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Brief Title: Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients
Official Title: Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients
Study ID: NCT01015274
Brief Summary: The long-term objective of this research is to develop a non-invasive approach for early assessment of which patients are at high risk for future development of skeletal muscle atrophy. The investigators hypothesize that the rate constant for the terminal portion of the isotope decay curve following ingestion of a single oral dose of deuterated-3-methylhistidine (D-3MH) provides an accurate measure of this increased risk and that this rate constant can be measured non-invasively from timed spot urine samples.
Detailed Description:
Minimum Age: 30 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: Yes
University of Texas Medical Branch, Galveston, Texas, United States
Name: Morteza Janghorbani, Ph.D.
Affiliation: BIOCHEMANALYSIS CORPORATION
Role: PRINCIPAL_INVESTIGATOR
Name: Melinda Sheffield-Moore, Ph.D.
Affiliation: University of Texas
Role: STUDY_DIRECTOR