Spots Global Cancer Trial Database for cachexia
Every month we try and update this database with for cachexia cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Skeletal Muscle Expression of Myostatin and Cancer of Digestive System Associated Cachexia | NCT03172403 | Cancer of Diges... | Height and weig... Blood samples Skeletal muscle... Skeletal muscle... Muscle biopsy | 40 Years - 80 Years | Centre Hospitalier Universitaire de Saint Etienne | |
| Adenosine Triphosphate in Treating Patients With Advanced Solid Tumors | NCT00014248 | Cachexia Unspecified Adu... | adenosine triph... quality-of-life... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy | NCT00486304 | Cachexia Head and Neck C... Weight Changes | ADD Placebo | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
| Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms | NCT05307367 | Cachexia Neoplasms Exercise Metabolism Body Compositio... Insulin Resista... Physical Functi... Quality of Life Sarcopenia Caregivers Adipose Tissue Muscle, Skeleta... Patient Reporte... Gastrointestina... Proteomics Lipidomics Epigenomics Mitochondria | Exercise traini... | 18 Years - 100 Years | University of Copenhagen | |
| Safety, Efficacy and Pharmacokinetics of ALD518 in Patients With Non-Small Cell Lung Cancer-related Fatigue and Cachexia | NCT00866970 | NSCLC Fatigue Cachexia | ALD518 ALD518 ALD518 Infusion of 0.9... | 18 Years - | CSL Behring | |
| Improvement of Neuromuscular Function, Fatigue and Quality of Life by Optimizing Muscle Building and Nutrition in Colorectal Cancer: a Pilot Study | NCT04136249 | Cancer Cachexia; Cance... | Over physical a... | 18 Years - | Ramsay Générale de Santé | |
| Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma | NCT05376592 | Pancreas Adenoc... Cachexia | 18 Years - | Wake Forest University Health Sciences | ||
| Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Lung Cancer Patients | NCT00851448 | Cachexia Cancer | oral nutritiona... | 18 Years - 75 Years | Fresenius Kabi | |
| Investigation of the Gut Microbiota in Patients With Acute Myeloid Leukemia | NCT03881826 | Acute Myeloid L... Cachexia | collection of c... | 18 Years - 75 Years | Université Catholique de Louvain | |
| Mitochondrial Respiratory Function in Mammalian Skeletal Muscle | NCT02650570 | Cancer Cachexia | 30 Years - 60 Years | The University of Texas Medical Branch, Galveston | ||
| Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients | NCT01015274 | Cachexia | 30 Years - 75 Years | The University of Texas Medical Branch, Galveston | ||
| Development of a Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients | NCT00994669 | Cachexia | 30 Years - 85 Years | The University of Texas Medical Branch, Galveston | ||
| Development of a Screening Tool to Detect and Stage Cachectic Cancer Patients | NCT01533909 | Cachexia | 18 Years - 95 Years | Universitaire Ziekenhuizen KU Leuven | ||
| The Impact of Oligo-Fucoidan in Cancer Cachexia and Sarcopenia | NCT05623852 | Cachexia | fucoidan | 20 Years - 90 Years | Taipei Medical University WanFang Hospital | |
| The Role of Ghrelin in Cancer Cachexia | NCT01505764 | Cancer Cachexia | Anamorelin HCl Placebo | 18 Years - | VA Office of Research and Development | |
| Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia | NCT04803305 | Non-small Cell ... Pancreatic Canc... Colorectal Canc... Prostate Cancer Breast Cancer Ovarian Cancer Loss of Appetit... Fatigue Cachexia Anorexia | PF-06946860 Placebo for PF-... | 18 Years - | Pfizer | |
| Development of a Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients | NCT00994669 | Cachexia | 30 Years - 85 Years | The University of Texas Medical Branch, Galveston | ||
| Multimodal Treatment Strategy for Cancer Cachexia | NCT00625742 | Advanced Cancer Cachexia | Graded Resistan... Aerobic Exercis... Melatonin Juven Atenolol Ibuprofen | 18 Years - | M.D. Anderson Cancer Center | |
| Identify microRNAs in Cachexia in Pancreatic Carcinoma | NCT05275075 | Resectable Panc... | Pancreatic canc... | 18 Years - | University of Oklahoma | |
| Food Reward in Cachexia Induced by Acute or Chronic Disease | NCT02798003 | Cachexia Chronic Obstruc... Non-small Cell ... Pancreatic Canc... | Functional magn... | 18 Years - | Maastricht University Medical Center | |
| Muscle Wasting in Hemodialysis Patient | NCT03583177 | Muscle Atrophy ... | No intervention | 18 Years - 75 Years | University Hospital, Clermont-Ferrand | |
| Patient Recorded Indexing Measurements | NCT05899205 | Cachexia Cancer Weight, Body | 18 Years - 80 Years | Academisch Ziekenhuis Maastricht | ||
| Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care. | NCT03283488 | Cachexia; Cance... Anorexia | Mirtazapine Megestrol | 50 Years - | University of Sao Paulo | |
| Perioperative Glutamine Supplementation and Cachexia | NCT05023499 | Glutamine; Meta... Cachexia | SYMPT-X Glutami... | 20 Years - | National Taiwan University Hospital | |
| Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients. | NCT05380479 | Anorexia | Mirtazapine Megestrol Aceta... | 18 Years - 70 Years | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | |
| Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases | NCT04067167 | Cancer Cancer Cachexia Inflammation Muscular Atroph... | WB-EMS (Sham-in... WB-EMS Free WB-EMS Flexi band resi... | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Prevalence of Malnutrition in Oncology (PreMiO) | NCT01622036 | Malnutrition Pre-cachexia Cancer | 18 Years - | University of Roma La Sapienza | ||
| Olanzapine in Patients With Advanced Cancer and Weight Loss | NCT00489593 | Advanced Cancer Weight Loss | Olanzapine | - | M.D. Anderson Cancer Center | |
| Multimodal Intervention for Patients With Non-small Cell Lung Cancer | NCT04161794 | Cachexia; Cance... | multimodal | 18 Years - | Aalborg University Hospital | |
| Brown Adipose Tissue Activity and Energy Metabolism in Cachexia | NCT02500004 | Cachexia Neoplasms Pulmonary Disea... Pancreatic Neop... | 18F-FDG PET-MRI... DXA scanning Abdominal subcu... Blood sampling Indirect calori... Accelerometry Double-labeled ... | 30 Years - | Maastricht University Medical Center | |
| Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases | NCT04067167 | Cancer Cancer Cachexia Inflammation Muscular Atroph... | WB-EMS (Sham-in... WB-EMS Free WB-EMS Flexi band resi... | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1) | NCT01387269 | Cachexia Non-Small Cell ... | Anamorelin HCl Placebo | 18 Years - | Helsinn Therapeutics (U.S.), Inc | |
| Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 2) | NCT01387282 | Cachexia Non-Small Cell ... | Anamorelin HCl Placebo | 18 Years - | Helsinn Therapeutics (U.S.), Inc | |
| Safety and Efficacy of RC-1291 HCl in Patients With Cancer Related Anorexia and Weight Loss | NCT00219817 | Cancer Cachexia | RC-1291 HCl | 18 Years - | Helsinn Therapeutics (U.S.), Inc | |
| Brown Adipose Tissue Activity and Energy Metabolism in Cachexia | NCT02500004 | Cachexia Neoplasms Pulmonary Disea... Pancreatic Neop... | 18F-FDG PET-MRI... DXA scanning Abdominal subcu... Blood sampling Indirect calori... Accelerometry Double-labeled ... | 30 Years - | Maastricht University Medical Center | |
| Multimodal Intervention for Patients With Non-small Cell Lung Cancer | NCT04161794 | Cachexia; Cance... | multimodal | 18 Years - | Aalborg University Hospital | |
| Food Reward in Cachexia Induced by Acute or Chronic Disease | NCT02798003 | Cachexia Chronic Obstruc... Non-small Cell ... Pancreatic Canc... | Functional magn... | 18 Years - | Maastricht University Medical Center | |
| Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer | NCT00031785 | Anorexia Cachexia Lung Cancer | megestrol aceta... radiation thera... | 18 Years - 120 Years | Wake Forest University Health Sciences | |
| Ruxolitinib for Cancer Cachexia | NCT04906746 | Stage IV Non-sm... Cachexia | Identify any do... | 18 Years - | University of Texas Southwestern Medical Center | |
| Brown Adipose Tissue Activity and Energy Metabolism in Cachexia | NCT02500004 | Cachexia Neoplasms Pulmonary Disea... Pancreatic Neop... | 18F-FDG PET-MRI... DXA scanning Abdominal subcu... Blood sampling Indirect calori... Accelerometry Double-labeled ... | 30 Years - | Maastricht University Medical Center | |
| Prevalence of Hypogonadism in Male Cancer Patients | NCT00472940 | Cancer Hypogonadism | 18 Years - | Baylor College of Medicine | ||
| The Role of Ghrelin in Cancer Cachexia | NCT01505764 | Cancer Cachexia | Anamorelin HCl Placebo | 18 Years - | VA Office of Research and Development | |
| Strength Training on Pancreatic Cancer | NCT01395563 | Pancreatic Neop... Cachexia Myopathy | strength traini... | - | German Cancer Research Center | |
| Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced and Incurable Solid Tumors | NCT05705492 | Advanced Malign... | Biospecimen Col... Computed Tomogr... Olanzapine Placebo Adminis... Questionnaire A... | 18 Years - | OHSU Knight Cancer Institute | |
| Mitochondria Preservation by Exercise Training: a Targeted Therapy for Cancer and Chemotherapy-induced Cachexia | NCT05028192 | Cachexia Rectal Cancer | no intervention | 18 Years - 75 Years | University of Turin, Italy | |
| Ruxolitinib for Cancer Cachexia | NCT04906746 | Stage IV Non-sm... Cachexia | Identify any do... | 18 Years - | University of Texas Southwestern Medical Center | |
| Haelan and Nutrition in Cancer Patients | NCT00558558 | Anorexia Weight Loss Cachexia | Haelan | - | M.D. Anderson Cancer Center | |
| Computerized Questionnaires in Assessing Symptoms, Pain, Depression, and Physical Function in Patients With Metastatic and/or Advanced Locoregional Cancer | NCT00972634 | Cachexia Depression Pain Unspecified Adu... | computer-assist... questionnaire a... assessment of t... quality-of-life... | 18 Years - | Norwegian University of Science and Technology | |
| Megestrol and Exercise in Treating Patients With Cancer-Related Weight Loss | NCT00004912 | Cachexia Fatigue Unspecified Adu... | megestrol aceta... physical therap... | 18 Years - | Northwestern University | |
| Development of a Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients | NCT00994669 | Cachexia | 30 Years - 85 Years | The University of Texas Medical Branch, Galveston | ||
| Improvement of Neuromuscular Function, Fatigue and Quality of Life by Optimizing Muscle Building and Nutrition in Colorectal Cancer: a Pilot Study | NCT04136249 | Cancer Cachexia; Cance... | Over physical a... | 18 Years - | Ramsay Générale de Santé | |
| Mitochondrial Respiratory Function in Mammalian Skeletal Muscle | NCT02650570 | Cancer Cachexia | 30 Years - 60 Years | The University of Texas Medical Branch, Galveston | ||
| Pilot Study of APD209 in Cancer Cachexia | NCT00895726 | Cancer-related ... | APD209 | 18 Years - | Acacia Pharma Ltd | |
| Multimodal Program for Cancer Related Cachexia Prevention | NCT04627376 | Neoplasms Cancer Cachexia Malnutrition Educational Pro... | Multimodal educ... | 18 Years - | Cyprus University of Technology | |
| Early Diagnosis of Gastric Cancer Cachexia | NCT06277986 | Cachexia | cachexia | 18 Years - | Xijing Hospital | |
| Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite | NCT00031707 | Anorexia Cachexia | eicosapentaenoi... megestrol aceta... placebo | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Slimming Myokines, Cancers,Nutritional and Psychology Support | NCT05278078 | Cancer | psychological s... nutritional edu... psychological s... no intervation | 50 Years - 80 Years | T.C. ORDU ÜNİVERSİTESİ | |
| Nutritional Problems and Changes in Body Composition in Patients With Non-small Cell Lung Cancer (LEKS) | NCT01865903 | Weight Loss Cachexia | 18 Years - | Oslo University Hospital | ||
| Resting Energy Expenditure in Palliative Cancer Patients | NCT06206785 | Cancer Cachexia | 18 Years - | Norwegian University of Science and Technology | ||
| Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients | NCT00513357 | Gastrointestina... Lung Cancer | Melatonin Placebo | 18 Years - | M.D. Anderson Cancer Center | |
| A Dose Escalation Study of AV-380 in Metastatic Cancer Patients With Cachexia | NCT05865535 | Cachexia | AV-380 | 18 Years - | AVEO Pharmaceuticals, Inc. | |
| Effectiveness of Nutritional Counselling and "Improved Atta" Supplementation in Cachexic Adult Indian Cancer Patients | NCT02561143 | Cachexia Cancer | Improved Atta Wheat flour Physical activi... Nutritional cou... | 18 Years - | University of Westminster | |
| A Feasibility Study of Multimodal Exercise/Nutrition/Anti-inflammatory Treatment for Cachexia - the Pre-MENAC Study | NCT01419145 | Cancer Cachexia | Multimodal inte... Standard care | 18 Years - 80 Years | Norwegian University of Science and Technology | |
| Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer | NCT00046904 | Anorexia Cachexia Unspecified Adu... | etanercept | 18 Years - | Mayo Clinic | |
| Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15 | NCT05546476 | Non-small Cell ... Pancreatic Canc... Colorectal Canc... Loss of Appetit... Fatigue Cachexia | ponsegromab Placebo for pon... | 18 Years - | Pfizer | |
| Is Clarithromycin a Potential Treatment for Cachexia in People With Lung Cancer? | NCT02416570 | Cachexia Lung Cancer | Clarithromycin Placebo | 18 Years - | University of Nottingham | |
| Individual Dose-escalated Bi-daily Subcutaneously (sc) Ghrelin in Cancer Cachexia: a Phase I/II Study | NCT00933361 | Advanced Cancer Cachexia | ghrelin | 18 Years - | Cantonal Hospital of St. Gallen | |
| Vitamin D and Pre Cachexia and Cancer Cachexia in Epithelial Ovarian Cancer | NCT04864431 | Epithelial Ovar... | Vitamin D Placebo | 18 Years - 60 Years | Indonesia University | |
| Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract | NCT03111771 | Cancer of Upper... Cachexia | carcinological ... cervical surger... | 18 Years - 80 Years | University Hospital, Clermont-Ferrand | |
| Prevalence of Hypogonadism in Male Cancer Patients | NCT00472940 | Cancer Hypogonadism | 18 Years - | Baylor College of Medicine | ||
| Routine Evaluation of People Living With Cancer | NCT04406662 | Cachexia; Cance... Advanced Cancer Quality of Life | 18 Years - | University of Edinburgh | ||
| MalnutritiOn Assessment With biOelectrical impedaNce Analysis in gastRic Cancer patIentS Undergoing Multimodal trEatment | NCT05723718 | Gastric Cancer Gastric Adenoca... Malnutrition Cachexia | Observational S... | 18 Years - 100 Years | Medical University of Lublin | |
| Pilot Project for Cardiopulmonary and Functional Evaluation in Patients With Pancreatic Cancer Associated Cachexia | NCT02580422 | Cachexia Pancreatic Canc... | - | Indiana University | ||
| Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05) | NCT00040885 | Anorexia Cachexia Fatigue Lung Cancer | infliximab docetaxel placebo | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Brown Adipose Tissue Activity and Energy Metabolism in Cachexia | NCT02500004 | Cachexia Neoplasms Pulmonary Disea... Pancreatic Neop... | 18F-FDG PET-MRI... DXA scanning Abdominal subcu... Blood sampling Indirect calori... Accelerometry Double-labeled ... | 30 Years - | Maastricht University Medical Center | |
| Impact of Nutritional Intervention in Indian Female Cancer Cachexia Patients | NCT02350855 | Cachexia Cancer | Improved Atta Nutritional cou... Physical activi... | 18 Years - | University of Westminster | |
| The Role of Muscle Cachexia in Pancreatic Cancer | NCT02515513 | Pancreas Cancer | Muscle Tissue B... | 18 Years - 80 Years | University of Florida | |
| Impact of Nutritional Intervention in Indian Female Cancer Cachexia Patients | NCT02350855 | Cachexia Cancer | Improved Atta Nutritional cou... Physical activi... | 18 Years - | University of Westminster | |
| Effects of WB-EMS and Dietetic Treatment on Cancer Patients | NCT02293239 | Cancer Cancer Cachexia Weight Loss Muscle Loss Muscle Weakness | Whole-Body Elec... | 18 Years - | University of Erlangen-Nürnberg Medical School | |
| Novel Form of Nutritional Supplementation in Cancer Patients | NCT03561610 | Cancer Malnutrition Cachexia | sip feed gumdrops | 18 Years - | University of Erlangen-Nürnberg Medical School |
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