Spots Global Cancer Trial Database for valproic acid
Every month we try and update this database with for valproic acid cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors | NCT00302159 | High Grade Glio... Brain Tumors | adjuvant therap... Temozolomide Valproic Acid Radiation thera... | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | |
| Preoperative Valproic Acid and Radiation Therapy for Rectal Cancer | NCT01898104 | Colorectal Canc... | preoperative ra... Valproic Acid Capecitabine | 18 Years - 70 Years | National Cancer Institute, Naples | |
| Valproic Acid in Treating Patients With Progressive, Non-Metastatic Prostate Cancer | NCT00670046 | Prostate Cancer | valproic acid standard of car... | 18 Years - 85 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Azacitidine and Valproic Acid Plus Carboplatin in Patients With Ovarian Cancer | NCT00529022 | Solid Tumors | Azacitidine Valproic Acid Carboplatin | - | M.D. Anderson Cancer Center | |
| Decitabine and Valproic Acid in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma | NCT00079378 | Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Recurrent Adult... Recurrent Small... Refractory Chro... Untreated Adult... | decitabine valproic acid pharmacological... laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Decitabine and Valproic Acid in Treating Patients With Non-Small Cell Lung Cancer | NCT00084981 | Recurrent Non-s... Stage IV Non-sm... | decitabine valproic acid pharmacological... laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Valproic Acid Plus Cisplatin and Cetuximab in Recurrent and/or Metastatic Squamous Cell Carcinoma of Head and Neck | NCT02624128 | Squamous Cell C... | Valproic Acid Cisplatin Cetuximab | 18 Years - | National Cancer Institute, Naples | |
| Avelumab With Valproic Acid in Virus-associated Cancer | NCT03357757 | Cancer That is ... p16 Positive SC... Squamous Cell C... p16 Positive Sq... p16 Positive Sq... p16 Positive Sq... EBER Positive N... EBER Positive H... | Valproic Acid Avelumab | 18 Years - | AHS Cancer Control Alberta | |
| Phase I/II Trial of Valproic Acid and Karenitecin for Melanoma | NCT00358319 | Malignant Melan... | Karenitecin Valproic Acid | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas | NCT01106872 | Sarcoma Soft Tissue Sar... Locally Advance... Unresectable Sa... Metastatic Sarc... | Bevacizumab, Ge... | 18 Years - 99 Years | University of Iowa | |
| Azacytidine and Valproic Acid in Patients With Advanced Cancers | NCT00496444 | Advanced Cancer... | Azacitidine Valproic Acid | 2 Years - | M.D. Anderson Cancer Center | |
| VPA Expanded UCB Transplantation for Treatment of Patients With Hematological Malignancies | NCT03885947 | Hematological M... Acute Leukemia ... Acute Lymphobla... Myelodysplastic... Non-Hodgkin Lym... Hodgkin Lymphom... | Cord blood stem... Valproic Acid Fludarabine cytoxan Thiotepa TBI | 18 Years - 65 Years | Icahn School of Medicine at Mount Sinai | |
| Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of Recurrence | NCT02446431 | Solid Tumor | Bevacizumab Cyclophosphamid... Valproic Acid Temsirolimus | 12 Months - 31 Years | Miller Children's & Women's Hospital Long Beach | |
| Seizure Treatment in Glioma | NCT03048084 | Glioma | Levetiracetam Valproic Acid | 18 Years - | Leiden University Medical Center | |
| Phase I Trial of Valproic Acid and Epirubicin in Solid Tumor Malignancies | NCT00246103 | Neoplasms, Adva... | Valproic acid Epirubicin 5-fluorouracil Cyclophosphamid... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| A Phase II Trial of Valproic Acid in Patients With Advanced Thyroid Cancers of Follicular Cell Origin | NCT01182285 | Thyroid Neoplas... | Valproic Acid Liothyronine So... | 18 Years - 100 Years | National Institutes of Health Clinical Center (CC) | |
| Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma | NCT02761291 | Nasopharyngeal ... | Gemcitabine Valproic acid Valganciclovir | 20 Years - 80 Years | Chang Gung Memorial Hospital | |
| Folate Receptor in Diagnosing Ovarian Cancer Using Serum Samples From Patients With Newly Diagnosed Pelvic Mass or Previously Diagnosed Ovarian Cancer | NCT02520115 | Adnexal Mass Borderline Ovar... Ovarian Clear C... Ovarian Endomet... Ovarian Neoplas... Ovarian Serous ... Recurrent Ovari... | Dexamethasone Laboratory Biom... Valproic Acid | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| Valproic Acid (Depakote ER) in Patients With Advanced Thyroid Cancer | NCT00525135 | Head and Neck C... | Valproic Acid | 18 Years - | University of California, San Francisco | |
| Valproic Acid/Simvastatin Plus Gemcitabine/Nab-paclitaxel Based Regimens in Untreated Metastatic Pancreatic Adenocarcinoma Patients | NCT05821556 | Adenocarcinoma ... | Valproic acid Simvastatin 20m... Gemcitabine 100... Nab paclitaxel Cisplatin Capecitabine | 18 Years - | National Cancer Institute, Naples | |
| Valproic Acid (Depakote ER) in Patients With Advanced Thyroid Cancer | NCT00525135 | Head and Neck C... | Valproic Acid | 18 Years - | University of California, San Francisco | |
| Valproic Acid With Chemoradiotherapy for Non-Small-Cell Lung Cancer | NCT01203735 | Locally Advance... | Valproic acid | 18 Years - 75 Years | Soroka University Medical Center | |
| Valproic Acid and Platinum-based Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma | NCT01695122 | Head and Neck C... Oral Cavity Can... Oropharyngeal C... | Valproic Acid | - 65 Years | Instituto do Cancer do Estado de São Paulo | |
| Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL) | NCT00810680 | Chronic Lymphoc... | Valproic acid | 18 Years - | All India Institute of Medical Sciences, New Delhi | |
| Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) | NCT00414310 | Myelodysplastic... Acute Myelogeno... | Decitabine Valproic Acid | - | M.D. Anderson Cancer Center | |
| Differentiation Induction in Acute Myelogenous Leukemia | NCT00175812 | Acute Myelogeno... | all-trans retin... Valproic acid Theophyllin | 18 Years - | University of Bergen | |
| Valproic Acid in Treating Patients With Progressive, Non-Metastatic Prostate Cancer | NCT00670046 | Prostate Cancer | valproic acid standard of car... | 18 Years - 85 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Phase II 5-Azacytidine Plus VPA Plus ATRA | NCT00326170 | Myelodysplastic... Acute Myelogeno... | 5-Azacytidine (... Valproic Acid All-Trans Retin... | 3 Years - | M.D. Anderson Cancer Center | |
| Study of Valproic Acid (VPA) vs Placebo to Shorten Time of Indwelling Pleural Catheter | NCT01900730 | Breast Cancer | Placebo Valproic Acid (... Questionnaires Pill Diary Drainage Diary | 18 Years - | M.D. Anderson Cancer Center | |
| Adjuvant Valproate for High Grade Sarcomas | NCT01010958 | High Grade Sarc... | Valproic Acid | 18 Years - | Columbia University | |
| Azacytidine and Valproic Acid in Patients With Advanced Cancers | NCT00496444 | Advanced Cancer... | Azacitidine Valproic Acid | 2 Years - | M.D. Anderson Cancer Center | |
| International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) | NCT03243461 | Glioblastoma WH... Diffuse Midline... Anaplastic Astr... Diffuse Intrins... Gliomatosis Cer... | Temozolomide + ... | 3 Years - 17 Years | University of Göttingen | |
| Valproic Acid and Bevacizumab in Patients With Advanced Cancer | NCT00530907 | Advanced Cancer | Valproic Acid Bevacizumab | - | M.D. Anderson Cancer Center | |
| Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas | NCT01106872 | Sarcoma Soft Tissue Sar... Locally Advance... Unresectable Sa... Metastatic Sarc... | Bevacizumab, Ge... | 18 Years - 99 Years | University of Iowa | |
| Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma | NCT00879437 | Glial Cell Tumo... Malignant Gliom... Glioblastoma Mu... Anaplastic Astr... Gliomatosis Cer... Gliosarcoma Brainstem Gliom... Diffuse Intrins... | Valproic acid Bevacizumab Radiation thera... | 3 Years - 21 Years | Baylor College of Medicine | |
| Valproic Acid With Chemoradiotherapy for Pancreatic Cancer | NCT01333631 | Pancreatic Canc... | Valproic acid | 18 Years - 75 Years | Soroka University Medical Center | |
| Valproic Acid in Combination With Bevacizumab and Oxaliplatin/Fluoropyrimidine Regimens in Patients With Ras-mutated Metastatic Colorectal Cancer | NCT04310176 | Ras-mutated Met... | Bevacizumab mFOLFOX6 regime... mOXXEL regimen Valproic acid Capecitabine 5-fluorouracil | 18 Years - | National Cancer Institute, Naples | |
| Efficacy and Tolerability of the Combination of Valproic Acid and Lenalidomide in the Treatment of Patients With Myelodysplastic Syndrome | NCT00977132 | Myelodysplastic... | Valproic aicd Lenalidomide | 18 Years - | Heinrich-Heine University, Duesseldorf | |
| Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic Acid | NCT02608736 | Head and Neck S... | Valproic Acid Placebo | 18 Years - | Barretos Cancer Hospital | |
| A Study of Imatinib and Valproic Acid in Patients With Chronic Myelogenous Leukemia (CML) | NCT01011998 | Chronic Myeloge... | Gleevec (imatin... | 18 Years - | New Mexico Cancer Care Alliance | |
| Impact of Valproate on Angiogenesis and Histone Deacetylation in Bladder Cancer | NCT01738815 | Hematuria Bladder Cancer | Valproic Acid | 21 Years - | State University of New York - Upstate Medical University | |
| Disease Stabilization in AML by Treatment With ATRA, Valproic Acid and Low-dose Cytarabine | NCT00995332 | Acute Myelogeno... | Cytarabine, all... | 18 Years - | University of Bergen | |
| Valproic Acid-Based 2-Agent Oral Regimens for Patients With Advanced Solid Tumor | NCT00495872 | Solid Tumors | Dasatinib Erlotinib Lapatinib Lenalidomide Sorafenib Sunitinib Valproic Acid | - | M.D. Anderson Cancer Center | |
| PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS | NCT00439673 | Myelodysplastic... | 5-Azacytidine Valproic Acid ATRA | 18 Years - | Gruppo Italiano Malattie EMatologiche dell'Adulto | |
| Decitabine and Valproic Acid in Treating Patients With Non-Small Cell Lung Cancer | NCT00084981 | Recurrent Non-s... Stage IV Non-sm... | decitabine valproic acid pharmacological... laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic Acid | NCT02608736 | Head and Neck S... | Valproic Acid Placebo | 18 Years - | Barretos Cancer Hospital | |
| Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL) | NCT00810680 | Chronic Lymphoc... | Valproic acid | 18 Years - | All India Institute of Medical Sciences, New Delhi | |
| Valproate and Etoposide for Patients With Neuronal Tumors and Brain Metastases | NCT00513162 | Neuroectodermal... Brain Metastase... Advanced Cancer | Valproate Etoposide | - | M.D. Anderson Cancer Center | |
| Avelumab With Valproic Acid in Virus-associated Cancer | NCT03357757 | Cancer That is ... p16 Positive SC... Squamous Cell C... p16 Positive Sq... p16 Positive Sq... p16 Positive Sq... EBER Positive N... EBER Positive H... | Valproic Acid Avelumab | 18 Years - | AHS Cancer Control Alberta | |
| Azacytidine With Valproic Acid Versus Ara-C in Acute Myeloid Leukemia (AML)/ Myelodysplastic Syndrome (MDS) Patients | NCT00382590 | Acute Myelogeno... Myelodysplastic... Leukemia | 5-Azacytidine Ara-C Valproic Acid (... | 60 Years - | M.D. Anderson Cancer Center | |
| Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma | NCT01817751 | Glioblastoma Recurrent Adult... Malignant Gliom... WHO Grade III G... | sorafenib tosyl... valproic acid sildenafil citr... | 18 Years - | Virginia Commonwealth University | |
| Valproic Acid-Based 2-Agent Oral Regimens for Patients With Advanced Solid Tumor | NCT00495872 | Solid Tumors | Dasatinib Erlotinib Lapatinib Lenalidomide Sorafenib Sunitinib Valproic Acid | - | M.D. Anderson Cancer Center | |
| Valproic Acid With Chemoradiotherapy for Non-Small-Cell Lung Cancer | NCT01203735 | Locally Advance... | Valproic acid | 18 Years - 75 Years | Soroka University Medical Center | |
| Valproic Acid Plus Cisplatin and Cetuximab in Recurrent and/or Metastatic Squamous Cell Carcinoma of Head and Neck | NCT02624128 | Squamous Cell C... | Valproic Acid Cisplatin Cetuximab | 18 Years - | National Cancer Institute, Naples | |
| Preoperative Valproic Acid and Radiation Therapy for Rectal Cancer | NCT01898104 | Colorectal Canc... | preoperative ra... Valproic Acid Capecitabine | 18 Years - 70 Years | National Cancer Institute, Naples | |
| Valproic Acid and Platinum-based Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma | NCT01695122 | Head and Neck C... Oral Cavity Can... Oropharyngeal C... | Valproic Acid | - 65 Years | Instituto do Cancer do Estado de São Paulo | |
| Valproic Acid in Treating Patients With Kaposi's Sarcoma | NCT00075777 | Sarcoma | valproic acid | 18 Years - | AIDS Malignancy Consortium | |
| Adjuvant Valproate for High Grade Sarcomas | NCT01010958 | High Grade Sarc... | Valproic Acid | 18 Years - | Columbia University | |
| Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors | NCT00302159 | High Grade Glio... Brain Tumors | adjuvant therap... Temozolomide Valproic Acid Radiation thera... | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | |
| Azacitidine and Valproic Acid Plus Carboplatin in Patients With Ovarian Cancer | NCT00529022 | Solid Tumors | Azacitidine Valproic Acid Carboplatin | - | M.D. Anderson Cancer Center | |
| Valproic Acid in the Induction of EBV Lytic Cycle Antigen Expression in Nasopharyngeal Carcinoma | NCT00181220 | Nasopharyngeal ... | valproic acid | 18 Years - 75 Years | Johns Hopkins University | |
| Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases | NCT00437957 | Brain Metastase... | Temozolomide Valproic Acid Whole Brain Rad... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Azacitidine and Valproic Acid Plus Carboplatin in Patients With Ovarian Cancer | NCT00529022 | Solid Tumors | Azacitidine Valproic Acid Carboplatin | - | M.D. Anderson Cancer Center |
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