Spots Global Cancer Trial Database for Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer
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Trial Identification
Brief Title: Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer
Official Title: A Phase III Clinical Trial Evaluating TheraSphere® in Patients With Metastatic Colorectal Carcinoma of the Liver Who Have Failed First Line Chemotherapy
Study ID: NCT01483027
Conditions
Interventions
Study Description
Brief Summary: The effectiveness and safety of TheraSphere will be evaluated in patients with colorectal cancer with metastases in the liver, who are scheduled to receive second line chemotherapy. All patients receive the standard of care chemotherapy with or without the addition of TheraSphere.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Alabama at Birmingham, Birmingham, Alabama, United States
University of California San Fransico, Moffitt Hospital, San Francisco, California, United States
University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, United States
Christiana Care Hospital, Newark, Delaware, United States
Lynn Clinical Research Center, Boca Raton Regional Hospital, Boca Raton, Florida, United States
University of Miami Miller School of Medicine, Florida, Miami, Florida, United States
Moffit Cancer Center, Tampa, Florida, United States
Northwestern University, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
Carle Clinic, Urbana, Illinois, United States
Indiana University School of Medicine, Indianapolis, Indiana, United States
University of Louisville, Louisville, Kentucky, United States
University of Michigan Health System, Ann Arbor, Michigan, United States
Wayne State Harper Hospita Karmanos Cancer Institute, Farmington Hills, Michigan, United States
Spectrum Health, Grand Rapids, Michigan, United States
Beaumont Hospital, Royal Oak, Michigan, United States
Allina Health, Virginia Piper Cancer Institute, Minneapolis, Minnesota, United States
Minneapolis, Minneapolis, Minnesota, United States
Mayo Clinic, Rochester, Minnesota, United States
Mallinckrodt Institute of Radiology, Saint Louis, Missouri, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
University of Rochester, Rochester, New York, United States
Cleveland Clinic Foundation, Cleveland, Ohio, United States
The Ohio State University, Wexner Medical Center, Columbus, Ohio, United States
Miami Valley Hospital, Dayton, Ohio, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Aria Health, Trevose, Pennsylvania, United States
UT Southwestern Medical Center, Dallas, Texas, United States
UT MD Anderson Cancer Center, Houston, Texas, United States
St. Marks Hospital, Salt Lake City, Utah, United States
Sentara Norfolk General, Norfolk, Virginia, United States
University of Washington, Seattle, Washington, United States
Gundersen Medical Foundation, La Crosse, Wisconsin, United States
Medical College of Wisconsin/Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin, United States
Aurora Research Institute, Wauwatosa, Wisconsin, United States
Medical University of Vienna, Vienna, , Austria
Onze-Lieve-Vrouwziekenuis VZW Campus Aalst, Aalst, , Belgium
AZ - Sint Lucas, Gent, , Belgium
Universitair Ziekenhuis Gent, Gent, , Belgium
AZ Groeninge, Kortrijk, , Belgium
Tom Baker Cancer Centre, Calgary, Alberta, Canada
QEII Health Services Center, Halifax Infirmary Site, Halifax, Nova Scotia, Canada
London Regional Cancer program, London, Ontario, Canada
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
University Health Network , Mount Sinai Hospital, Toronto, Ontario, Canada
McGill University Health Center - Glen Site, Montreal, Quebec, Quebec, Canada
Royal University Hospital, Saskatoon, Saskatchewan, Canada
Hong Kong Sanatorium Hospital, Hong Kong, , China
Queen Mary Hospital, Hong Kong, , China
CHRU Montpellier - Hopital St Eloi, Montpellier, Cedex 5, France
CUH d'Angers, Angers, Cedex 9, France
CHU Toulouse, Hôpital Rangueil, Toulouse, Cedex 9, France
Institut Bergognié, Bordeaux, , France
Hôpital Beaujon, Clichy, , France
Hôpital Henri Mondor, Créteil, , France
Centre Georges Francois Leclerc, Dijon cedex, , France
Centre Hospitalier Lyon-Sud, Lyon, , France
Hôpital La Timone, Marseille, , France
CHU Nantes-Hôtel Dieu, Nantes, , France
CHU de Nice,, Hopital Archet 2 - Service d'Imagerie Médicale niveau -2, Nice, , France
CHU Bordeaux, Pessac, , France
Hôpital La Milétrie, CHU Poitiers, hépato gastroenterologie, Poitiers, , France
Centre Eugene Marquis, Rennes, , France
Universitätsklinikum Bonn, Bonn,, , Germany
Universitätsklinikum Essen, Essen, , Germany
Medizinische Hochschule Hannover, Hannover, , Germany
SLK Kliniken, Heilbronn GmbH, Heilbronn, , Germany
Universitätsklinikum des Saarlandes, Homburg, , Germany
University Hospital of Leipzig, Leipzig, , Germany
Universitaetsklinikum Marburg Klinik für Dermatologie und Allergologie, Marburg, , Germany
Eberhard-Karls-University Tübingen, Tübingen, , Germany
Azienda Ospedaliera-Universitaria, Policlinico Sant'Orsola Malpighi, Bologna, , Italy
Gangnam Severance Hospital, Seoul, , Korea, Republic of
Korea University Anam Hospital, Seoul, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Seoul, , Korea, Republic of
St. Mary's Hospital, Seoul, , Korea, Republic of
Białostockie Centrum Onkologii, Bialystok, , Poland
Centrum Onkologii - Instytut, im. Marii Skłodowskiej-Curie, Gliwice, , Poland
Regionalny Szpital Specjalistyczny im. Dr Władysława Biegańskiego, Grudziądz, , Poland
Oddział Onkologii Klinicznej; Centrum Onkologii Ziemi Lubelskiej im. Św.Jana z Dukli., Lublin, , Poland
Szpital Kliniczny im. Heliodora Święcickiego, Poznan, , Poland
Centralny Szpital Kliniczny MSWiA, Warszawa, , Poland
Centrum Onkologii - Instytut, Warszawa, , Poland
Wojskowy Instytut Medyczny, Warszawa, , Poland
National University Hospital, Singapore, , Singapore
Hospital Universitario Fundación Alcorcón, Alcorcón, , Spain
Hospital Universitari Vall d'Hebron, Barcelona,, , Spain
Hospital de la Santa Creu i Sant Pau, Barcelona, , Spain
Hospital Clinic de Barcelona, Barcelona, , Spain
Hospital Universitario del Henares, Coslada, , Spain
Hospital Universitario de Fuenlabrada, Fuenlabrada, , Spain
Hospital Universitario Virgen de las Nieves, Granada, , Spain
Hospital General Universitario Gregorio Marañón, Madrid, , Spain
Hospital Universitario Ramon y Cajal, Madrid, , Spain
Hospital Fundación Jiménez Díaz, Madrid, , Spain
Hospital Universitario Puerta de Hierro, Madrid, , Spain
Hospital Regional Universitario de Málaga - Hospital General, Malaga, , Spain
Hospital Universitario Virgen de la Arrixaca, Murcia,, , Spain
Avenida de Roma, s/n, Hospital Universitario Central de Asturias, Oviedo, , Spain
Hospital Universitario Central de Asturias, Oviedo, , Spain
Parc Taulí Sabadell Hospital Universitari, Sabadell, , Spain
Hospital Universitari i Politècnic La Fe, Valencia, , Spain
HCU Lozano Blesa, Planta 11-Oncología-Secretaría, Zaragoza, , Spain
NHS Grampian - Aberdeen Royal Infirmary, Aberdeen, , United Kingdom
Royal United Hospital Bath NHS Trust, Bath, , United Kingdom
The Clatterbrdige Cancer Centre NHSF Trust, Bebington, , United Kingdom
Queen Elizabeth Hospital Cancer Centre, Birmingham, , United Kingdom
The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust - Royal Bournemouth Hospital, Bournemouth, , United Kingdom
University Hospitals Bristol NHS Foundation Trust - Bristol Haematology and Oncology Centre, Bristol, , United Kingdom
Cambridge University Hospitals NHS Foundation Trust - Addenbrookes Hospital, Cambridge, , United Kingdom
Velindre Cancer Centre, Cardiff, , United Kingdom
Western General Hospital, Edinburgh, , United Kingdom
Beatson Cancer Centre and University of Glasgow, Glasgow,, , United Kingdom
University of Glasgow, Glasgow, , United Kingdom
Royal Surrey County Hospital, Guildford, , United Kingdom
Calderdale and Huddersfield NHS Foundation Trust - Huddersfield Royal Infirmary, Huddersfield, , United Kingdom
Leeds Hospitals NHS Trust, Leeds, , United Kingdom
UCLH, University College London Hospitals, London, , United Kingdom
Guy's and St Thomas' NHS Foundation Trust, London, , United Kingdom
The Christie NHS Foundation Trust, Manchester, , United Kingdom
The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, , United Kingdom
Nottingham University Hospital NHS Trust, Nottingham, , United Kingdom
Oxford University Hospitals NHS Foundation Trust Churchill Hospital, Oxford, , United Kingdom
Barking, Havering and Redbridge University Hospitals NHS Trust - Queen's Hospital, Romford, , United Kingdom
Western Park Hospital, Sheffield, , United Kingdom
Southampton General Hospital, Southampton, , United Kingdom
Great Western Hospitals NHS Foundation Trust - The Great Western Hospital, Swindon, , United Kingdom
Taunton and Somerset NHS Foundation Trust - Musgrove Park Hospital, Taunton, , United Kingdom
Walsall Healthcare NHS Trust - Manor Hospital, Walsall, , United Kingdom
The Royal Wolverhampton NHS Trust - New Cross Hospital, Wolverhampton, , United Kingdom
Contact Details
Name: Mary F Mulcahy, MD
Affiliation: Northwestern University
Role: PRINCIPAL_INVESTIGATOR
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