Spots Global Cancer Trial Database for Efficacy of Pentoxifylline and Alpha Lipoic Acid in PCOS Resistant to Clomiphene Citrate
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Trial Identification
Brief Title: Efficacy of Pentoxifylline and Alpha Lipoic Acid in PCOS Resistant to Clomiphene Citrate
Official Title: Evaluation of the Effect of Pentoxifylline and α-Lipoic Acid as Adjunctive Therapy in Patients With Clomiphene Citrate Resistant Polycystic Ovary Syndrome
Study ID: NCT05231980
Study Description
Brief Summary: This study evaluate the addition of PTX and ALA to clomiphene citrate in the treatment of polycystic ovary.
Detailed Description: Clomiphene, PTX and ALA each used in treatment of pco but they do so by different mechanisms. Clomifene is in the selective estrogen receptor modulator (SERM) family of medication. It works by causing the release of gonadotropin-releasing hormone by the hypothalamus, and subsequently gonadotropin from the anterior pituitary. PTX and ALA are used in treatment of pco due its anti-oxidant effect.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Medical Center of Infertility, Banī Suwayf, , Egypt
College of Pharmacy Teaching Hospital Ainshams University, Cairo, , Egypt
Misr University For Sciences and Technology Teaching Hospital, Giza, , Egypt
Contact Details
Name: Nagwa Al Sabri, Phd
Affiliation: Ainshams university
Role: STUDY_DIRECTOR
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