Spots Global Cancer Trial Database for Cytogenetic Study of Ocular Melanoma
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Trial Identification
Brief Title: Cytogenetic Study of Ocular Melanoma
Official Title: Molecular and Cytogenetic Studies of Ocular Melanoma
Study ID: NCT00344799
Conditions
Interventions
Study Description
Brief Summary: Patients who are diagnosed with choroidal melanoma and undergo I-125 plaque or enucleation surgery consent to participate in the study. A tumor sample taken during surgery is studied in the lab for genetic features. These features and features of subjects' clinical course are recorded. Analysis of the data may identify genetic features that are indicative of prognostic factors including risk of metastasis.
Detailed Description: The Jules Stein Eye Institute Ocular Melanoma Research Group is conducting cytogenetic studies of choroidal melanoma to improve the screening of biopsy samples of choroidal melanoma through cytogenetic analysis. Our goal is to identify molecular probes that specifically target regions of chromosomes that undergo changes characteristic of metastatic choroidal melanoma.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Jules Stein Eye Institute, Los Angeles, California, United States
Contact Details
Name: Tara M McCannel, MD, PhD
Affiliation: Jules Stein Eye Institute, UCLA
Role: PRINCIPAL_INVESTIGATOR
Name: Bradley R Straatsma, MD, JD
Affiliation: Jules Stein Eye Institute, UCLA
Role: STUDY_DIRECTOR
Name: Lynn Gordon, MD, PhD
Affiliation: Jules Stein Eye Institute, UCLA
Role: STUDY_CHAIR
Name: Ben Glasgow, MD
Affiliation: Jules Stein Eye Institute, UCLA
Role: STUDY_CHAIR
Name: Nagesh P Rao, PhD
Affiliation: UCLA Pathology and Laboratory Medicine
Role: STUDY_CHAIR
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