Spots Global Cancer Trial Database for Impact of Probiotics in Modulation of Intestinal Microbiota
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Trial Identification
Brief Title: Impact of Probiotics in Modulation of Intestinal Microbiota
Official Title: Impact of Probiotics in Modulation of Intestinal Microbiota of Patients Undergoing a Resection Colonic
Study ID: NCT01895530
Conditions
Interventions
Study Description
Brief Summary: The investigators would study about impact of the administration of probiotics in the intestinal mucosa of patients undergoing resection colic, by evaluating cytokine profile by quantitative real time PCR. The investigators believe that patients who use probiotic preoperative would provide cytokine profile less inflammatory than those of the control group.
Detailed Description: Samples of colorectal cancer-free mucosa derived from patients who underwent surgical resection were investigated. Quantitative real-time polymerase chain reaction (RT-qPCR) was used to determine expression levels of the following genes: IL10, IL1B, IL23A, TNF, IL12B, INFG, IL17A.
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
UFMG Hospital, Belo horizonte, Minas Gerais, Brazil
Contact Details
Name: Isabel TD Correia, PhD
Affiliation: Federal University of Minas Gerais
Role: STUDY_DIRECTOR
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