Cancer | Placebo Denosumab | 18 Years - | Amgen | |
| Intensity Modulated Accelerated Partial Breast Irradiation Before Surgery in Treating Older Patients With Hormone Responsive Stage 0-I Breast Cancer | NCT02186470 | Estrogen Recept... Invasive Ductal... Invasive Ductal... Medullary Ducta... Mucinous Ductal... Papillary Ducta... Progesterone Re... Stage IA Breast... Stage IB Breast... Tubular Ductal ... | accelerated par... intensity-modul... image-guided ra... therapeutic con... | 50 Years - | Ohio State University Comprehensive Cancer Center | |
| Ultra-hypofractionated Radiotherapy in Breast Cancer Patients | NCT05586256 | Female Breast C... | ultra-hypofract... | 18 Years - 99 Years | University Of Perugia | |
| Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC) | NCT02950259 | Breast Neoplasm Breast Neoplasm... Triple Negative... | Cyclophosphamid... Indomethacin Omeprazole Multivitamin | - | Providence Health & Services | |
| A Study to Compare Administration Schedules of G-CSF (Filgrastim) for Primary Prophylaxis of Febrile Neutropenia | NCT02816164 | Early Stage Bre... | Neupogen | 19 Years - | Ottawa Hospital Research Institute | |
| Preoperative Cisplatin in Early Stage Breast Cancer | NCT00148694 | Breast Cancer | Cisplatin | 18 Years - | Dana-Farber Cancer Institute | |
| ABUS for Early-stage Breast Cancer | NCT04607473 | Early Stage Bre... | automated breas... | 25 Years - 69 Years | Samsung Medical Center | |
| Partial Breast Irradiation With Interstitial High Dose Rate Brachytherapy | NCT00499057 | Breast Cancer | interstitial hi... | 40 Years - 85 Years | University Of Perugia | |
| Partial Breast Irradiation With Interstitial High Dose Rate Brachytherapy | NCT00499057 | Breast Cancer | interstitial hi... | 40 Years - 85 Years | University Of Perugia | |
| Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer | NCT03155997 | Breast Cancer | Abemaciclib Standard Adjuva... | 18 Years - | Eli Lilly and Company | |
| Nanoparticle Albumin-Bound (Nab) Paclitaxel/Cyclophosphamide in Early-Stage Breast Cancer | NCT00629499 | Breast Cancer | nab paclitaxel Cyclophosphamid... Trastuzumab | 18 Years - | SCRI Development Innovations, LLC | |
| SPI-2012 vs Pegfilgrastim in Management of Neutropenia in Breast Cancer Participants With Docetaxel and Cyclophosphamide | NCT02953340 | Neutropenia Breast Cancer | SPI-2012 Pegfilgrastim Docetaxel Cyclophosphamid... | 18 Years - | Spectrum Pharmaceuticals, Inc |
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