Spots Global Cancer Trial Database for Correlation Between Myocardial Injury and Intestinal Flora Changes Associated With Oncology Drug Therapy

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Trial Identification

Brief Title: Correlation Between Myocardial Injury and Intestinal Flora Changes Associated With Oncology Drug Therapy

Official Title: Correlation Between Early Myocardial Injury and Intestinal Flora Changes Associated With Oncology Drug Therapy

Study ID: NCT05728788

Conditions

Cancer Therapy-related Cardiovascular Toxicity

Interventions

Antitumor drugs

Study Description

Brief Summary: The purpose of this study was to explore the relationship between early myocardial injury caused by tumor drug therapy and intestinal microbial structure changes by echocardiographic two-dimensional speckle tracking technique and intestinal microflora structure detection.

Detailed Description: This is a monocentric prospective cohort study in which 50 patients treated for malignant tumors will be included. All participants will be followed for 6 months after the initiation of oncology drug therapy. Echocardiography and 2D speckle tracking will be performed and stool and blood samples will be tested before treatment initiation and at 3 and 6 months after initiation.