Spots Global Cancer Trial Database for neurosurgery
Every month we try and update this database with for neurosurgery cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases | NCT01169129 | Metastases Cancer | surgery radiosurgery | 18 Years - 64 Years | Barretos Cancer Hospital | |
| Bevacizumab With or Without Surgery for Adult Glioblastomas | NCT01413438 | Glioblastoma Brain Neoplasm | Craniotomy | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Dendritic Cell Cancer Vaccine for High-grade Glioma | NCT01213407 | Glioblastoma Mu... | Trivax, Temozol... Temozolomide, S... | 3 Years - 70 Years | Activartis Biotech | |
| OCT-angiography as a Pronostic Marker for Visual Impairment in Patients Undergoing Neurosurgery for Compressive Macroadenoma : a Prospective Study. | NCT04074642 | Pituitary Adeno... | Neurosurgery | 18 Years - | Centre Hospitalier Universitaire de Nice | |
| Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System | NCT04743310 | Central Nervous... | tozuleristide Canvas imaging ... Surgical resect... | 18 Years - | Cedars-Sinai Medical Center | |
| Prospective Study of Children and Adolescents With Craniopharyngioma | NCT01272622 | Craniopharyngio... Obesity | Radiation wait and watch | 1 Day - 18 Years | Klinikum Oldenburg gGmbH | |
| Effects of Total Intravenous Anesthesia With Propofol-remifentanil Versus Inhalational Anesthesia With Sevoflurane on Quality of Recovery in Patients Undergoing Transsphenoidal Surgery for Pituitary Tumor | NCT02813044 | Pituitary Tumor | total intraveno... inhalation anes... | 19 Years - | Yonsei University | |
| A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases | NCT00124761 | Neoplasm Metast... Brain Neoplasm | Surgery + WBRT Radiosurgery + ... | 18 Years - | Royal Adelaide Hospital | |
| Effects of Total Intravenous Anesthesia With Propofol-remifentanil Versus Inhalational Anesthesia With Sevoflurane on Quality of Recovery in Patients Undergoing Transsphenoidal Surgery for Pituitary Tumor | NCT02813044 | Pituitary Tumor | total intraveno... inhalation anes... | 19 Years - | Yonsei University | |
| Vestibular Schwannoma - Radiosurgery or Expectation: V-REX. | NCT02249572 | Vestibular Schw... | gamma knife rad... | 18 Years - 70 Years | Haukeland University Hospital | |
| Re-craniotomy and Complications After Elective Neurosurgery | NCT03910556 | Brain Tumor Brain Metastase... Brain Cancer Brain Neoplasms | Propofol | 18 Years - 75 Years | Chiang Mai University | |
| Intraoperative Radiotherapy After the Resection of Brain Metastases | NCT03226483 | Brain Metastase... | Intraoperative ... | 18 Years - | Universitätsmedizin Mannheim | |
| Brain Awake Surgery Using Virtual Reality Headset | NCT03010943 | Brain Tumor Virtual Reality | Virtual reality... | 18 Years - | University Hospital, Angers | |
| Hemostasis Alterations in Neurosurgical Patients | NCT02652897 | Glioma Coagulopathy Acquired Platel... Thromboelastome... Surgery | Exposure to gli... Exposure to col... | 18 Years - | Hospitales Universitarios Virgen del Rocío | |
| Linking Digital Smartphone Behaviour With Brain Function | NCT03516162 | Brain Tumor Hydrocephalus Arteriovenous M... | There is no stu... | 18 Years - | University of Zurich | |
| The Management of Postoperative Craniotomy Pain in Pediatric Patients | NCT01576601 | Post Craniotomy... Cancer Epilepsy Vascular Malfor... Craniofacial Re... | - 18 Years | Johns Hopkins University | ||
| Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases | NCT01169129 | Metastases Cancer | surgery radiosurgery | 18 Years - 64 Years | Barretos Cancer Hospital | |
| The Management of Postoperative Craniotomy Pain in Pediatric Patients | NCT01576601 | Post Craniotomy... Cancer Epilepsy Vascular Malfor... Craniofacial Re... | - 18 Years | Johns Hopkins University | ||
| Activated Autologous T Cells Against Glioma Cancer Stem Cell Antigens for Patients With Recurrent Glioblastoma | NCT05341947 | Recurrent Gliob... | Activated T cel... | 18 Years - | Cedars-Sinai Medical Center | |
| Treatment of Brain AVMs (TOBAS) Study | NCT02098252 | Unruptured Brai... Ruptured Brain ... Arteriovenous M... AVM BAVM | Neurosurgery Radiation thera... Embolization | 5 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | |
| Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma | NCT00064779 | Malignant Gliom... Glioblastoma Mu... Anaplastic Astr... Anaplastic Olig... Mixed Oligoastr... | IL13-PE38QQR targeted fusion... surgery | 18 Years - | INSYS Therapeutics Inc | |
| Prospective Study of Children and Adolescents With Craniopharyngioma | NCT01272622 | Craniopharyngio... Obesity | Radiation wait and watch | 1 Day - 18 Years | Klinikum Oldenburg gGmbH | |
| Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas | NCT01502605 | Astrocytoma Glioma | 5-Aminolevulini... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Comparison of the Effects of Vecuronium and Cisatracurium on Electrophysiologic Monitoring During Neurosurgery | NCT01690364 | Motor Evoked Po... General Anesthe... Neurosurgery Brain Tumor Spine Tumor Cerebral Aneury... | MEP monitoring ... MEP monitoring ... | 20 Years - 75 Years | Samsung Medical Center | |
| Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation | NCT00659334 | Brain Neoplasms | Ferumoxtran-10 ... Neurosurgery | 5 Years - 75 Years | OHSU Knight Cancer Institute | |
| Comparison of Stroke Volume Variation-guided Normovolemic and Restrictive Fluid Management During Craniotomy: a Randomized Controlled Trial | NCT02113358 | Supratentorial ... Brain Tumor, Pr... Craniotomy | Intravenous col... | 20 Years - 70 Years | National Taiwan University Hospital | |
| Spectrum of Serum Sodium Disturbances in Patients With Non-sellar/Suprasellar Supratentorial Tumors | NCT03570203 | Supratentorial ... | Serum Sodium | 18 Years - | National Institute of Mental Health and Neuro Sciences, India | |
| Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia | NCT00993057 | Brain Neoplasms Intracranial An... | Insulin | 18 Years - | Northwestern University | |
| Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts | NCT04158284 | Craniopharyngio... Obesity | 1 Day - 18 Years | Klinikum Oldenburg gGmbH | ||
| Comparison of Stroke Volume Variation-guided Normovolemic and Restrictive Fluid Management During Craniotomy: a Randomized Controlled Trial | NCT02113358 | Supratentorial ... Brain Tumor, Pr... Craniotomy | Intravenous col... | 20 Years - 70 Years | National Taiwan University Hospital | |
| Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation | NCT00659334 | Brain Neoplasms | Ferumoxtran-10 ... Neurosurgery | 5 Years - 75 Years | OHSU Knight Cancer Institute | |
| Positron Emission Tomography (PET) With 3,4-dihydroxy-6-18F-fluoro-L-enylalanine (18F-FDOPA) Study | NCT01248754 | Cancer (High-gr... | Surgical neuron... | 18 Years - | British Columbia Cancer Agency | |
| Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life | NCT06381726 | Glioma Glioma, Maligna... | Resting State F... Up-front Motor ... Up-front Chemot... | 18 Years - | University of Milan | |
| Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma | NCT00064779 | Malignant Gliom... Glioblastoma Mu... Anaplastic Astr... Anaplastic Olig... Mixed Oligoastr... | IL13-PE38QQR targeted fusion... surgery | 18 Years - | INSYS Therapeutics Inc | |
| Spectrum of Serum Sodium Disturbances in Patients With Non-sellar/Suprasellar Supratentorial Tumors | NCT03570203 | Supratentorial ... | Serum Sodium | 18 Years - | National Institute of Mental Health and Neuro Sciences, India | |
| Determining Postoperative Recovery and the Impact of Adverse Events in Neurosurgery Based on Self-reported, App-based Longitudinal Assessment - a Collaborative Observational Research Project | NCT06352710 | Disc Disease Instabilities L... Brain Tumor Aneurysm | OP-Tracker App | 18 Years - | Cantonal Hospital of St. Gallen | |
| IORT After Surgical Resection of Brain Metastases | NCT05084092 | Brain Neoplasms | Intraoperative ... Brain surgery | 18 Years - | Institut Català d'Oncologia | |
| A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical Patients | NCT00952081 | Hypertension Brain Tumor Epilepsy | Clevidipine | 21 Years - | NYU Langone Health | |
| Intraoperative Radiotherapy After the Resection of Brain Metastases | NCT03226483 | Brain Metastase... | Intraoperative ... | 18 Years - | Universitätsmedizin Mannheim | |
| Dose Finding for Intraoperative Photodynamic Therapy of Glioblastoma | NCT04391062 | Glioblastoma | Gliolan Intraoperative ... | 18 Years - | University Hospital, Lille | |
| Arterial Pressure and Surgical Hemostasis in Elective Neurosurgery. | NCT05874050 | Neurosurgery Intracranial He... Supratentorial ... Blood Pressure | 18 Years - | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | ||
| Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System | NCT04743310 | Central Nervous... | tozuleristide Canvas imaging ... Surgical resect... | 18 Years - | Cedars-Sinai Medical Center | |
| Intra-operative Hyperspectral Imaging in Neurosurgery | NCT05294185 | Neurosurgery Neurovascular Neuro-Oncology | 18 Years - | King's College London | ||
| Dexmedetomidine on Intraoperative Somatosensory and Motor Evoked Potential Monitoring During Neurosurgery in Pediatric Patients | NCT01512147 | Tethered Spinal... Brain Tumor Cranio Cervical... | Isoflurane, Pro... | 2 Years - 12 Years | Oregon Health and Science University | |
| Improving Surgical Outcomes in Patients With Low Grade Gliomas Using Advanced Pre- and Intra-operative MRI | NCT02884947 | Brain Neoplasms | 18 Years - | University College, London | ||
| Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma | NCT04977375 | Glioblastoma Mu... | Pembrolizumab Stereotactic Ra... Surgical Resect... | 18 Years - | Cedars-Sinai Medical Center | |
| Intraoperative Hyperspectral Imaging for Fluorescence Guided Surgery in Low Grade Gliomas | NCT05397574 | Neurosurgery Neuro-Oncology Brain Tumor | 18 Years - | King's College London | ||
| Intra-operative Hyperspectral Imaging in Neurosurgery | NCT05294185 | Neurosurgery Neurovascular Neuro-Oncology | 18 Years - | King's College London | ||
| Pre- Versus Post-operative SRS for Resectable Brain Metastases | NCT04474925 | Brain Metastase... | Brain Surgery Stereotactic Ra... | 18 Years - 100 Years | AHS Cancer Control Alberta | |
| Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia | NCT00993057 | Brain Neoplasms Intracranial An... | Insulin | 18 Years - | Northwestern University | |
| Linking Digital Smartphone Behaviour With Brain Function | NCT03516162 | Brain Tumor Hydrocephalus Arteriovenous M... | There is no stu... | 18 Years - | University of Zurich | |
| Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases | NCT01169129 | Metastases Cancer | surgery radiosurgery | 18 Years - 64 Years | Barretos Cancer Hospital | |
| Arterial Pressure and Surgical Hemostasis in Elective Neurosurgery. | NCT05874050 | Neurosurgery Intracranial He... Supratentorial ... Blood Pressure | 18 Years - | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | ||
| Brain Awake Surgery Using Virtual Reality Headset | NCT03010943 | Brain Tumor Virtual Reality | Virtual reality... | 18 Years - | University Hospital, Angers | |
| Bevacizumab With or Without Surgery for Adult Glioblastomas | NCT01413438 | Glioblastoma Brain Neoplasm | Craniotomy | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts | NCT04158284 | Craniopharyngio... Obesity | 1 Day - 18 Years | Klinikum Oldenburg gGmbH | ||
| Hemostasis Alterations in Neurosurgical Patients | NCT02652897 | Glioma Coagulopathy Acquired Platel... Thromboelastome... Surgery | Exposure to gli... Exposure to col... | 18 Years - | Hospitales Universitarios Virgen del Rocío | |
| Pre- Versus Post-operative SRS for Resectable Brain Metastases | NCT04474925 | Brain Metastase... | Brain Surgery Stereotactic Ra... | 18 Years - 100 Years | AHS Cancer Control Alberta | |
| The Management of Postoperative Craniotomy Pain in Pediatric Patients | NCT01576601 | Post Craniotomy... Cancer Epilepsy Vascular Malfor... Craniofacial Re... | - 18 Years | Johns Hopkins University | ||
| Positron Emission Tomography (PET) With 3,4-dihydroxy-6-18F-fluoro-L-enylalanine (18F-FDOPA) Study | NCT01248754 | Cancer (High-gr... | Surgical neuron... | 18 Years - | British Columbia Cancer Agency | |
| Implementation of 23 Hour Surgery Model in a Tertiary Hospital | NCT04142203 | Ambulatory Surg... Laparoscopy Shoulder Imping... Ovarian Cysts Cholecystolithi... Appendicitis Gynecologic Sur... Ambulatory Surg... Neurosurgery | 23 h surgery | 18 Years - 100 Years | Kuopio University Hospital | |
| IORT After Surgical Resection of Brain Metastases | NCT05084092 | Brain Neoplasms | Intraoperative ... Brain surgery | 18 Years - | Institut Català d'Oncologia | |
| Implementation of 23 Hour Surgery Model in a Tertiary Hospital | NCT04142203 | Ambulatory Surg... Laparoscopy Shoulder Imping... Ovarian Cysts Cholecystolithi... Appendicitis Gynecologic Sur... Ambulatory Surg... Neurosurgery | 23 h surgery | 18 Years - 100 Years | Kuopio University Hospital |
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