Spots Global Cancer Trial Database for Oral Versus Parenteral Nutrition Support to Improve Protein Balance in Colorectal Surgical Patients
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Trial Identification
Brief Title: Oral Versus Parenteral Nutrition Support to Improve Protein Balance in Colorectal Surgical Patients
Official Title: Oral Versus Parenteral Perioperative Nutrition Support to Improve Protein Balance: Stable Isotope Study in Colorectal Surgical Patients
Study ID: NCT01222208
Conditions
Study Description
Brief Summary: A prospective, randomized controlled study, using stable isotope methodology, is proposed to determine whether an oral nutrition support regimen, containing pressurized whey protein and glucose, is more effective at normalizing the metabolic response to surgery than a standard peripheral parenteral nutrition (PPN) support regimen, containing amino acids and glucose, in colorectal surgical patients studied before and after surgery. The effectiveness of the nutrition support regimens will be determined by: whole body protein balance, synthesis rates of hepatic secretory proteins, resting energy expenditure and substrate utilization, as well as circulating metabolites concentrations.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Montreal General Hospital, Montreal, Quebec, Canada
Contact Details
Name: Franco Carli, M.D.
Affiliation: McGill University Health Centre/Research Institute of the McGill University Health Centre
Role: PRINCIPAL_INVESTIGATOR
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