Spots Global Cancer Trial Database for Treatment of Cerebral Radiation Necrosis (CRN) With Nerve Growth Factor (NGF)
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Trial Identification
Brief Title: Treatment of Cerebral Radiation Necrosis (CRN) With Nerve Growth Factor (NGF)
Official Title:
Study ID: NCT02032147
Interventions
Study Description
Brief Summary: Cerebral radiation necrosis (CRN) is a well-documented late complication of radiation therapy for cancers, and may have a devastating effect on the patient's quality of life (QOL). However,CRN was once regarded as a progressive and irreversible disease, no standard therapy has been suggested for CRN. In our clinical practice, we have used nerve growth factor(NGF) to treat CRN, and found that GM1 can successfully reverse CRN. A case report has been published in Journal of Clinical Oncology (JCO) in 2011. So we carried out this prospective study to test the efficacy of NGF for CRN.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Shanghai Cancer Center, Fudan University, Shanghai, Shanghai, China
Contact Details
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