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Brief Title: EO4010 in Previously Treated Metastatic Colorectal Carcinoma
Official Title: A Global Multicenter Phase 1/2 Trial of EO4010, a Novel Microbial Derived Peptide Therapeutic Vaccine, in Combination With Nivolumab, for Treatment of Patients With Previously Treated Metastatic Colorectal Carcinoma
Study ID: NCT05589597
Brief Summary: Open-label multicenter study
Detailed Description: This is an open-label, multicenter, FIH, phase 1/2 trial to assess safety, tolerability, immunogenicity, and preliminary efficacy of the microbial-derived therapeutic vaccine EO4010 in combination with nivolumab for treatment of patients with unresectable, previously treated, metastatic colorectal cancer
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
MD Anderson, Houston, Texas, United States
Hôpital Jean Minjoz, Besançon, , France
ICM Val d'Aurelle, Montpellier, , France
Saint Antoine hospital, Paris, , France
Hospital Universitari Vall d'Hebron, Barcelona, , Spain
Name: Jan Fagerberg
Affiliation: Enterome
Role: STUDY_DIRECTOR