Spots Global Cancer Trial Database for Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer
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Trial Identification
Brief Title: Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer
Official Title: Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer
Study ID: NCT00516230
Conditions
Interventions
Study Description
Brief Summary: Correct identification of Lynch syndrome at the time of colorectal cancer presentation is important. We aim to find best ways to screen patients with colorectal cancer in Korea.
Detailed Description: Patients with newly diagnoised colorectal cancer will be eligible. They will undergo detailed history taking including family history, and molecular stuidies including microsatellite instability test and immunohistochemistry for DNA mismatch repair protein with pre-selection. Any abnormal finding in molecular stuides will be offered genetic testing (after testing methylation status for patients with abnormalities in MLH1).
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Samsung Medical Center, Seoul, Gangnam-gu, Korea, Republic of
Contact Details
Name: Dong Kyung Chang, M.D. Ph.D
Affiliation: Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
Role: PRINCIPAL_INVESTIGATOR
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