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Brief Title: HPV Prevalence in the Mouth and Oropharynx of the Tonsillectomy Population
Official Title: HPV Prevalence in the Mouth and Oropharynx of the Tonsillectomy Population
Study ID: NCT01330147
Brief Summary: The principal aim of this study is to provide vital current data on the prevalence, distribution and natural history of Human Papilloma Virus (HPV) infection in the mouth. This data is an essential requirement for the assessment, development and evaluation of cost effectiveness of prophylactic vaccination and screening programmes.
Detailed Description: Patients undergoing a tonsillectomy operation for non-cancerous reasons will be recruited for this study. They will be asked to complete two questionnaires (study and sexual practices), provide saliva, urine and a blood sample. Following anaesthesia, oropharyngeal brushings and a tonsillectomy will be performed and all the samples will be processed for evidence of HPV infection.
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University Hospitals Coventry & Warwickshire Trust, Coventry, England, United Kingdom
University Hospital Birmingham, Birmingham, West Midlands, United Kingdom
Birmingham City Hospital, Birmingham, , United Kingdom
Birmingham Children Hospital, Birmingham, , United Kingdom
Heartlands Hospital, Birmingham, , United Kingdom
Kidderminster Hospital, Kidderminster, , United Kingdom
New Cross Hospital, Wolverhampton, , United Kingdom
Worcestershire Royal Hospital, Worcester, , United Kingdom
Name: Hisham Mehanna, Prof
Affiliation: The University of Birmingham
Role: PRINCIPAL_INVESTIGATOR