Spots Global Cancer Trial Database for Study on the Diagnostic Value of Multi-omics Combined Detection for Precancerous Lesions of CRC
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Trial Identification
Brief Title: Study on the Diagnostic Value of Multi-omics Combined Detection for Precancerous Lesions of CRC
Official Title: Study on the Diagnostic Value of Multi-omics Combined Detection for Precancerous Lesions of Colorectal Cancer
Study ID: NCT05530746
Interventions
Study Description
Brief Summary: Colorectal cancer (CRC) has become one of the most common malignant tumors in the world, and the key to its prevention and control is early detection and treatment. As colorectal adenoma and inflammatory bowel disease (IBD) are the inevitable precursors of most CRC, screening for colorectal adenoma and IBD is of great importance for preventing CRC. The existing detection methods have high sensitivity for CRC, while limited in colorectal adenoma and IBD. Therefore, exploring a detection method with high sensitivity for colorectal adenoma and IBD is necessary. This project intends to use methylation detection technology, lactic acid modified omics, proteomics, metagenomics, and other omics technology, through the analysis of differences in feces and histological results in healthy volunteers, patients with non-advanced adenoma, patients with advanced adenomas, patients with IBD, and patients with CRC for early screening.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Changhai Hospital, Naval Medical University, Shanghai, , China
Contact Details
Name: Zhaoshen Li, M.D
Affiliation: Study Principal Investigator
Role: PRINCIPAL_INVESTIGATOR
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