Neoplasms

Mouth and Tooth Diseases

All Conditions

Infections

Respiratory Tract (Lung and Bronchial) Diseases

Ear, Nose, and Throat Diseases

Symptoms and General Pathology

Rare Diseases

Mouth Neoplasms

Tonsillitis

Pharyngitis

Communicable Diseases

Respiratory Tract Infections

Pharyngeal Diseases

Stomatognathic Diseases

Respiratory Tract Diseases

Otorhinolaryngologic Diseases

Chronic Graft Versus Host Disease

Oral Cancer

Lip and Oral Cavity Cancer

Subjects undergoing tonsillectomy for non-cancer reasons including operations for: recurrent tonsillitis, asymmetric tonsils, snoring surgery or obstructive sleep apnoea.

Hisham Mehanna, Prof

The principal aim of this study is to provide vital current data on the prevalence, distribution and natural history of Human Papilloma Virus (HPV) infection in the mouth. This data is an essential requirement for the assessment, development and evaluation of cost effectiveness of prophylactic vaccination and screening programmes.

Patients undergoing a tonsillectomy operation for non-cancerous reasons will be recruited for this study. They will be asked to complete two questionnaires (study and sexual practices), provide saliva, urine and a blood sample. Following anaesthesia, oropharyngeal brushings and a tonsillectomy will be performed and all the samples will be processed for evidence of HPV infection.

Oral rinse, Oral Mucosal Trasudate, Urine, Whole Blood, Nail brushings, Mouth brush biopsies (scrapes) and Tonsillectomy specimens

HPV Prevalence in the Mouth and Oropharynx of the Tonsillectomy Population

vaccination received yes/no and the type of vaccination description

GlaxoSmithKline

University of Birmingham

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
HPV Prevalence in the Mouth and Oropharynx of the Tonsillectomy Population	NCT01330147	Chronic Tonsill...		- 65 Years	University of Birmingham
HPV Prevalence in the Mouth and Oropharynx of the Tonsillectomy Population	NCT01330147	Chronic Tonsill...		- 65 Years	University of Birmingham

Spots Global Cancer Trial Database for chronic tonsillitis