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Spots Global Cancer Trial Database for An Efficacy and Safety Study to Assess [18F]-ML-10 in Detecting Response of Tumors to Chemotherapy and Radiation

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Trial Identification

Brief Title: An Efficacy and Safety Study to Assess [18F]-ML-10 in Detecting Response of Tumors to Chemotherapy and Radiation

Official Title: A Prospective, Multicenter Study, to Evaluate the Efficacy and Safety of [18F]-ML-10, a Positron Emission Tomography (PET) Imaging Radiotracer, in Early Detection of Response of Non-Hematological Tumors to Concurrent Chemoradiotherapy

Study ID: NCT01260480

Study Description

Brief Summary: The purpose of this study is to determine whether \[18F\]-ML-10 used in conjunction with PET imaging is effective as an imaging tool for the early detection of response of oncological tumors in the lungs,head and neck to chemoradiation therapy. The study will evaluate the potential of \[18F\]-ML-10 used in conjunction with PET imaging to distinguish early during the course of chemoradiation therapy between a tumor that responds to the therapy, and a tumor that does not respond to the therapy. Currently, this distinction is available to the physician several weeks or months after completion of therapy, using anatomical imaging (for example Computed Tomography \[CT\] or Magnetic Resonance Imaging \[MRI\]).

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

BWH, Boston, Massachusetts, United States

Holy Name Medical Center, Teaneck, New Jersey, United States

Mount Sinai, New York, New York, United States

University of Pittsburgh, Pittsburgh,, Pennsylvania, United States

Contact Details

Name: Heron Dwight, MD

Affiliation: University of Pittsburgh Medical Center

Role: PRINCIPAL_INVESTIGATOR

Name: David Sher, MD, MPH

Affiliation: BWH, Harvard

Role: PRINCIPAL_INVESTIGATOR

Name: Aaron Allen, MD

Affiliation: Rabin Medical Center

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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