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Spots Global Cancer Trial Database for Urinary Circulating Tumor DNA Detection in Non-small Cell Lung Cancer: a Prospective Study

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Urinary Circulating Tumor DNA Detection in Non-small Cell Lung Cancer: a Prospective Study

Official Title: Urinary Circulating Tumor DNA Detection in Non-small Cell Lung Cancer: a Prospective Study

Study ID: NCT02907606

Interventions

Study Description

Brief Summary: This study will evaluate the feasibility and effectiveness of urinary ctDNA detection and dynamic monitoring during treatment of NSCLC patients prospectively,by collecting and detecting tumor tissues, peripheral blood samples and urine samples of NSCLC patients.

Detailed Description: Liquid biopsy, specifically through the assessment of circulating tumor DNA(ctDNA) from peripheral blood, has shown great promise in lung cancer diagnosis and therapeutic monitoring. Urinary samples are completely non-invasive and easily obtainable compared to blood and tissue extraction. To date, only a limited number of published studies have examined the feasibility of ctDNA detection from urine. This study will collect tumor tissues, pretreatment peripheral blood samples and urine samples from different TNM stages of NSCLC patients, and detect EGFR gene mutations in paired samples.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Peking University People'S Hospital, Beijing, Beijing, China

Contact Details

Name: Xiao Li, M.D

Affiliation: Peking University People's Hospital

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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