Spots Global Cancer Trial Database for colorectal cancer metastatic
Every month we try and update this database with for colorectal cancer metastatic cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Possible Association of Intestinal Helminths and Protozoa With Colorectal Cancer Pathogenesis | NCT03173001 | Colorectal Canc... Colorectal Canc... Intestinal Para... Protozoan Infec... | Parasitological... | 18 Years - 90 Years | Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan | |
| Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis | NCT04157322 | Colorectal Canc... Colorectal Canc... Colorectal Canc... Appendix Cancer | prospective sin... | 18 Years - | University of Chicago | |
| Sym004 Versus TAS-102 in Patients With mCRC | NCT03717038 | Metastatic Colo... Colorectal Canc... Carcinoma | Sym004 TAS-102 | 18 Years - | Symphogen A/S | |
| Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy | NCT06414304 | Colorectal Canc... Colorectal Canc... MSI-H Colorecta... dMMR Colorectal... Cancer Colon Adenocarc... | 18 Years - | OncoAtlas LLC | ||
| Anticancer Vigilance Of Cardiac Events (AVOCETTE) in Metastatic Colorectal Cancer | NCT03923036 | Colorectal Canc... | Antineoplastic ... | 18 Years - | University Hospital, Caen | |
| Irinotecan Drug-eluting Bead Liver Embolisation Registry | NCT03697044 | Colorectal Canc... Liver Metastase... | Irinotecan Drug... | 18 Years - 80 Years | The Christie NHS Foundation Trust | |
| Study of Aflibercept as Maintenance Therapy Following Induction With Aflibercept in Combination With XELOX, as First-Line Treatment for Metastatic Colorectal Cancer Patient | NCT01955629 | Colorectal Canc... | Aflibercept AVE... Oxaliplatin Capecitabine | 18 Years - | Sanofi | |
| Registry Platform Colorectal Cancer | NCT04867525 | Colorectal Canc... | Physician's cho... | 18 Years - | iOMEDICO AG | |
| Expanded Access Study of TAS-102 in Patients With Metastatic Colorectal Cancer | NCT02286492 | Colorectal Canc... | TAS-102 | 18 Years - | Taiho Oncology, Inc. | |
| Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy | NCT03007407 | Colorectal Canc... | durvalumab Tremelimumab | 18 Years - | NSABP Foundation Inc | |
| Sym004 Versus Futuximab or Modotuximab in Patients With mCRC | NCT03549338 | Metastatic Colo... Colorectal Canc... Carcinoma | Sym004 Futuximab Modotuximab | 18 Years - | Symphogen A/S | |
| FOLFIRI in Combination With Cetuximab in the First-line Treatment of Metastatic Colorectal Cancer Including a Regular Dermal Prophylaxis to Prevent Acneiforme Follicular Exanthema | NCT01315990 | Colorectal Canc... | FOLFIRI + Cetux... | 18 Years - | Johannes Gutenberg University Mainz | |
| A Phase 2 Study of Lamivudine in Patients With p53 Mutant Metastatic Colorectal Cancer | NCT03144804 | Colorectal Canc... | Lamivudine | 18 Years - | Massachusetts General Hospital | |
| The Oncopanel Pilot (TOP) Study | NCT02171286 | Colorectal Canc... Advanced Non-Sm... Advanced Melano... Gastrointestina... Patients With D... | 18 Years - | British Columbia Cancer Agency | ||
| Chemotherapy Alone Versus Chemotherapy Plus Targeted Therapy as Adjuvant Therapy for Initially Unresectable Colorectal Cancer Liver Metastases | NCT06027775 | Colorectal Canc... | Targeted agent | 18 Years - 75 Years | Fudan University | |
| Intraperitoneal and System Chemotherapy Versus XELOX as First-line Chemotherapy for mCRC | NCT03792269 | Colorectal Canc... Chemotherapy Ef... Chemotherapeuti... | Irinotecan Oxaliplatin Capecitabine | 18 Years - | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | |
| Explore Biomarkers Associated With Prognosis of Recurrent and Metastatic CRC After Surgery by Multi-omics Methods | NCT05501353 | Colorectal Canc... | no intervention | 18 Years - 99 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University | |
| A Phase 1b Study of WU-NK-101 in Combination With Cetuximab | NCT05674526 | Colorectal Canc... Squamous Cell C... | WU-NK-101 - Dos... Cetuximab - Dos... WU-NK-101 - Coh... Cetuximab - Coh... | 18 Years - | Wugen, Inc. | |
| Assessing How Normal Variations in CT Scanning Affects Its Interpretation | NCT03038568 | Colorectal Canc... | CT scan | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab in Patients With Resectable Liver Metastases | NCT01508000 | Colorectal Canc... Liver Metastase... KRAS Wild Type ... | FOLFOX6 Bevacizumab Panitumumab Surgery | 18 Years - 75 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Radiotherapy Combined With Tislelizumab and Irinotecan in MSS/pMMR Recurrence and Metastatic Colorectal Cancer | NCT05160727 | Mismatch Repair... Colorectal Canc... Microsatellite ... | Tislelizumab Irinotecan radiotherapy | 18 Years - 70 Years | Zhejiang Cancer Hospital | |
| EO4010 in Previously Treated Metastatic Colorectal Carcinoma | NCT05589597 | Colorectal Canc... | EO4010 | 18 Years - | Enterome | |
| Development of an IDEAL Framework to Standardise Cytoreductive Surgery for Colorectal Peritoneal Metastases | NCT03733184 | Colorectal Canc... Peritoneal Meta... | Cytoreduction a... | 18 Years - 90 Years | University of Manchester | |
| Feasibility Study of a 4 Stage Bowel Obstruction Cancer Diet | NCT04898842 | Colorectal Canc... Colorectal Neop... Colorectal Carc... Colorectal Aden... Colorectal Canc... Ovarian Cancer Ovarian Neoplas... Metastatic Colo... Metastatic Ovar... Peritoneal Carc... Bowel Obstructi... | Dietary interve... | 18 Years - | Royal Surrey County Hospital NHS Foundation Trust | |
| A Pilot Study to Explore the Role of Gut Flora in Colorectal Cancer | NCT04148378 | Colorectal Canc... Colorectal Neop... Colorectal Carc... Colorectal Aden... Colorectal Canc... Colorectal Sarc... | No intervention | - | ProgenaBiome | |
| Evaluation of the Safety and the Tolerability of Durvalumab Plus Tremelimumab Combined With FOLFOX in mCRC | NCT03202758 | Colorectal Canc... | Durvalumab, Tre... | 18 Years - | Centre Georges Francois Leclerc | |
| A Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Subjects With Metastatic Colorectal Cancer | NCT05759728 | Colorectal Canc... | CNA3103: 5 x 10... CNA3103: 1.5 x ... CNA3103: 4.5 x ... CNA3103: 1.5 x ... CNA3103: 2.5 x ... | 18 Years - | Carina Biotech Limited | |
| METIMMOX: Colorectal Cancer METastasis - Shaping Anti-tumor IMMunity by OXaliplatin | NCT03388190 | Colorectal Canc... | Nivolumab FLOX | 18 Years - | University Hospital, Akershus | |
| Phase 2 Study of DKN-01 in Colorectal Cancer | NCT05480306 | Colorectal Canc... Colorectal Aden... Colo-rectal Can... Colorectal Canc... | DKN-01 FOLFIRI Bevacizumab FOLFOX | 18 Years - | Leap Therapeutics, Inc. | |
| Prospective Cohort Study of Immunotherapy Resistance in Metastatic Colorectal Cancer Patients With MSI | NCT06353854 | Colorectal Canc... Microsatellite ... | 18 Years - | Federation Francophone de Cancerologie Digestive | ||
| To Assess the Safety of Continuous IV Administration of Plerixafor in Patients With Advanced Pancreatic, Ovarian and Colorectal Cancers | NCT02179970 | Pancreatic Aden... Ovarian Serous ... Colorectal Canc... | Plerixafor | 16 Years - | Cambridge University Hospitals NHS Foundation Trust | |
| A Study of EDP1503 in Patients With Colorectal Cancer, Breast Cancer, and Checkpoint Inhibitor Relapsed Tumors | NCT03775850 | Colorectal Canc... Triple Negative... Non Small Cell ... Bladder Cancer GastroEsophagea... Renal Cell Carc... MSI-H | EDP1503 Pembrolizumab | 18 Years - | Evelo Biosciences, Inc. | |
| Efficacy and Safety of Raltitrexed-based Transarterial Chemoembolisation(TACE)for Colorectal Cancer Liver Metastases | NCT01959061 | Colorectal Canc... | Raltitrexed Oxaliplatin lipiodol | 18 Years - 75 Years | Nanjing Chia-tai Tianqing Pharmaceutical | |
| Assessing How Normal Variations in CT Scanning Affects Its Interpretation | NCT03038568 | Colorectal Canc... | CT scan | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| LY3200882 and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer (EORTC1615) | NCT04031872 | Colorectal Canc... | LY3200882 | 18 Years - | The Netherlands Cancer Institute | |
| Study of Intratumoral Ipilimumab and TLR4 Agonist GLA-SE in Combination With Systemic Nivolumab and Chemotherapy | NCT03982121 | Colorectal Canc... | FOLFOX regimen Nivolumab Ipilimumab GLA-SE | 18 Years - | Gustave Roussy, Cancer Campus, Grand Paris | |
| A Study of EDP1503 in Patients With Colorectal Cancer, Breast Cancer, and Checkpoint Inhibitor Relapsed Tumors | NCT03775850 | Colorectal Canc... Triple Negative... Non Small Cell ... Bladder Cancer GastroEsophagea... Renal Cell Carc... MSI-H | EDP1503 Pembrolizumab | 18 Years - | Evelo Biosciences, Inc. | |
| Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy | NCT06414304 | Colorectal Canc... Colorectal Canc... MSI-H Colorecta... dMMR Colorectal... Cancer Colon Adenocarc... | 18 Years - | OncoAtlas LLC | ||
| Possible Association of Intestinal Helminths and Protozoa With Colorectal Cancer Pathogenesis | NCT03173001 | Colorectal Canc... Colorectal Canc... Intestinal Para... Protozoan Infec... | Parasitological... | 18 Years - 90 Years | Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan | |
| FOLFOXIRI Plus Panitumumab in Metastatic RAS Wild-type, Left-sided Colorectal Cancer | NCT04169347 | Colorectal Canc... | Oxaliplatin | 18 Years - | Criterium, Inc. | |
| Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases | NCT05248581 | Colorectal Canc... | Liver transplan... | 18 Years - | University of Rochester | |
| Phase 2 Study of DKN-01 in Colorectal Cancer | NCT05480306 | Colorectal Canc... Colorectal Aden... Colo-rectal Can... Colorectal Canc... | DKN-01 FOLFIRI Bevacizumab FOLFOX | 18 Years - | Leap Therapeutics, Inc. | |
| Efficacy and Safety of Raltitrexed-based Transarterial Chemoembolisation(TACE)for Colorectal Cancer Liver Metastases | NCT01959061 | Colorectal Canc... | Raltitrexed Oxaliplatin lipiodol | 18 Years - 75 Years | Nanjing Chia-tai Tianqing Pharmaceutical | |
| Study to Evaluate Real-world Pharmacoeconomics and Resistance Mechanisms of Panitumumab in Metastatic Colorectal Cancer Patients | NCT02135757 | Colorectal Canc... | 18 Years - | PeriPharm | ||
| Holmium-166 TARE in Liver Limited Unresectable Colorectal Cancer Patients | NCT06332079 | Colorectal Canc... | 166Holmium TARE Cetuximab Panitumumab 5-Fluorouracil Bevacizumab Capecitabine | 18 Years - | Gruppo Oncologico del Nord-Ovest | |
| Evaluation of Tumour Growth and Oncological Treatment in Patients With CRLM Using Zebra Fish Embryo Model | NCT05289076 | Colorectal Canc... Tumour Metastas... Chemotherapy Ef... Tumor Growth | Chemotherapy dr... | 18 Years - | University Hospital, Linkoeping | |
| A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer | NCT03597581 | Gastrointestina... Gastrointestina... Colorectal Canc... Colorectal Neop... Colorectal Carc... Gastric Cancer Gastric Neoplas... KRAS Mutation-R... CRC Colorectal Canc... | ompenaclid FOLFIRI Bevacizumab FOLFOX regimen | 18 Years - | Inspirna, Inc. | |
| The Effects of General Anesthetics on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and Mechanism Involved | NCT03193710 | Colorectal Canc... Survival Rate General Anesthe... Lymphocyte Dest... Molecular Mecha... | Propofol Sevoflurane Remifentanil | 18 Years - 65 Years | West China Hospital | |
| To Assess the Safety of Continuous IV Administration of Plerixafor in Patients With Advanced Pancreatic, Ovarian and Colorectal Cancers | NCT02179970 | Pancreatic Aden... Ovarian Serous ... Colorectal Canc... | Plerixafor | 16 Years - | Cambridge University Hospitals NHS Foundation Trust | |
| Ipilimumab, Maraviroc and Nivolumab in Advanced Metastatic Colorectal and Pancreatic Cancer the LUMINESCENCE Trial | NCT04721301 | Colorectal Canc... Pancreatic Canc... | Nivolumab plus ... | 18 Years - | University Hospital Heidelberg | |
| Evaluation of the Efficacy of Two Guidance Techniques (Standard Injected CT vs Porto-scanner With Angio-CT) for Thermoablation Treatment of Colorectal Cancer Liver Metastases | NCT05665322 | Colorectal Canc... | Thermoablation ... Thermoablation ... | 18 Years - | Centre Hospitalier Universitaire de Nīmes | |
| Effectiveness Study of Resection of Primary Tumor in Stage IV Colorectal Cancer Patients | NCT02149784 | Colorectal Canc... | Surgical resect... | 18 Years - 75 Years | Sun Yat-sen University | |
| Neoantigen-Targeted Vaccine Combined With Anti-PD-1 Antibody for Patients With Stage IV MMR-p Colon and Pancreatic Ductal Cancer | NCT04799431 | Pancreatic Canc... Colorectal Canc... | Neoantigen Vacc... Retifanlimab | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Colorectal Cancer Metastatic | NCT01670721 | Colorectal Canc... | AFLIBERCEPT Irinotecan Fluorouracil Leucovorin | 18 Years - | Sanofi | |
| Zinc Supplement in Regorafenib Treated mCRC Patient | NCT03898102 | Colorectal Canc... | Regorafenib Zinc gluconate ... | 20 Years - | Chang Gung Memorial Hospital | |
| Maintenance Metronomic Chemotherapy for Metastatic Colorectal Carcinoma | NCT01668680 | Colorectal Canc... | CAPECITABINE, C... | 18 Years - 80 Years | HaEmek Medical Center, Israel | |
| Feasibility of 2 Interventions to Reduce Fatigue in Patients With Chemotherapy for Metastatic Colorectal Cancer | NCT04999306 | Colorectal Canc... | Hypnosis CBT | 18 Years - | Institut du Cancer de Montpellier - Val d'Aurelle | |
| Holmium-166 TARE in Liver Limited Unresectable Colorectal Cancer Patients | NCT06332079 | Colorectal Canc... | 166Holmium TARE Cetuximab Panitumumab 5-Fluorouracil Bevacizumab Capecitabine | 18 Years - | Gruppo Oncologico del Nord-Ovest | |
| Evaluation of the Safety and the Tolerability of Durvalumab Plus Tremelimumab Combined With FOLFOX in mCRC | NCT03202758 | Colorectal Canc... | Durvalumab, Tre... | 18 Years - | Centre Georges Francois Leclerc | |
| Evaluation of the Efficacy of Two Guidance Techniques (Standard Injected CT vs Porto-scanner With Angio-CT) for Thermoablation Treatment of Colorectal Cancer Liver Metastases | NCT05665322 | Colorectal Canc... | Thermoablation ... Thermoablation ... | 18 Years - | Centre Hospitalier Universitaire de Nīmes | |
| Early Detection of Treatment Failure in Metastatic Colorectal Cancer Patients | NCT05068531 | Colorectal Canc... | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | ||
| Regorafenib and PD-1 Antibody in Combination With Radiotherapy for pMMR/MSS Metastatic Colorectal Cancer | NCT04030260 | Colorectal Canc... MSS | Regorafenib and... Radiation thera... | 18 Years - 70 Years | Sun Yat-sen University | |
| OPTImal PALliative Anti-epidermal Growth Factor Receptor Treatment in Metastatic Colorectal Cancer - | NCT03750175 | Colorectal Canc... Circulating Tum... KRAS Gene Mutat... NRAS Gene Mutat... BRAF Gene Mutat... Epidermal Growt... | Plasma circulat... | 18 Years - | Aarhus University Hospital | |
| Masitinib in Combination With FOLFIRI in Third or Fourth Line of Treatment of Patients With Metastatic Colorectal Cancer | NCT03556956 | Colorectal Canc... | Masitinib | 18 Years - | AB Science | |
| Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer | NCT04245865 | Colorectal Canc... | Fluorouracil Calcium folinat... Oxaliplatin Bevacizumab Capecitabine Tocotrienol Placebo | 18 Years - | Vejle Hospital | |
| Monocentric Prospective Pilot Study Evaluating the Value of Indocyanine Green (ICG, Indocyanine Green) During a Surgical Resection of Cancerous Lesions Peritoneal Colorectal Origin. | NCT01982227 | Colorectal Canc... | indocyanine gre... | 18 Years - 70 Years | Centre Hospitalier Universitaire de Saint Etienne | |
| Colorectal Cancer Metastatic | NCT01670721 | Colorectal Canc... | AFLIBERCEPT Irinotecan Fluorouracil Leucovorin | 18 Years - | Sanofi | |
| The Oncopanel Pilot (TOP) Study | NCT02171286 | Colorectal Canc... Advanced Non-Sm... Advanced Melano... Gastrointestina... Patients With D... | 18 Years - | British Columbia Cancer Agency | ||
| Radioembolization in Elderly/ Fragile Patients With mCRC | NCT05092880 | Colorectal Canc... | radioembolizati... Standard of car... | 18 Years - | UMC Utrecht | |
| Combined Anticancer Treatment of Advanced Colon Cancer | NCT01540344 | Peritoneal Carc... Colorectal Canc... | CRS HIPEC | 18 Years - 71 Years | University of Regensburg | |
| A Study of Famitinib in Patients With Advanced Colorectal Cancer | NCT01762293 | Colorectal Canc... Colorectal Canc... Colorectal Canc... | Famitinib placebo | 18 Years - 70 Years | Jiangsu HengRui Medicine Co., Ltd. | |
| Maintenance Treatment Versus Observation After Induction in Advanced Colorectal Carcinoma | NCT00442637 | Colorectal Canc... | capecitabine + ... observation | 18 Years - | Dutch Colorectal Cancer Group | |
| Ipilimumab, Maraviroc and Nivolumab in Advanced Metastatic Colorectal and Pancreatic Cancer the LUMINESCENCE Trial | NCT04721301 | Colorectal Canc... Pancreatic Canc... | Nivolumab plus ... | 18 Years - | University Hospital Heidelberg | |
| Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases | NCT03488953 | Colorectal Canc... Liver Metastase... | Living donor li... | 18 Years - | Jena University Hospital | |
| Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer | NCT03657641 | Colorectal Canc... Colorectal Canc... | Pembrolizumab Regorafenib | 18 Years - | University of Southern California | |
| Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer. | NCT05243862 | Colorectal Canc... | PolyPEPI1018 Atezolizumab | 18 Years - | Treos Bio Limited | |
| Local Consolidative Therapy in Colorectal Cancer | NCT05062720 | Colorectal Canc... | Local consolida... | 18 Years - | Fox Chase Cancer Center | |
| Ipilimumab, Maraviroc and Nivolumab in Advanced Metastatic Colorectal and Pancreatic Cancer the LUMINESCENCE Trial | NCT04721301 | Colorectal Canc... Pancreatic Canc... | Nivolumab plus ... | 18 Years - | University Hospital Heidelberg | |
| The p53 Colorectal Cancer Trial | NCT03149679 | Colorectal Canc... Colorectal Canc... TP53 Gene Mutat... | Cyclophosphamid... | 18 Years - | Haukeland University Hospital | |
| Combined Anticancer Treatment of Advanced Colon Cancer | NCT01540344 | Peritoneal Carc... Colorectal Canc... | CRS HIPEC | 18 Years - 71 Years | University of Regensburg |
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