Spots Global Cancer Trial Database for Effectiveness of Garlic Oil in the Treatment of Arsenical Palmer Keratosis
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Trial Identification
Brief Title: Effectiveness of Garlic Oil in the Treatment of Arsenical Palmer Keratosis
Official Title: Effectiveness of Garlic Oil in the Treatment of Arsenical Palmer Keratosis
Study ID: NCT01748669
Conditions
Interventions
Study Description
Brief Summary: Twenty patients of mild to moderate degree of arsenical palmer keratosis will be treated with garlic oil capsule orally for 12 weeks to examine its effectiveness in reducing body arsenic load and clinical symptoms. Similar treatment with similar number of arsenic exposed controls and healthy volunteers will be included for comparison.
Detailed Description: Thousands of Bangladeshi are suffering from arsenic-induced keratosis affecting palms and soles. Palmer keratosis, particularly in young female, affects the socioeconomic condition. Till today there is no effective treatment. Twenty patients of mild to moderate degree of arsenical palmer keratosis will be treated with garlic oil in soft capsule (10 mg/day) orally for 12 weeks. Similar treatment will be given to 20 arsenic exposed controls and 20 healthy volunteers for comparison. The aim of this study is to examine the effectiveness of oral administration of garlic oil to reduce body arsenic load and clinical symptoms of arsenical palmer keratosis.
Eligibility
Minimum Age: 20 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Bangabandhu Sheikh Mujib Medical University, Dhaka, , Bangladesh
Contact Details
Name: Mir Misbahuddin, MBBS, PhD
Affiliation: Department of Pharmacology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Role: PRINCIPAL_INVESTIGATOR
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