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Spots Global Cancer Trial Database for A Study of Imatinib and Valproic Acid in Patients With Chronic Myelogenous Leukemia (CML)

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: A Study of Imatinib and Valproic Acid in Patients With Chronic Myelogenous Leukemia (CML)

Official Title: A Phase II Study of Imatinib and Valproic Acid in Patients With CML

Study ID: NCT01011998

Study Description

Brief Summary: The aim of this study is to test the effect of the combination of valproate in combination with imatinib with an aim of achieving a maximal molecular response as the primary goal.

Detailed Description: The aim of this study is to test the effect of the combination of valproate in combination with imatinib with an aim of achieving a maximal molecular response as the primary goal. Briefly, patients with CML who are taking imatinib and have been found to have a plateau in their level of the bcr-abl transcript will be eligible to participate in the study. Valproate will then be added to the imatinib, and subsequent bcr-abl transcripts will be monitored to see if the addition of valproate produced a further reduction. Patients will be monitored for efficacy and toxicity.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

Contact Details

Name: Ian Rabinowitz, MD

Affiliation: University of New Mexico Cancer Center

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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