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Brief Title: Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
Official Title: Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
Study ID: NCT05823740
Brief Summary: The primary objective of this study is to evaluate the feasibility and acceptability of obtaining repeated measurements of lean muscle mass, physical function, and biological aging in children receiving active cancer therapy. The secondary objective is to evaluate the feasibility of using the D3-creatine dilution method (D3Cr) to measure skeletal muscle mass in children with cancer. Assessments will be collected at diagnosis, once during active treatment, and end of treatment in coordination with routine imaging to monitor changes in study outcomes during active cancer treatment. Key sociodemographic, treatment and health-related factors will be abstracted from the medical record.
Detailed Description:
Minimum Age: 8 Years
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States
Name: Jessica Benjamin-Eze
Affiliation: UNC Lineberger Comprehensive Cancer Center
Role: PRINCIPAL_INVESTIGATOR