Spots Global Cancer Trial Database for Biomarker-based Study in R/M SCCHN
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Trial Identification
Brief Title: Biomarker-based Study in R/M SCCHN
Official Title: A Pilot Study of Personalized Biomarker-based Treatment Strategy or Immunotherapy in Patients With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
Study ID: NCT03088059
Study Description
Brief Summary: This is a biomarker-driven trial that will enroll patients with recurrent or metastatic squamous cell carcinoma of the head and neck progressing after first-line platinum-based chemotherapy. Based on potential biomarkers and molecular alterations identified in the biopsy from the central platform, patients will be allocated in different cohorts. There will be biomarker-positive patient cohorts and immunotherapy cohorts.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
CHU Saint-Pierre-Site Porte de Hal, Brussels, , Belgium
Cliniques Universitaires Saint-Luc, Brussel, , Belgium
Hopitaux Universitaires Bordet-Erasme - Institut Jules Bordet, Brussel, , Belgium
Grand Hopital de Charleroi - Grand Hôpital de Charleroi - Site Notre Dame, Charleroi, , Belgium
Universitair Ziekenhuis Antwerpen, Edegem, , Belgium
Universitair Ziekenhuis Gent, Gent, , Belgium
Hopital De Jolimont, Haine-Saint-Paul, , Belgium
AZ Groeninge Kortrijk - Campus Kennedylaan, Kortrijk, , Belgium
U.Z. Leuven - Campus Gasthuisberg, Leuven, , Belgium
U.Z. Leuven - Campus Gasthuisberg, Leuven, , Belgium
GasthuisZusters Antwerpen - Sint-Augustinus, Wilrijk, , Belgium
CHU Dinant Godinne - UCL Namur, Yvoir, , Belgium
CHU de Bordeaux - Groupe Hospitalier Saint-André - Hopital Saint-Andre, Bordeaux, , France
Centre Georges-Francois-Leclerc, Dijon, , France
Centre Oscar Lambret, Lille, , France
Institut de Cancerologie de l'Ouest (ICO) - Centre Rene Gauducheau, Nantes, , France
Centre Antoine Lacassagne, Nice, , France
Institut Curie, Paris, , France
Institut de Cancerologie Strasbourg Europe, Strasbourg, , France
Institut de Cancérologie de Lorraine, Vandoeuvre Les Nancy, , France
Gustave Roussy, Villejuif, , France
Azienda Ospedaliero-Universitaria Careggi, Firenze, , Italy
Azienda Ospedaliero-Universitaria Careggi, Firenze, , Italy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, , Italy
IRCCS - Fondazione G. Pascale, Napoli, , Italy
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Napoli, , Italy
ICO L'Hospitalet - Hospital Duran i Reynals (Institut Catala D'Oncologia), Barcelona, , Spain
Hospital Universitario 12 De Octubre, Madrid, , Spain
Hospital Clinico Universitario De Valencia, Valencia, , Spain
University Hospitals Birmingham NHS Foundation Trust (UHB) - UHB-Queen Elisabeth Medical Centre, Birmingham, , United Kingdom
NHS Lothian - Western General Hospital, Edinburgh, , United Kingdom
NHS Lothian - Western General Hospital, Edinburgh, , United Kingdom
NHS Greater Glasgow and Clyde - Beatson West of Scotland Cancer Centre - Gartnavel General Hospital, Glasgow, , United Kingdom
Guy's and St Thomas' NHS - Guy s and St Thomas' NHS - Guy's Hospital, London, , United Kingdom
Oxford University Hospitals NHS Trust - Churchill Hospital, Oxford, , United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust - Weston Park Hospital, Sheffield, , United Kingdom
Contact Details
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