Spots Global Cancer Trial Database for Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing

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Trial Identification

Brief Title: Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing

Official Title: Genetic Variations,Immuno-sequencing and Circulating Tumor DNA(ctDNA) for Early Diagnosis of Small Pulmonary Nodules

Study ID: NCT03320044

Conditions

Carcinoma

Non-small-cell Lung Cancer

Lung Neoplasm

Interventions

Study Description

Brief Summary: Analyse immune repertoire and genetic mutations of benign and malignant pulmonary nodule，and evaluate peripheral blood detection for identifying nature of pulmonary nodule.

Detailed Description: Early diagnosis of lung cancer is of vital importance in lung cancer treatment. This research will first analyse the features of immune repertoire and genetic mutations from tissue of benign and malignant pulmonary nodule，then explore the feasibility of detecting these features from peripheral blood sample, and finally evaluate peripheral blood detection of lung cancer related immune repertoire and genetic mutations for identifying nature of pulmonary nodule.