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Spots Global Cancer Trial Database for Characterization of Methylation Patterns in Cancer and Non-Cancer cfDNA

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Trial Identification

Brief Title: Characterization of Methylation Patterns in Cancer and Non-Cancer cfDNA

Official Title: Characterization of Methylation Patterns in Cancer and Non-Cancer cfDNA, An Observational Multicenter Study

Study ID: NCT04264767

Interventions

Blood collection

Study Description

Brief Summary: Nucleix EpiCheck® tests analyzes the methylation pattern in a panel of DNA methylation biomarkers and determines whether this pattern is consistent with cancer under test or with non-cancer tissue. This study is being performed as part of the development process of the Pan Cancer EpiCheck test which includes the identification of different methylation profiles in various cancer types and healthy controls.

Detailed Description: The aim of this study is to characterize methylation patterns that will distinguish cancer from normal samples and will be able to recognize the origin of the cancer by collecting cfDNA (circulating free DNA) from blood samples collected from patients with a new diagnosis of cancer and from healthy volunteers who do not have diagnosis or history of cancer. Identifying those methylation patterns may assist in the development of blood test that will be able to detect the presence and the origin of wide range of human cancers

Eligibility

Minimum Age: 22 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

Los Angeles Hematology Oncology Medical Group - Wilson Terrace, Glendale, California, United States

Los Angeles Hematology Oncology Medical Group - Good Samaritan Medical Offices, Los Angeles, California, United States

Sourasky Medical Center, Tel Aviv, , Israel

Contact Details

Name: Shmulik Adler

Affiliation: Nucleix Ltd.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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