Spots Global Cancer Trial Database for Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells

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Trial Identification

Brief Title: Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells

Official Title: Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells

Study ID: NCT01022723

Conditions

Cancer

Interventions

Study Description

Brief Summary: To evaluate the efficiency of a microdevice for circulating tumor cells isolation and to correlate the circulating titre with response and progression.

Detailed Description: * Validate the clinical use of a mircofluidic device to capture circulating timor cells from a broad range of tumor types * Characterize and identify these circulating tumor cells and demostrate cell viability with this capture method * Apply this technology in clinically relevant settings and correlate to response to treatment and disease progression * Elucidate predictive and pharmacodynamic biomarkers in the context of early phase trials of novel therapeutics