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Brief Title: Efficacy and Safety of Anlotinib as Maintenance Treatment After First-line Chemotherapy in SCLC
Official Title: Efficacy and Safety of Anlotinib as Maintenance Treatment After First-line Chemotherapy in Small Cell Lung Cancer(SCLC):a Phase II Study
Study ID: NCT03780283
Brief Summary: Investigations prospectively collected the SCLC patients who received current standard first-line treatment, the response was not progression disease(PD). and then participants receive Anlotinib 12mg, administered as PO on Day1-14 of each 21-day cycle until documented PD or had unacceptable toxicity. This regimen is compared to the effects a observation without treatment after the first-line therapy. The aim of the study is therefore to evaluate the efficacy and safety of Anlotinib as maintenance treatment after first-line chemotherapy in SCLC patients.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The First Hospital of Shijiazhuang, Shijiazhuang, Hebei, China
Name: Yan Zhang, M.D.
Affiliation: The First Hospital of Shijiazhuang
Role: STUDY_CHAIR