Spots Global Cancer Trial Database for pediatric
Every month we try and update this database with for pediatric cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Enteral Nutrition in Cancer Patients | NCT01304446 | Malnutrition Cancer | industrialized ... | 1 Year - | Grupo de Apoio ao Adolescente e a Crianca com Cancer | |
| Distracting Through Procedural Pain and Distress | NCT04892160 | Chronic Illness Hematologic Mal... Bone Marrow Tra... Oncology Sickle Cell Dis... | Guided Imagery Virtual Reality | 8 Years - 25 Years | Medical College of Wisconsin | |
| Treatment for Advanced B-Cell Lymphoma | NCT01859819 | Diffuse Large C... Burkitt's Lymph... High Grade B-ce... | Rituximab IT Cytarabine | 3 Years - 31 Years | New York Medical College | |
| This is a Phase 1 Study of Eribulin Mesylate in Pediatric Participants With Recurrent or Refractory Solid Tumors (Excluding [Central Nervous System] CNS), Including Lymphomas | NCT02171260 | Pediatrics Solid Tumors | Eribulin Mesyla... | 6 Months - 17 Years | Eisai Inc. | |
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | NCT05106296 | Ependymoma Medulloblastoma Glioblastoma Primary Brain T... | Ibrutinib Indoximod Cyclophosphamid... Etoposide | 12 Years - 25 Years | Augusta University | |
| Granulocyte Transfusions After Umbilical Cord Blood Transplant | NCT05425043 | Pediatric Cance... | Granulocytes | - 16 Years | University of Manchester | |
| Late Effects of Treatment for Sarcomas in Children | NCT00006515 | Sarcoma | 7 Years - | National Institutes of Health Clinical Center (CC) | ||
| Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery | NCT04344626 | Epilepsy Focal Cortical ... Tuberous Sclero... Hemimegalenceph... Polymicrogyria Rasmussen Encep... Sturge-Weber Sy... Gliosis Stroke Tumor, Brain | Intra-operative... | - | University of California, Los Angeles | |
| A Pilot Study of Allopurinol As A Modifier of 6-MP Metabolism in Pediatric ALL | NCT02046694 | Acute Lymphobla... | Allopurinol | - 30 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Study of Single Agent Perifosine for Recurrent Pediatric Solid Tumors | NCT00776867 | Solid Tumors | perifosine | - 21 Years | Memorial Sloan Kettering Cancer Center | |
| Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia | NCT04898894 | Acute Leukemia ... Acute Myeloid L... Refractory Acut... Refractory Acut... | Venetoclax Selinexor Cytarabine Fludarabine Filgrastim Methotrexate methotrexate/hy... | 2 Years - 30 Years | St. Jude Children's Research Hospital | |
| A Pharmacokinetic (PK) Study of Nilotinib in Pediatric Patients With Philadelphia Chromosome-positive (Ph+) Chronic Myelogenous Leukemia (CML) or Acute Lymphoblastic Leukemia (ALL) | NCT01077544 | Chronic Myeloid... Acute Lymphobla... | Nilotinib | 1 Year - 17 Years | Novartis | |
| Comparative Pharmacokinetics of a Compounded 6-mercaptopurine Liquid Formulation Preparation and Tablets | NCT01324336 | Acute Lymphobla... | 6-Mercaptopurin... | 4 Years - 17 Years | Children's Mercy Hospital Kansas City | |
| Auditory Brainstem Implant (ABI) in Pediatric Non-Neurofibromatosis Type 2 Subjects | NCT01864291 | Bilateral Heari... | Nucleus 24 (dis... | 18 Months - 17 Years | Massachusetts Eye and Ear Infirmary | |
| A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma | NCT05255601 | Lymphoma, Non-H... Hodgkin Disease | Relatlimab Nivolumab | - 30 Years | Bristol-Myers Squibb | |
| Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors | NCT04337177 | Solid Tumors Neuroblastoma Rhabdomyosarcom... Ewing Sarcoma Hepatoblastoma Medulloblastoma | VAL-413 Temozolomide | 1 Year - 30 Years | Valent Technologies, LLC | |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma | NCT03615404 | Glioblastoma Malignant Gliom... Medulloblastoma... Pediatric Gliob... Pediatric Brain... Pediatric Brain... | CMV-DCs with GM... Td (tetanus tox... | 0 Years - 35 Years | Duke University | |
| Autologous Stem Cell Rescue With CD133+ Selected Cells in High-Risk Neuroblastoma | NCT00539500 | Neuroblastoma | Carboplatin Etoposide Melphalan Stem Cell Infus... ClinicMACS | - | M.D. Anderson Cancer Center | |
| Topotecan, Ifosfamide and Carboplatin in Children and Young Adults With Solid Tumors | NCT00502892 | Solid Tumors | Topotecan Ifosfamide Carboplatin | - 45 Years | M.D. Anderson Cancer Center | |
| Estimating the Global Need for Palliative Care for Children | NCT02553148 | Cancer Congenital Anom... Cardiovascular ... HIV | Need for childr... | - 19 Years | International Children's Palliative Care Network | |
| Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy. | NCT03605186 | Oral Mucositis ... | Chamomile oral ... Oral cryotherap... | 6 Years - 18 Years | Cairo University | |
| Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Supratentorial Brain Tumors | NCT04738162 | Brain Tumor, Pe... | 5-Aminolevulini... | 3 Years - 17 Years | Universität Münster | |
| A Pharmacokinetic Study of Pediatric Micafungin Prophylaxis | NCT02057289 | Immunocompromis... Bone Marrow Tra... Cancer | Micafungin | 6 Months - 10 Years | Children's Hospital Medical Center, Cincinnati | |
| NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors | NCT01875601 | Solid Tumors Brain Tumors Sarcoma Pediatric Cance... Neuroblastoma | Recombinant hum... NK Cell Infusio... | 2 Years - 29 Years | National Institutes of Health Clinical Center (CC) | |
| Eligibility Screening for a NCI Pediatric Oncology Branch Research Study | NCT00026780 | Ewing Sarcoma Osteosarcoma Neuroblastoma Acute Lymphobla... Neurofibromatos... | - 35 Years | National Institutes of Health Clinical Center (CC) | ||
| An Open-label Extension Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis | NCT06435312 | Generalized Mya... | Zilucoplan | 12 Years - | UCB Pharma | |
| Epigenetic Reprogramming in Relapse/Refractory AML | NCT03263936 | Acute Myelogeno... | Decitabine Vorinostat Filgrastim (G-C... Fludarabine Cytarabine | 1 Year - 25 Years | Therapeutic Advances in Childhood Leukemia Consortium | |
| Using of Virtual Reality to Relieve Procedural Pain in Pediatric Oncology. | NCT05042479 | Hematologic Mal... Hematologic Non... Solid Tumor, Ch... Child, Only | Usual distracti... Virtual reality Choice between ... | 7 Years - 18 Years | Nantes University Hospital | |
| Improving Quality and Consistency in Family Education Prior to First Discharge Following Pediatric Cancer Diagnosis | NCT03752801 | Oncology | - | The Hospital for Sick Children | ||
| AC220 for Children With Relapsed/Refractory ALL or AML | NCT01411267 | Lymphoblastic L... Myelogenous Leu... | AC220 Cytarabine Etoposide Methotrexate | 1 Month - 21 Years | Therapeutic Advances in Childhood Leukemia Consortium | |
| Nebulized Amphotericin B Lipid Complex in Invasive Pulmonary Aspergillosis in Paediatric Patients With Acute Leukaemia | NCT01615809 | Invasive Pulmon... Lymphoblastic L... Myeloblastic Le... Lymphoblastic L... Myeloblastic Le... | AMPHOTERICIN B | 3 Years - 17 Years | Fundació Sant Joan de Déu | |
| A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomide | NCT03495921 | Ewing Sarcoma Ewing Family of... Ewing's Tumor M... Ewing's Sarcoma... Ewing's Tumor R... Rare Diseases Sarcoma Neoplasms, Conn... Neoplasms by Hi... Neoplasms, Bone... Neoplasms, Conn... Sarcoma, Ewing Neoplasms | Vigil Irinotecan Temozolomide | 2 Years - | Gradalis, Inc. | |
| Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors | NCT02013336 | Recurrent or Re... Ewing Sarcoma Rhabdomyosarcom... Neuroblastoma Osteosarcoma | MM-398 (Irinote... | 12 Months - 20 Years | South Plains Oncology Consortium | |
| National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry | NCT04351035 | Tumors, Central... Pediatric Brain... Malignant Brain... Benign Brain Tu... | Tumour resectio... | - 18 Years | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | |
| Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma | NCT02062749 | Colorectal Canc... | Oxaliplatin | 9 Years - 21 Years | M.D. Anderson Cancer Center | |
| Pediatric Longitudinal Cohort Study of Chronic Pancreatitis | NCT03672422 | Pancreatitis, C... Pancreatitis, A... | Blood sample Patient questio... Saliva sample Urine sample | 0 Years - 17 Years | University of Iowa | |
| Erlotinib Versus Oral Etoposide in Patients With Recurrent or Refractory Pediatric Ependymoma | NCT01032070 | Recurrent or Re... | erlotinib etoposide | 1 Year - 21 Years | Astellas Pharma Inc | |
| Precision Medicine for Every Child With Cancer | NCT05504772 | Childhood Cance... Childhood Solid... Childhood Brain... Childhood Leuke... Refractory Canc... Relapsed Cancer | Whole Genome Se... RNA seq DNA Methylation Targeted Panel ... High Throughput... Patient Derived... Liquid Biopsy | 0 Years - 25 Years | Australian & New Zealand Children's Haematology/Oncology Group | |
| Mapping Psychosocial Screening to Services for Children With Cancer | NCT04132856 | Cancer | Psychosocial Na... Communication o... | 10 Years - 18 Years | The Hospital for Sick Children | |
| Exercise in Pediatric Autologous Stem Cell Transplant Patients | NCT01666015 | Cancer Autologous Hema... | EXERCISE (EX) Standard Care | 5 Years - 18 Years | University of Calgary | |
| A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors | NCT00994071 | Medulloblastoma Pontine Glioma Ependymoma Astrocytoma PNET | Temozolomide ABT-888 | - 21 Years | National Institutes of Health Clinical Center (CC) | |
| Treateament of Newly Diagnosed Acute Monocytic Leukemia in Children | NCT05313958 | Leukemia, Monoc... Pediatric AML | Cladribine G-CSF Cytarabine Idarubicin Mitoxantrone Sorafenib | 1 Month - 14 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Umbilical Cord Blood Transplant for Children With Myeloid Hematological Malignancies | NCT01247701 | Myeloid Hematol... | Busulfan Cyclophosphamid... Fludarabine Cord Blood Stem... | - 17 Years | Baylor College of Medicine | |
| EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL) | NCT01186328 | Lymphoblastic L... Lymphoblastic L... Leukemia, Lymph... Leukemia, Lymph... | EZN-3042 Cytarabine Doxorubicin Prednisone Vincristine PEG-asparaginas... Methotrexate Hydrocortisone | 1 Year - 21 Years | Therapeutic Advances in Childhood Leukemia Consortium | |
| Impact of Tumour 1q Gain in French Pediatric and Young Adult Patients With Renal Tumours | NCT04005820 | Kidney Cancer | Radiologic Cent... Tissue sample (... | - 30 Years | Assistance Publique Hopitaux De Marseille | |
| CTL019 Out of Specification MAP for ALL or DLBCL Patients | NCT03601442 | Acute Lymphobla... Diffuse Large B... | CTL019 | 1 Day - 25 Years | Novartis | |
| Heart Safety Study of Ondansetron in Children Receiving Chemotherapy | NCT01896440 | Malignant Child... | Ondansetron | 6 Months - 18 Years | University of Oklahoma | |
| Heart Safety Study of Ondansetron in Children Receiving Chemotherapy | NCT01896440 | Malignant Child... | Ondansetron | 6 Months - 18 Years | University of Oklahoma | |
| Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma | NCT02062749 | Colorectal Canc... | Oxaliplatin | 9 Years - 21 Years | M.D. Anderson Cancer Center | |
| Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients | NCT05658731 | Brain Tumor Head and Neck C... | substructure in... Neurocognitive ... MRI | 1 Year - 26 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| International Pleuropulmonary Blastoma (PPB) Treatment and Biology Registry | NCT01464606 | Pleuropulmonary... | Vincristine Dactinomycin Cyclophosphamid... Ifosfamide Doxorubicin | - 21 Years | Children's Hospitals and Clinics of Minnesota | |
| Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations | NCT03243019 | Lymphatic Malfo... Pediatric | rapamycin MRI Rapamycin dosag... | - 18 Years | University Hospital, Lille | |
| Phase I and Pharmacokinetic Trial of Paclitaxel (Taxol) Given as a 3-Hour Infusion in Pediatric Patients With Refractory Malignancy | NCT00001387 | Neoplasms | paclitaxel | - | National Institutes of Health Clinical Center (CC) | |
| Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation | NCT01316549 | Hematologic Mal... Nonmalignant Di... Immunodeficienc... Hemoglobinopath... Genetic Inborn ... Fanconi Anemia Thalassemia Sickle Cell Dis... | Fludarabine | - 17 Years | University of California, San Francisco | |
| A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis | NCT06055959 | Generalized Mya... | Zilucoplan | 12 Years - 17 Years | UCB Pharma | |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma | NCT03615404 | Glioblastoma Malignant Gliom... Medulloblastoma... Pediatric Gliob... Pediatric Brain... Pediatric Brain... | CMV-DCs with GM... Td (tetanus tox... | 0 Years - 35 Years | Duke University | |
| Home or Away From Home - Descriptive Interviews (Aim 2) | NCT02794207 | Pediatric Acute... | 8 Years - 22 Years | Children's Hospital of Philadelphia | ||
| PEG-Asparaginase Associated Pancreatitis, Hepatotoxicity and Hyperlipidemia in Children With ALL | NCT01393249 | Acute Lymphobla... Pancreatitis | 1 Year - 18 Years | Rigshospitalet, Denmark | ||
| A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas | NCT01837862 | Pilomyxoid Astr... Pilocytic Astro... Glioma, Astrocy... Optic Nerve Gli... Pleomorphic Xan... Glioblastoma Mu... Anaplastic Astr... Gliosarcoma Diffuse Intrins... DIPG Low-grade Gliom... Brainstem Gliom... | Mebendazole Vincristine Carboplatin Temozolomide Bevacizumab Irinotecan | 1 Year - 21 Years | Northwell Health | |
| Home Away From Home - Quality of Life Surveys | NCT02777021 | Pediatric Acute... | - | Children's Hospital of Philadelphia | ||
| Mucositis and Infection Reduction With Liquid Probiotics in Children With Cancer | NCT03785938 | Pediatric Cance... | Probiotic Placebo | 1 Year - 18 Years | University of Leeds | |
| Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma | NCT03117751 | Acute Lymphobla... Acute Lymphobla... | Prednisone Vincristine Daunorubicin Pegaspargase Erwinase® Cyclophosphamid... Cytarabine Mercaptopurine Dasatinib Methotrexate Blinatumomab Ruxolitinib Bortezomib Dexamethasone Doxorubicin Etoposide Clofarabine Vorinostat Idarubicin Nelarabine Thioguanine Asparaginase Er... Calaspargase Pe... | 1 Year - 18 Years | St. Jude Children's Research Hospital | |
| A Study Of Panobinostat In Children With Refractory Hematologic Malignancies | NCT01321346 | Lymphoblastic L... Myelogenous Leu... Hodgkin's Disea... Non-Hodgkin's L... | Panobinostat Cytarabine Panobinostat | 8 Years - 21 Years | Therapeutic Advances in Childhood Leukemia Consortium | |
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | NCT05106296 | Ependymoma Medulloblastoma Glioblastoma Primary Brain T... | Ibrutinib Indoximod Cyclophosphamid... Etoposide | 12 Years - 25 Years | Augusta University | |
| Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma | NCT03721068 | Neuroblastoma Osteosarcoma | iC9.GD2.CAR.IL-... Cyclophosphamid... Fludarabine | 18 Months - | UNC Lineberger Comprehensive Cancer Center | |
| A Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis | NCT03633708 | Secondary Hyper... Chronic Kidney ... | Etelcalcetide | 0 Years - 18 Years | Amgen | |
| RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies | NCT00515359 | Encephalopathy Developmental D... Cord Tumor Comp... Cord Tethering ... | Intermittent Pr... Continuous Prop... | 1 Month - 18 Years | Spectrum Health Hospitals | |
| Enteral Nutrition in Cancer Patients | NCT01304446 | Malnutrition Cancer | industrialized ... | 1 Year - | Grupo de Apoio ao Adolescente e a Crianca com Cancer | |
| PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma | NCT01393912 | Diffuse Intrins... Progressive or ... | Crenolanib | 18 Months - 21 Years | St. Jude Children's Research Hospital | |
| Constraint-Induced Movement Therapy in a Pediatric Oncology Population | NCT01447810 | Hemiplegia Brain Tumor | Focused rigidit... | 2 Years - 12 Years | St. Jude Children's Research Hospital | |
| Airway Reactivity in Children Before and After BMT Bone Marrow Transplantation | NCT00771836 | Cancer | 4 Years - 20 Years | Rambam Health Care Campus | ||
| Next Generation Pathogen Sequencing for Prediction of Adverse Events | NCT03226158 | Bloodstream Inf... | - 24 Years | St. Jude Children's Research Hospital | ||
| A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis | NCT02398994 | Myelitis, Trans... Neuromyelitis O... | Intravenous Met... Intravenous Imm... | 1 Year - | Guy's and St Thomas' NHS Foundation Trust | |
| Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia | NCT03573700 | Acute Lymphobla... Acute Lymphobla... | Cyclophosphamid... Fludarabine Mesna CliniMACS CD19- specific ... | - 21 Years | St. Jude Children's Research Hospital | |
| Haploidentical Natural Killer (NK) Cells in Patients With Relapsed or Refractory Neuroblastoma | NCT00698009 | Neuroblastoma | Fludarabine Cyclophosphamid... Natural Killer ... Mesna Interleukin-2 | - | M.D. Anderson Cancer Center | |
| Granulocyte Transfusions After Umbilical Cord Blood Transplant | NCT05425043 | Pediatric Cance... | Granulocytes | - 16 Years | University of Manchester | |
| Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GMCSF) and Isotretinoin for Consolidation of Patients With High-Risk Neuroblastoma in First Remission. | NCT04909515 | Neuroblastoma | Naxitamab GM-CSF Isotretinoin | 1 Year - | Y-mAbs Therapeutics | |
| Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients | NCT05255445 | Sickle Cell Dis... Thalassemia Pediatric Cance... | Red Blood Cell ... | - | Westat | |
| A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL | NCT01483690 | Acute Lymphobla... Precursor B-Cel... Precursor T-Cel... | Decitabine Vorinostat Vincristine Dexamethasone Mitoxantrone Pegaspargase Methotrexate | 1 Year - 21 Years | Therapeutic Advances in Childhood Leukemia Consortium | |
| Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors | NCT02015728 | Recurrent Child... | Tumor biology t... Temozolomide Etoposide Sorafenib Everolimus Erlotinib Dasatinib | 1 Month - 30 Years | Seattle Children's Hospital |
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