Spots Global Cancer Trial Database for Identification the Expression of Sox2 in Colorectal Cancer Tissues
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Trial Identification
Brief Title: Identification the Expression of Sox2 in Colorectal Cancer Tissues
Official Title: The Role of Sox2 in Tumor Genesis and Migration in Colorectal Cancer
Study ID: NCT01589900
Conditions
Interventions
Study Description
Brief Summary: Sox2 has been studied in several types of human solid tumors. The investigators found that Sox2 had higher expression level in colorectal cancer and metastatic tissues than normal tissues. So the investigators assumed that whether Sox2 plays an important role in the progression and migration of colon cancer.
Detailed Description: In our study, we examined Sox2 expression in archived human colon cancer tissues and found that its Sox2 expression correlates with reduced patient survival, increased tumor grade and metastasis probability.
Eligibility
Minimum Age: 24 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Contact Details
Name: Yan Zhang, M.D.Ph.D
Affiliation: Laboratory of Cancer and Stem Cell Biology School of Life Sciences Sun Yat-sen University
Role: PRINCIPAL_INVESTIGATOR
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