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Spots Global Cancer Trial Database for Prospective Study of Children and Adolescents With Craniopharyngioma

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Trial Identification

Brief Title: Prospective Study of Children and Adolescents With Craniopharyngioma

Official Title: KRANIOPHARYNGEOM 2007 - Multicenter Prospective Study of Children and Adolescents With Craniopharyngioma

Study ID: NCT01272622

Study Description

Brief Summary: The present investigation is a prospective, multicenter study evaluating craniopharyngioma patients' prognoses following the various currently-practiced therapeutic strategies.Primary goals of the study are to establish quality standards and compare the various therapy strategies with respect to their effectiveness and impact on the quality of life of treated patients. A stratified randomization of two treatment arms will be conducted with respect to timing of postoperative irradiation for the subgroup of patients ≥5 years of age whose tumors are incompletely resected. The researchers will investigate whether an immediate, postoperative irradiation is superior to progression-contingent irradiation based on alterations to quality of life (PEDQOL) from the time randomization is initiated (3rd month post op) to 3 years after randomization. Progression-free survival and overall survival will be examined as closely-related subgoals.Postoperative data will be evaluated via a surveillance study for all complete resection patients as well as for those patients under 5 years of age regardless of their resection grade.

Detailed Description:

Eligibility

Minimum Age: 1 Day

Eligible Ages: CHILD, ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Klinikum Oldenburg, Oldenburg, Niedersachsen, Germany

Contact Details

Name: Hermann L Müller, MD

Affiliation: Klinikum Oldenburg gGmbH

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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