Spots Global Cancer Trial Database for methylation
Every month we try and update this database with for methylation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Markers for Early Detection of Prostate Cancer | NCT00340717 | Prostate Cancer | 40 Years - 75 Years | National Institutes of Health Clinical Center (CC) | ||
| The Red Blood Cells Based Blood Test for Lung Cancer EARLY Detection | NCT05380999 | Lung Cancer Red Blood Cells Methylation | Methylation tes... | 18 Years - | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | |
| Specific Methylation Profiles in HNSCC | NCT04567056 | Head and Neck S... | Blood sample | 18 Years - | Aalborg University Hospital | |
| Characterization of Methylation Patterns in Cancer and Non-Cancer cfDNA | NCT04264767 | Cancer Solid Tumor Hematologic Neo... | Blood collectio... | 22 Years - 80 Years | Nucleix Ltd. | |
| a PROspective Case Control Study to Develop and Validate a Blood Test FOr mUlti-caNcers Early Detection（PROFOUND） | NCT06217900 | Cancer | 40 Years - 74 Years | Shanghai Weihe Medical Laboratory Co., Ltd. | ||
| Analysis of Olaparib Response in Patients With BRCA1 and/or 2 Promoter Methylation Diagnosed of Advanced Breast Cancer | NCT03205761 | Advanced Breast... | Olaparib | 18 Years - | Spanish Breast Cancer Research Group | |
| Dynamic Monitoring of ctDNA Methylation to Predict Relapse in Colorectal Cancer After Radical Resection (POSTCA) | NCT03737539 | Colorectal Canc... Circulating Tum... Surveillance Methylation | Multigene methy... | 18 Years - | Fudan University | |
| Characterization of Methylation Patterns in Cancer and Non-Cancer cfDNA | NCT04264767 | Cancer Solid Tumor Hematologic Neo... | Blood collectio... | 22 Years - 80 Years | Nucleix Ltd. | |
| PTEN and IGFBP-3 Correlation in Ovarian Carcinoma Invasion | NCT00173407 | Ovarian Cancer | immunohistochem... | 21 Years - 80 Years | National Taiwan University Hospital | |
| Cell-free DNA Methylation Markers for Cancer Screening | NCT03096938 | Cancer Screenin... | methylation mar... | 40 Years - 74 Years | Sun Yat-sen University | |
| Serum DNA Analysis: Potential Application for Diagnosis and Prognosis in Brain Cancer. | NCT00265174 | Primary Brain T... | - | Hadassah Medical Organization | ||
| Characterization of Methylation Patterns in Hepatocellular Carcinoma | NCT04264754 | Hepatocellular ... Hepatocellular ... Cirrhosis | Blood collectio... | 22 Years - | Nucleix Ltd. | |
| Study of Three Different Schedules of Low-Dose Decitabine in Myelodysplastic Syndrome (MDS) | NCT00067808 | Myelodysplastic... Chronic Myelomo... | Decitabine Decitabine Decitabine | - | M.D. Anderson Cancer Center | |
| Multiplex Analysis of Circulating Tumor DNA | NCT03301961 | Carcinoma Non-small-cell ... Lung Neoplasm | 18 Years - | Peking University People's Hospital | ||
| LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML) | NCT00691938 | Leukemia, Myelo... Myelodysplastic... | LBH589 Decitabine | 60 Years - | Washington University School of Medicine | |
| Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic Acid | NCT02608736 | Head and Neck S... | Valproic Acid Placebo | 18 Years - | Barretos Cancer Hospital | |
| Cell-free DNA Methylation Markers for Cancer Screening | NCT03096938 | Cancer Screenin... | methylation mar... | 40 Years - 74 Years | Sun Yat-sen University | |
| Clinical Research on Dynamic Monitoring MRD Via Plasma ctDNA After Systemic Therapy of Hepatocellular Carcinoma | NCT06178809 | Hepatocellular ... | 18 Years - 80 Years | Singlera Genomics Inc. | ||
| GNB4 and Riplet Gene Methylation Combined Detection Kit (Fluorescence PCR Method) | NCT05668793 | Hepatocellular ... | GNB4 and Riplet... | 18 Years - | Wuhan Ammunition Life-tech Co., Ltd | |
| Characterization of Methylation Patterns in Hepatocellular Carcinoma | NCT04264754 | Hepatocellular ... Hepatocellular ... Cirrhosis | Blood collectio... | 22 Years - | Nucleix Ltd. | |
| Utility of Bladder EpiCheck for Detection of Recurrent Urothelial Carcinoma | NCT02647112 | Bladder Cancer | Bladder EpiChec... | 22 Years - 100 Years | Nucleix Ltd. | |
| Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins | NCT01563874 | Lymphoma Lymphoid Hyperp... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML) | NCT00691938 | Leukemia, Myelo... Myelodysplastic... | LBH589 Decitabine | 60 Years - | Washington University School of Medicine | |
| Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic Acid | NCT02608736 | Head and Neck S... | Valproic Acid Placebo | 18 Years - | Barretos Cancer Hospital | |
| Fecal DNA Methylation Test for Colorectal Cancer Screening | NCT04823793 | Colorectal Canc... Colorectal Aden... | Stool DNA methy... | 40 Years - 79 Years | Tri-Service General Hospital | |
| KCNA3 and OTOP2 Gene Methylation Combined Detection Kit (Fluorescent PCR Method) | NCT05680077 | Esophageal Neop... | KCNA3 and OTOP2... | 40 Years - | Wuhan Ammunition Life-tech Co., Ltd | |
| Diet and Nutrition Pilot Study for Chinese Adolescents and Their Mothers | NCT01517139 | Methylation Body Compositio... Physical Activi... Puberty | 15 Years - 45 Years | National Institutes of Health Clinical Center (CC) | ||
| Dynamic Monitoring of ctDNA Methylation to Predict Relapse in Colorectal Cancer After Radical Resection (POSTCA) | NCT03737539 | Colorectal Canc... Circulating Tum... Surveillance Methylation | Multigene methy... | 18 Years - | Fudan University | |
| Diet and Nutrition Pilot Study for Chinese Adolescents and Their Mothers | NCT01517139 | Methylation Body Compositio... Physical Activi... Puberty | 15 Years - 45 Years | National Institutes of Health Clinical Center (CC) | ||
| Molecular Analysis of Endoscopic Cytology Samples Supernatant in Pulmonary Nodules | NCT05306912 | Lung Cancer Lung; Node | Blood samples | 18 Years - | University Hospital, Toulouse | |
| Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer | NCT01896856 | Previously Trea... | SGI-110 Dose Es... Regorafenib TAS-102 SGI-110 Irinotecan | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Stage II/III Colorectal Cancer Recurrence | NCT06314958 | Colorectal Canc... Colorectal Aden... Colorectal Canc... Colorectal Canc... Colorectal Canc... | CENSURE | 18 Years - | City of Hope Medical Center | |
| A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML | NCT01861002 | Lymphoblastic L... Myelogenous Leu... | Azacytidine Fludarabine Cytarabine Intrathecal (IT... Intrathecal Met... | 1 Year - 21 Years | Therapeutic Advances in Childhood Leukemia Consortium | |
| Multiplex Analysis of Circulating Tumor DNA | NCT03301961 | Carcinoma Non-small-cell ... Lung Neoplasm | 18 Years - | Peking University People's Hospital | ||
| Discovery and Validation of Plasma DNA Methylation Biomarker for Detection of Stomach Cancer | NCT03076567 | Stomach Cancer Gastric Cancer | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins | NCT01563874 | Lymphoma Lymphoid Hyperp... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Cell-free DNA Methylation Markers for Cancer Screening | NCT03096938 | Cancer Screenin... | methylation mar... | 40 Years - 74 Years | Sun Yat-sen University | |
| cfDNA Methylation Assay for Clinical Evaluation of Patients With Stage IA Lung Cancer After Ablation Operation | NCT04413656 | Lung Cancer | ablation surgery | 18 Years - 85 Years | Shanghai Chest Hospital |
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