Spots Global Cancer Trial Database for HPV DNA Self-sampling in a General Practitioner's Office.

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Trial Identification

Brief Title: HPV DNA Self-sampling in a General Practitioner's Office.

Official Title: Benefit of Self-sampling for HPV DNA in a General Practitioner's Office to Improve Participation in Cervical Screening - The ASTRA Study.

Study ID: NCT06253169

Conditions

Cervical Cancer

HPV Infection

Precancerous Lesion

Interventions

HPV DNA self-test

Study Description

Brief Summary: One of the limitations of organized cervical screening in the Czech Republic is the lack of participation in preventive gynecological examinations. The aim of the project is to evaluate the benefits of self-sampling for HPV DNA in general practitioners' outpatient clinics to improve population participation in cervical screening.

Detailed Description: Organized cervical screening in the Czech Republic has a long-term participation rate of about 56% of the target population. Despite active invitations through health insurance companies, a part of the population is resistant and does not participate in screening visits to gynaecologists in the long term. A significant proportion of such women, however, regularly visit their general practitioner due to other comorbidities. The aim of the ASTRA project is to assess whether an effective way to increase the proportion of women attending cervical screening is to perform self-testing for HPV DNA in the GP's office.