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Spots Global Cancer Trial Database for niraparib

Every month we try and update this database with for niraparib cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
A Comparison of Platinum-based Therapy With TSR-042 and Niraparib Versus Standard of Care (SOC) Platinum-based Therapy as First-line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian CancerNCT03602859
Ovarian Neoplas...
Ovarian, Fallop...
Niraparib
Dostarlimab (TS...
Standard of car...
Dostarlimab-Pla...
Niraparib-Place...
18 Years - Tesaro, Inc.
Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate CancerNCT04592237
Aggressive Vari...
Castration-Resi...
Metastatic Pros...
Metastatic Pros...
Metastatic Pros...
Stage IV Prosta...
Cabazitaxel
Carboplatin
Cetrelimab
Niraparib
18 Years - M.D. Anderson Cancer Center
Trial Comparing Niraparib-bevacizumab-Dostarlimab and Niraparib-bevacizumab to Standard of Care in Recurrent Ovarian CancerNCT03806049
Ovarian Cancer
Niraparib
Bevacizumab
TSR042
Carboplatin
Paclitaxel
18 Years - 100 YearsNordic Society of Gynaecological Oncology - Clinical Trials Unit
A Study of ART4215 for the Treatment of Advanced or Metastatic Solid TumorsNCT04991480
Advanced Cancer
Metastatic Canc...
Breast Cancer
ART4215
Talazoparib
Niraparib
18 Years - Artios Pharma Ltd
Real-world Study of Niraparib Maintenance Treatment in Patients With Newly Diagnosed Ovarian CancerNCT04986371
Epithelial Ovar...
Niraparib
18 Years - ChineseAMS
Study of Niraparib and TSR-042 in Recurrent Endometrial CancerNCT03016338
Endometrial Can...
Niraparib
TSR-042
18 Years - University Health Network, Toronto
Study of ART6043 in Advanced/Metastatic Solid Tumors PatientsNCT05898399
Advanced Solid ...
Metastatic Soli...
ART6043
Olaparib
Niraparib
Olaparib
Niraparib
18 Years - Artios Pharma Ltd
Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube CancerNCT03586661
Deleterious BRC...
Deleterious BRC...
Endometrial Ade...
High Grade Ovar...
Platinum-Resist...
Primary Periton...
Progressive Dis...
Recurrent Endom...
Recurrent Fallo...
Recurrent Ovari...
Recurrent Prima...
Copanlisib
Niraparib
18 Years - M.D. Anderson Cancer Center
Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)NCT03869190
Urothelial Carc...
Bladder Cancer
Atezolizumab
Enfortumab Vedo...
Niraparib
Magrolimab (Hu5...
Tiragolumab
Sacituzumab Gov...
Tocilizumab
Cisplatin
Gemcitabine
18 Years - Hoffmann-La Roche
Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitorNCT05065021
Ovarian Cancer
Fallopian Tube ...
Primary Periton...
High Grade Sero...
High Grade Endo...
Niraparib
Dostarlimab
Bevacizumab
Paclitaxel
18 Years - University Health Network, Toronto
Reirradiation and Niraparib in Patients With Recurrent GlioblastomaNCT05666349
Recurrent Gliob...
Niraparib
Re-irradiation ...
18 Years - University College, London
Induction and Maintenance Treatment With PARP Inhibitor and Immunotherapy in HPV-negative HNSCCNCT04681469
Head and Neck S...
Niraparib
18 Years - Gruppo Oncologico del Nord-Ovest
Expanded Access Protocol for Niraparib in Patients With Recurrent Ovarian CancerNCT03025867
Recurrent Ovari...
Niraparib
18 Years - Tesaro, Inc.
Multi-Centre Observational Study of Maintenance Niraparib in Treatment of Ovarian CanceRNCT04295577
Ovarian Cancer
Peritoneal Canc...
Fallopian Tube ...
Niraparib
18 Years - Royal Marsden NHS Foundation Trust
Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)NCT06433219
Ovarian Cancer
Tuvusertib (M17...
Niraparib
Lartesertib (M4...
18 Years - EMD Serono
Evaluation of the Safety and Tolerability of Niraparib With Everolimus in Advanced Gynecologic Malignancies and BreastNCT03154281
Breast Cancer
Ovarian Cancer
niraparib
everolimus
18 Years - Avera McKennan Hospital & University Health Center
A Study Evaluating Safety and Efficacy of Niraparib in Patients With Previously Treated Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric AdenocarcinomaNCT03840967
Esophageal Canc...
Gastric Cancer
Adenocarcinoma
Niraparib
18 Years - Hoosier Cancer Research Network
A Study Evaluating Safety and Efficacy of Niraparib in Patients With Previously Treated Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric AdenocarcinomaNCT03840967
Esophageal Canc...
Gastric Cancer
Adenocarcinoma
Niraparib
18 Years - Hoosier Cancer Research Network
A Study of ART4215 for the Treatment of Advanced or Metastatic Solid TumorsNCT04991480
Advanced Cancer
Metastatic Canc...
Breast Cancer
ART4215
Talazoparib
Niraparib
18 Years - Artios Pharma Ltd
Study of M4344 in Combination With NiraparibNCT04655183
Advanced Solid ...
Breast Cancer
Niraparib
M4344
Niraparib
M4344
Niraparib
Niraparib
18 Years - EMD Serono
Niraparib and Selenium for the Treatment of Recurrent BRCA Negative Platinum Resistant Ovarian CancerNCT05672095
Platinum-Resist...
Platinum-Resist...
Platinum-Resist...
Recurrent Fallo...
Recurrent Ovari...
Recurrent Prima...
Biopsy
Biospecimen Col...
Niraparib
Questionnaire A...
Selenium
18 Years - City of Hope Medical Center
Combination Therapy in Cancers With Mutations in DNA Repair GenesNCT05694715
Metastatic Soli...
BRCA1 Mutation
BRCA2 Mutation
ATM Gene Mutati...
PALB2 Gene Muta...
Niraparib
Irinotecan
18 Years - University of California, San Francisco
LCI-BRE-MTN-NIR-001:Ph I Study of Niraparib in Combo With Standard Chemo in Metastatic Trip Neg Breast CancerNCT04762901
Breast Cancer
Niraparib
Doxorubicin
Cyclophosphamid...
Paclitaxel
Pegfilgrastim
Carboplatin
18 Years - Wake Forest University Health Sciences
Niraparib Versus Niraparib-bevacizumab Combination in Women With Platinum-sensitive Epithelial Ovarian CancerNCT02354131
Ovarian Cancer
Niraparib
Bevacizumab
18 Years - Nordic Society of Gynaecological Oncology - Clinical Trials Unit
Real-world Study of Niraparib Maintenance Treatment in Patients With Newly Diagnosed Ovarian CancerNCT04986371
Epithelial Ovar...
Niraparib
18 Years - ChineseAMS
European Trial on Enhanced DNA Repair Inhibition in Ovarian CancerNCT03783949
Ovarian Cancer
Fallopian Tube ...
Primary Periton...
Ganetespib
Niraparib
Carboplatin
Paclitaxel
Gemcitabine
18 Years - Universitaire Ziekenhuizen KU Leuven
Efficacy and Adverse Effects of Niraparib in Ovarian Cancer.NCT05583799
Ovarian Cancer
18 Years - First Affiliated Hospital Xi'an Jiaotong University
A Dose-escalation Study of the Safety and Pharmacology of DAN-222 in Subjects With Metastatic Breast CancerNCT05261269
HER2-negative M...
DAN-222
Niraparib
18 Years - Dantari, Inc.
Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast CancerNCT04837209
Breast Cancer
Triple Negative...
Niraparib
Dostarlimab
Radiation thera...
18 Years - Massachusetts General Hospital
European Trial on Enhanced DNA Repair Inhibition in Ovarian CancerNCT03783949
Ovarian Cancer
Fallopian Tube ...
Primary Periton...
Ganetespib
Niraparib
Carboplatin
Paclitaxel
Gemcitabine
18 Years - Universitaire Ziekenhuizen KU Leuven
ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian CancerNCT04267939
Advanced Solid ...
Ovarian Cancer
Elimusertib (BA...
Niraparib
18 Years - Bayer
Biomarker-based Study in R/M SCCHNNCT03088059
Carcinoma, Squa...
Afatinib
Palbociclib
standard of car...
IPH2201
Durvalumab
Niraparib
INCAGN01876
18 Years - European Organisation for Research and Treatment of Cancer - EORTC
A Real-World Patient-Reported Outcomes Study in Patients With Long-Term Use of NiraparibNCT06037213
Ovarian Cancer
18 Years - Peking Union Medical College Hospital
LCI-BRE-MTN-NIR-001:Ph I Study of Niraparib in Combo With Standard Chemo in Metastatic Trip Neg Breast CancerNCT04762901
Breast Cancer
Niraparib
Doxorubicin
Cyclophosphamid...
Paclitaxel
Pegfilgrastim
Carboplatin
18 Years - Wake Forest University Health Sciences
A Study of Niraparib in Patients With Ovarian Cancer in Clinical PracticeNCT05021562
Ovarian Cancer
Niraparib
- Takeda
PARP Inhibitor Oral Maintenance in Low-Risk Ovarian CancerNCT05187208
Epithelial Ovar...
Ovarian Cancer
Ovarian Cancer ...
Ovarian Cancer ...
Niraparib
20 Years - Seoul National University Hospital
Niraparib Plus Aromatase Inhibitors for Luminal-like(HER2-,ER+) and gBRCA or HDR+ Metastatic Breast Cancer (LUZERN)NCT04240106
Breast Cancer
Breast Cancer M...
Niraparib
Aromatase Inhib...
18 Years - MedSIR
Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast CancerNCT05601440
Breast Cancer
RP-6306
Gemcitabine
Observation
Niraparib
Fulvestrant
- Canadian Cancer Trials Group
Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian CancerNCT02657889
Neoplasms
Triple Negative...
Ovarian Cancer
Breast Cancer
Metastatic Brea...
Advanced Breast...
Stage IV Breast...
Fallopian Tube ...
Peritoneal Canc...
niraparib
pembrolizumab
18 Years - Tesaro, Inc.
Niraparib + Ipilimumab or Nivolumab in Progression Free Pancreatic Adenocarcinoma After Platinum-Based ChemotherapyNCT03404960
Pancreatic Aden...
Niraparib + Niv...
Niraparib + Ipi...
18 Years - University of Pennsylvania
Niraparib Maintenance Treatment in mCRC With a Partial o Complete Response After Oxaliplatin-based Induction TherapyNCT05412706
Metastatic Colo...
Niraparib
18 Years - Ospedale Policlinico San Martino
Study to Evaluate the Safety and Efficacy of TSR-042, Bevacizumab, and Niraparib in Participants With Recurrent Ovarian CancerNCT05751629
Ovarian Neoplas...
Dostarlimab
Bevacizumab
Niraparib
18 Years - Tesaro, Inc.
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent GliomaNCT05076513
Glioblastoma
Glioblastoma Mu...
Glioma
GBM
Glioma, Maligna...
Glioblastoma Mu...
Niraparib
Radiation thera...
18 Years - St. Joseph's Hospital and Medical Center, Phoenix
Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal CancerNCT04673448
Anatomic Stage ...
Anatomic Stage ...
BRCA-Associated...
BRCA-Associated...
Metastatic BRCA...
Metastatic Brea...
Metastatic Fall...
Metastatic Mali...
Metastatic Ovar...
Metastatic Panc...
Metastatic Prim...
Prognostic Stag...
Prognostic Stag...
Stage III Fallo...
Stage III Ovari...
Stage III Pancr...
Stage III Prima...
Stage IV Fallop...
Stage IV Ovaria...
Stage IV Pancre...
Stage IV Primar...
Unresectable Br...
Unresectable Fa...
Unresectable Ma...
Unresectable Ov...
Unresectable Pa...
Unresectable Pr...
Dostarlimab
Niraparib
18 Years - University of Washington
Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic CancerNCT04493060
Metastatic Panc...
Stage IV Pancre...
Dostarlimab
Niraparib
18 Years - Mayo Clinic
Study of the Combination Dostarlimab With Niraparib In Patients With Penile CarcinomaNCT05526989
Penile Carcinom...
Dostarlimab
Niraparib
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Maintenance Niraparib and Dostarlimab in Advanced CholangiocarcinomaNCT04895046
HRD
Cholangiocarcin...
Metastatic Canc...
Niraparib
Dostarlimab
Dostarlimab
18 Years - Hoosier Cancer Research Network
A Study of Niraparib in Patients With Ovarian Cancer Who Have Received Three or Four Previous Chemotherapy RegimensNCT02354586
Ovarian Neoplas...
Ovarian Cancer
Niraparib
18 Years - Tesaro, Inc.
A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate CancerNCT06320067
Prostate Cancer...
Stereotactic Ab...
177Lu-PSMA-617
Niraparib and A...
Abiraterone Ace...
Apalutamide
Androgen Depriv...
Androgen Recept...
Local Radiother...
Prednisolone
Docetaxel
18 Years - University College, London
Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast CancerNCT03368729
Metastatic Brea...
HER2 Positive B...
Niraparib
Trastuzumab
18 Years - University of Alabama at Birmingham
An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair AnomaliesNCT02854436
Prostatic Neopl...
Niraparib
18 Years - Janssen Research & Development, LLC
A Phase III Trial of Niraparib Versus Physician's Choice in HER2 Negative, Germline BRCA Mutation-positive Breast Cancer PatientsNCT01905592
Neoplasms, Brea...
Carcinoma of Br...
Human Epidermal...
BRCA1 Gene Muta...
BRCA2 Gene Muta...
Ovarian Neoplas...
niraparib
Physician's cho...
18 Years - Tesaro, Inc.
Niraparib Efficacy in Patient With Unresectable MesotheliomaNCT05455424
Mesothelioma, M...
Niraparib Oral ...
Active Symptom ...
18 Years - University Hospital Southampton NHS Foundation Trust
Personalized Medicine for Advanced Biliary Cancer PatientsNCT05615818
Biliary Tract N...
Futibatinib
Ivosidenib
Zanidatamab
Trastuzumab
Neratinib
Encorafenib
Binimetinib
Niraparib
Cisplatin
Gemcitabine
18 Years - UNICANCER
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate CancerNCT03748641
Castration-Resi...
Niraparib
Abiraterone Ace...
Prednisone
Placebo
New Formulation...
18 Years - Janssen Research & Development, LLC
Niraparib in Combination With Osimertinib in EGFR-Mutated Advanced Lung CancerNCT03891615
Lung Cancer
Niraparib
Osimertinib
18 Years - Massachusetts General Hospital
LCI-BRE-MTN-NIR-001:Ph I Study of Niraparib in Combo With Standard Chemo in Metastatic Trip Neg Breast CancerNCT04762901
Breast Cancer
Niraparib
Doxorubicin
Cyclophosphamid...
Paclitaxel
Pegfilgrastim
Carboplatin
18 Years - Wake Forest University Health Sciences
ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing SarcomaNCT02044120
Ewing Sarcoma
niraparib
Temozolomide
Irinotecan
13 Years - Sarcoma Alliance for Research through Collaboration
A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Anticancer Activity of GSK4524101 Alone or With Niraparib in Participants With Solid TumorsNCT06077877
Neoplasms
GSK4524101
Niraparib
18 Years - GlaxoSmithKline
Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)NCT05700721
Brain Metastase...
Niraparib
Dostarlimab
18 Years - M.D. Anderson Cancer Center
Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response DefectsNCT04030559
ATM Gene Mutati...
BRCA1 Gene Muta...
BRCA2 Gene Muta...
BRIP1 Gene Muta...
CDK12 Gene Muta...
CHEK1 Gene Muta...
CHEK2 Gene Muta...
DNA Damage Resp...
DNA Repair Gene...
FANCA Gene Muta...
FANCD2 Gene Mut...
FANCL Gene Muta...
GEN1 Gene Mutat...
NBN Gene Mutati...
Prostate Carcin...
RAD51 Gene Muta...
RAD51C Gene Mut...
Niraparib
Niraparib Tosyl...
Radical Prostat...
18 Years - University of California, Davis
A Chinese Patent Medicine Yangzhengxiaoji Capsule to Improve the Nausea of Niraparib in the Maintenance Treatment in Ovarian CancerNCT05641506
Ovarian Cancer
Yangzheng Xiaoj...
Niraparib
18 Years - Sichuan Cancer Hospital and Research Institute
Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate CancerNCT04947254
Prostate Carcin...
Stage IIC Prost...
Stage III Prost...
Stage IIIA Pros...
Stage IIIB Pros...
Stage IIIC Pros...
Stage IVA Prost...
Abiraterone Ace...
Antiandrogen Th...
Apalutamide
Biopsy
Niraparib
Prednisone
Radiation Thera...
18 Years - M.D. Anderson Cancer Center
Niraparib Plus Aromatase Inhibitors for Luminal-like(HER2-,ER+) and gBRCA or HDR+ Metastatic Breast Cancer (LUZERN)NCT04240106
Breast Cancer
Breast Cancer M...
Niraparib
Aromatase Inhib...
18 Years - MedSIR
Niraparib With beVAcizumab After Complete cytoreductioN in Patients With ovArian CancerNCT05183984
Ovarian Cancer
Chemotherapy
Bevacizumab-Aww...
Niraparib
18 Years - 99 YearsARCAGY/ GINECO GROUP
Niraparib as First Line Therapy With Metastatic Homologous Repair-deficient Pancreatic CancerNCT05442749
Metastatic Panc...
Niraparib
18 Years - Centre Leon Berard
Study to Evaluate the Safety and Efficacy of TSR-042, Bevacizumab, and Niraparib in Participants With Recurrent Ovarian CancerNCT05751629
Ovarian Neoplas...
Dostarlimab
Bevacizumab
Niraparib
18 Years - Tesaro, Inc.
Enzalutamide and Niraparib in the Treatment of Metastatic Castrate-Resistant Prostate Cancer (CRPC)NCT02500901
Metastatic Pros...
Enzalutamide
Niraparib
18 Years - Hoosier Cancer Research Network
A Study of ZN-c3 and Niraparib in Subjects With Platinum-Resistant Ovarian CancerNCT05198804
Ovarian Cancer
Platinum-resist...
Primary Periton...
Fallopian Tube ...
ZN-c3
Niraparib
18 Years - K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Genome-Based Assessment of Niraparib (ZEJULA®) Efficacy in Advanced Solid TumorS With Homologous Recombination DeficiencyNCT06237205
Efficacy
Niraparib
19 Years - Korea University Anam Hospital
A Dose-escalation Study of the Safety and Pharmacology of DAN-222 in Subjects With Metastatic Breast CancerNCT05261269
HER2-negative M...
DAN-222
Niraparib
18 Years - Dantari, Inc.
Study to Evaluate the Efficacy and Safety of the Combination of Niraparib and Dostarlimab (TSR-042) in Participants With Platinum Resistant Ovarian CancerNCT03955471
Ovarian Neoplas...
Niraparib
Dostarlimab
18 Years - Tesaro, Inc.
Niraparib as Maintenance Therapy in Patients With Platinum Sensitive Recurrent Ovarian CancerNCT04546373
Epithelial Ovar...
Fallopian Tube ...
Primary Periton...
Niraparib
18 Years - Grupo Español de Investigación en Cáncer de Ovario
Niraparib Maintenance in HRD-Positive Advanced Ovarian Cancer Following Front-Line Chemotherapy + BevacizumabNCT06141265
Ovarian, Fallop...
Niraparib
18 Years - 75 YearsPeking University Cancer Hospital & Institute
Combination Niraparib and Dostarlimab Therapy for Recurrent or Persistent Uterine Serous CarcinomaNCT05870761
Recurrent Endom...
Biospecimen Col...
Computed Tomogr...
Dostarlimab
Magnetic Resona...
Niraparib
18 Years - Ohio State University Comprehensive Cancer Center
Safety and Efficacy of AsiDNATM, a DNA Repair Inhibitor, Administered Intravenously in Addition to PARP Inhibitors in Patients With Relapsed Platinum Sensitive Ovarian Cancer Already Treated With PARP Inhibitors Since at Least 6 MonthsNCT04826198
Ovarian Cancer
AsiDNA
Niraparib
Olaparib
Rucaparib
18 Years - Gustave Roussy, Cancer Campus, Grand Paris
Study Evaluating the Efficacy of Niraparib and Dostarlimab (TSR-042) in Recurrent/Metastatic HNSCCNCT04313504
Head and Neck C...
Niraparib
Dostarlimab
18 Years - University of Cincinnati
A Study of Niraparib in Combination With Brivanib in Recurrent Ovarian CancerNCT03895788
Ovarian Cancer
niraparib
Brivanib
18 Years - Hunan Cancer Hospital
A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate CancerNCT06320067
Prostate Cancer...
Stereotactic Ab...
177Lu-PSMA-617
Niraparib and A...
Abiraterone Ace...
Apalutamide
Androgen Depriv...
Androgen Recept...
Local Radiother...
Prednisolone
Docetaxel
18 Years - University College, London
A Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.NCT05335993
Recurrent Ovari...
Recurrent Epith...
Recurrent Epith...
Recurrent Fallo...
Peritoneal Canc...
Recurrent Carci...
Adenocarcinoma ...
Oregovomab
Niraparib
18 Years - 99 YearsCanariaBio Inc.
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